3-(Trifluoromethyl)pyrid-2-ylhydrazine

The 3-(Trifluoromethyl)pyrid-2-ylhydrazine, with CAS registry number 89570-83-2, belongs to the following product category: Pyridines. It has the systematic name of 2-hydrazino-3-(trifluoromethyl)pyridine. Its molecular weight is 177.13. And the chemical formula of this chemical is C₆H₆F₃N₃.

Physical properties of 3-(Trifluoromethyl)pyrid-2-ylhydrazine: (1)ACD/LogP: 0.95; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.92; (4)ACD/LogD (pH 7.4): 0.95; (5)ACD/BCF (pH 5.5): 2.92; (6)ACD/BCF (pH 7.4): 3.1; (7)ACD/KOC (pH 5.5): 73.64; (8)ACD/KOC (pH 7.4): 78.2; (9)#H bond acceptors: 3; (10)#H bond donors: 3; (11)#Freely Rotating Bonds: 1; (12)Polar Surface Area: 19.37 Å²; (13)Index of Refraction: 1.528; (14)Molar Refractivity: 37.83 cm³; (15)Molar Volume: 122.7 cm³; (16)Polarizability: 14.99×10^-24cm³; (17)Surface Tension: 38.9 dyne/cm; (18)Density: 1.442 g/cm³; (19)Flash Point: 105 °C; (20)Enthalpy of Vaporization: 48.73 kJ/mol; (21)Boiling Point: 250.1 °C at 760 mmHg; (22)Vapour Pressure: 0.0221 mmHg at 25°C.

Preparation: this chemical can be prepared by 2-chloro-3-trifluoromethylpyridine. This reaction will need reagent NH₂NH₂^.H₂O and solvent ethanol. The reaction time is 3 hour(s).

Uses of 3-(Trifluoromethyl)pyrid-2-ylhydrazine: it can be used to produce 8-trifluoromethyl-tetrazolo[1,5-a]pyridine. This reaction will need reagent NaNO₂, aq. HCl. The yield is about 85%.

When you are using this chemical, please be cautious about it as the following:
The 3-(Trifluoromethyl)pyrid-2-ylhydrazine irritates to eyes, respiratory system and skin. When use it, wear suitable protective clothing, gloves and eye/face protection. If contact with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1)SMILES: FC(F)(F)c1cccnc1NN
(2)InChI: InChI=1/C6H6F3N3/c7-6(8,9)4-2-1-3-11-5(4)12-10/h1-3H,10H2,(H,11,12)
(3)InChIKey: TWPMJXZSKBAITM-UHFFFAOYAY
(4)Std. InChI: InChI=1S/C6H6F3N3/c7-6(8,9)4-2-1-3-11-5(4)12-10/h1-3H,10H2,(H,11,12)
(5)Std. InChIKey: TWPMJXZSKBAITM-UHFFFAOYSA-N