3,3-Dichloro-1,1,1,2,2-pentafluoropropane supplier

Name
3,3-Dichloro-1,1,1,2,2-pentafluoropropane
EINECS 207-016-9
CAS No. 422-56-0
Article Data9
CAS DataBase
Density 1.55
Solubility
Melting Point -94 ºC
Formula C3H Cl2 F5
Boiling Point 53.3 °C at 760 mmHg
Molecular Weight 202.939
Flash Point °C
Transport Information
Appearance
Safety Low toxicity ingestion, inhalation, and skin contact. When heated to decomposition it emits toxic vapors of F⁻ and Cl⁻.
Risk Codes 20/21/22-59
Molecular Structure
Hazard Symbols Low toxicity ingestion, inhalation, and skin contact.
Synonyms 1,1,1,2,2-Pentafluoro-3,3-dichloropropane;1,1-Dichloro-2,2,3,3,3-pentafluoropropane; 3,3-Dichloro-1,1,1,2,2-pentafluoropropane;Fron 225; HCFC 225ca; R 225b; R 225ca
PSA 0.00000
LogP 2.98770

Synthetic route

: 422-54-8
1,1,3-trichloro-2,2,3,3-tetrafluoropropane

A: 422-57-1
3-chloro-1,1,1,2,2,3-hexafluoropropane

B: 422-55-9
1-chloro-1,1,2,2,3,3-hexafluoropropane

C: 422-56-0
3,3-dichloro-1,1,1,2,2-pentafluoropropane

D: 507-55-1
1,3-dichloro-1,1,2,2,3-pentafluoropropane

Conditions

Conditions	Yield
With hydrogen fluoride; chromium(III) oxide at 280℃;	A 3% B 16% C 5% D 44%

...Expand

: 75-45-6
Chlorodifluoromethane

: 79-38-9
Chlorotrifluoroethylene

A: 422-56-0
3,3-dichloro-1,1,1,2,2-pentafluoropropane

B: 507-55-1
1,3-dichloro-1,1,2,2,3-pentafluoropropane

C: 422-54-8
1,1,3-trichloro-2,2,3,3-tetrafluoropropane

D: 422-47-9
1,1,2-trichloro-2,3,3,3-tetrafluoropropane

Conditions

Conditions	Yield
With aluminium trichloride at 0 - 10℃; for 10h; Further byproducts given;	A 0.6% B 12.4% C 30.5% D 12.5%

...Expand

: 422-02-6
3-chloro-1,1,1,2,2-pentafluoropropane

: 422-56-0
3,3-dichloro-1,1,1,2,2-pentafluoropropane

Conditions

Conditions	Yield
With water; chlorine Irradiation.mit UV-Licht;

: 422-02-6
3-chloro-1,1,1,2,2-pentafluoropropane

A: 422-56-0
3,3-dichloro-1,1,1,2,2-pentafluoropropane

B: 4259-43-2
1,1,1-trichloro-2,2,3,3,3-pentafluoropropane

Conditions

Conditions	Yield
With chlorine at 250℃;

: 422-58-2
3-chloro-1,1,1,2,2-pentafluoro-3-iodo-propane

: 422-56-0
3,3-dichloro-1,1,1,2,2-pentafluoropropane

Conditions

Conditions	Yield
With chlorine Irradiation;

: 422-58-2
3-chloro-1,1,1,2,2-pentafluoro-3-iodo-propane

: 7782-50-5
chlorine

: 422-56-0
3,3-dichloro-1,1,1,2,2-pentafluoropropane

Conditions

Conditions	Yield
im UV-Licht;

: 4259-43-2
1,1,1-trichloro-2,2,3,3,3-pentafluoropropane

A: 422-02-6
3-chloro-1,1,1,2,2-pentafluoropropane

B: 1599-41-3
2,2,3-trichloro-1,1,1,3,3-pentafluoropropane

C: 754-12-1
2,3,3,3-tetrafluoro-propene

D: 422-56-0
3,3-dichloro-1,1,1,2,2-pentafluoropropane

E: 422-86-6
perfluoropropyl chloride

F: 421-48-7
1,1,1,2-tetrafluoropropane

G: 677-55-4
1-chloro-1,1,2,2,3-pentafluoropropane

H: C2F5CH=CClC2F5

I: 162763-52-2
3,4-dichlorodecafluorohex-3-ene

J: 1814-88-6
1,1,1,2,2-pentafluoropropane

Conditions

Conditions	Yield
With hydrogen fluoride; hydrogen; fluorided Pd on Al2O3 at 350℃; Product distribution / selectivity;

...Expand

: 4259-43-2
1,1,1-trichloro-2,2,3,3,3-pentafluoropropane

A: 422-02-6
3-chloro-1,1,1,2,2-pentafluoropropane

B: 1599-41-3
2,2,3-trichloro-1,1,1,3,3-pentafluoropropane

C: 421-07-8
1,1,1-trifluoropropane

D: 422-56-0
3,3-dichloro-1,1,1,2,2-pentafluoropropane

E: 422-86-6
perfluoropropyl chloride

F: 421-48-7
1,1,1,2-tetrafluoropropane

G: 677-55-4
1-chloro-1,1,2,2,3-pentafluoropropane

H: 1814-88-6
1,1,1,2,2-pentafluoropropane

Conditions

Conditions	Yield
With hydrogen; fluorided platinum on aluminum oxide at 250℃; Product distribution / selectivity;

...Expand

: 4259-43-2
1,1,1-trichloro-2,2,3,3,3-pentafluoropropane

A: 422-02-6
3-chloro-1,1,1,2,2-pentafluoropropane

B: 1599-41-3
2,2,3-trichloro-1,1,1,3,3-pentafluoropropane

C: 754-12-1
2,3,3,3-tetrafluoro-propene

D: 422-56-0
3,3-dichloro-1,1,1,2,2-pentafluoropropane

E: 422-86-6
perfluoropropyl chloride

F: 677-55-4
1-chloro-1,1,2,2,3-pentafluoropropane

G: C2F5CH=CClC2F5

H: 162763-52-2
3,4-dichlorodecafluorohex-3-ene

I: 1814-88-6
1,1,1,2,2-pentafluoropropane

Conditions

Conditions	Yield
With hydrogen fluoride; hydrogen; fluorided Pd on Al2O3 at 350℃; Product distribution / selectivity;

...Expand

: 507-55-1
1,3-dichloro-1,1,2,2,3-pentafluoropropane

A: 422-56-0
3,3-dichloro-1,1,1,2,2-pentafluoropropane

B: 128903-21-9
2,2-dichloro-1,1,1,3,3-pentafluoropropane

Conditions

Conditions	Yield
aluminum (III) chloride; trichlorofluoromethane at 0 - 50℃; Product distribution / selectivity;

: 507-55-1
1,3-dichloro-1,1,2,2,3-pentafluoropropane

A: 422-55-9
1-chloro-1,1,2,2,3,3-hexafluoropropane

B: 422-56-0
3,3-dichloro-1,1,1,2,2-pentafluoropropane

C: 422-47-9
1,1,2-trichloro-2,3,3,3-tetrafluoropropane

D: 128903-21-9
2,2-dichloro-1,1,1,3,3-pentafluoropropane

Conditions

Conditions	Yield
partially fluorinated aluminum oxide at 300℃; for 10.0056h; Product distribution / selectivity; Inert atmosphere;

...Expand

: 507-55-1
1,3-dichloro-1,1,2,2,3-pentafluoropropane

: 128903-21-9
2,2-dichloro-1,1,1,3,3-pentafluoropropane

A: 422-55-9
1-chloro-1,1,2,2,3,3-hexafluoropropane

B: 422-56-0
3,3-dichloro-1,1,1,2,2-pentafluoropropane

C: 422-47-9
1,1,2-trichloro-2,3,3,3-tetrafluoropropane

Conditions

Conditions	Yield
partially fluorinated aluminum oxide at 300℃; for 10.0056h; Inert atmosphere;

...Expand

: 507-55-1
1,3-dichloro-1,1,2,2,3-pentafluoropropane

: 128903-21-9
2,2-dichloro-1,1,1,3,3-pentafluoropropane

: 422-56-0
3,3-dichloro-1,1,1,2,2-pentafluoropropane

Conditions

Conditions	Yield
partially fluorinated aluminum oxide at 230℃; for 10.0056h; Product distribution / selectivity; Inert atmosphere;

: 507-55-1
1,3-dichloro-1,1,2,2,3-pentafluoropropane

: 422-56-0
3,3-dichloro-1,1,1,2,2-pentafluoropropane

Conditions

Conditions	Yield
With aluminum oxide at 250 - 400℃; for 4h; Reagent/catalyst; Inert atmosphere;

: 422-56-0
3,3-dichloro-1,1,1,2,2-pentafluoropropane

: 422-59-3
2,2,3,3,3-pentafluoropropionyl chloride

Conditions

Conditions	Yield
In chlorine	99%

: 5754-34-7
4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

: 422-56-0
3,3-dichloro-1,1,1,2,2-pentafluoropropane

: 507-55-1
1,3-dichloro-1,1,2,2,3-pentafluoropropane

: 2641-34-1
perfluoro-2,5-dimethyl-3,6-dioxanonanoyl fluoride

: C16H13O6F17

Conditions

Conditions	Yield
With sodium fluoride at 20℃; for 20h;	67%

...Expand

: 422-56-0
3,3-dichloro-1,1,1,2,2-pentafluoropropane

: 754-12-1
2,3,3,3-tetrafluoro-propene

Conditions

Conditions	Yield
With methane; oxygen; nickel at 675℃; under 1277.21 Torr; Product distribution / selectivity;	19%
With methylene chloride; oxygen; nickel at 675℃; under 1277.21 Torr; Product distribution / selectivity;	19%

: 422-56-0
3,3-dichloro-1,1,1,2,2-pentafluoropropane

: 507-55-1
1,3-dichloro-1,1,2,2,3-pentafluoropropane

A: 421-48-7
1,1,1,2-tetrafluoropropane

B: 1814-88-6
1,1,1,2,2-pentafluoropropane

Conditions

Conditions	Yield
With hydrogen; potassium acetate; palladium 10% on activated carbon In ethanol at 65℃; under 7757.43 Torr; for 16h; Product distribution / selectivity;

...Expand

: 422-56-0
3,3-dichloro-1,1,1,2,2-pentafluoropropane

: 507-55-1
1,3-dichloro-1,1,2,2,3-pentafluoropropane

A: 754-12-1
2,3,3,3-tetrafluoro-propene

B: 421-48-7
1,1,1,2-tetrafluoropropane

C: 1814-88-6
1,1,1,2,2-pentafluoropropane

Conditions

Conditions	Yield
With hydrogen; potassium acetate; palladium 10% on activated carbon In ethanol at 120℃; under 7757.43 Torr; for 16h; Product distribution / selectivity;

...Expand

: 422-56-0
3,3-dichloro-1,1,1,2,2-pentafluoropropane

: 507-55-1
1,3-dichloro-1,1,2,2,3-pentafluoropropane

A: 422-02-6
3-chloro-1,1,1,2,2-pentafluoropropane

B: 754-12-1
2,3,3,3-tetrafluoro-propene

Conditions

Conditions	Yield
With hydrogen; potassium acetate; palladium 10% on activated carbon In ethanol at 40 - 45℃; under 7757.43 Torr; for 16h; Product distribution / selectivity;

...Expand

: 422-56-0
3,3-dichloro-1,1,1,2,2-pentafluoropropane

: 507-55-1
1,3-dichloro-1,1,2,2,3-pentafluoropropane

A: 422-02-6
3-chloro-1,1,1,2,2-pentafluoropropane

B: 1814-88-6
1,1,1,2,2-pentafluoropropane

Conditions

Conditions	Yield
With ammonium formate; tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran at 98 - 100℃; under 10343.2 Torr; for 22h; Product distribution / selectivity;
With hydrogen; 1% Pd/C at 80 - 145℃; under 760.051 - 1520.1 Torr; Product distribution / selectivity; Gas phase;

...Expand

: 422-56-0
3,3-dichloro-1,1,1,2,2-pentafluoropropane

A: 422-02-6
3-chloro-1,1,1,2,2-pentafluoropropane

B: 754-12-1
2,3,3,3-tetrafluoro-propene

C: 1814-88-6
1,1,1,2,2-pentafluoropropane

Conditions

Conditions	Yield
With hydrogen; acid treated activated carbon at 350 - 500℃; Product distribution / selectivity; Gas phase;

...Expand

: 422-56-0
3,3-dichloro-1,1,1,2,2-pentafluoropropane

: 507-55-1
1,3-dichloro-1,1,2,2,3-pentafluoropropane

: 13474-88-9
1,1-dichloro-1,2,2,3,3-pentafluoropropane

Conditions

Conditions	Yield
With SbCl5; SbF3 In chloroform

: 422-56-0
3,3-dichloro-1,1,1,2,2-pentafluoropropane

: 507-55-1
1,3-dichloro-1,1,2,2,3-pentafluoropropane

A: 422-02-6
3-chloro-1,1,1,2,2-pentafluoropropane

B: 421-07-8
1,1,1-trifluoropropane

C: 754-12-1
2,3,3,3-tetrafluoro-propene

D: 421-48-7
1,1,1,2-tetrafluoropropane

E: 677-55-4
1-chloro-1,1,2,2,3-pentafluoropropane

F: 1814-88-6
1,1,1,2,2-pentafluoropropane

G: 679-86-7
1,1,2,2,3-pentafluoropropane

H: 679-99-2
1-chloro-1,2,2,3,3-pentafluoropropane

Conditions

Conditions	Yield
With hydrogen; fluorided Pd/Al2O3 at 300 - 350℃; Product distribution / selectivity;

...Expand

: 422-02-6
3-chloro-1,1,1,2,2-pentafluoropropane

: 422-56-0
3,3-dichloro-1,1,1,2,2-pentafluoropropane

A: 2804-55-9
1,1-dichloro-2,3,3,3-tetrafluoro-1-propene

B: 111512-50-6
cis-1,3-dichloro-1,2,3,3-tetrafluoro-1-propene

C: 111512-61-9
trans-1,3-dichloro-1,2,3,3-tetrafluoro-1-propene

Conditions

Conditions	Yield
25weight percent chromium (III) chloride on carbon treated with HF at 300-425C at 350℃; under 760.051 Torr; for 0.00833333h;

...Expand

: 422-56-0
3,3-dichloro-1,1,1,2,2-pentafluoropropane

: 2804-55-9
1,1-dichloro-2,3,3,3-tetrafluoro-1-propene

Conditions

Conditions	Yield
25weight percent chromium (III) chloride on carbon treated with HF at 300-425C at 350℃; under 760.051 Torr; for 0.00833333h;
With potassium hydroxide; tetrabutylammomium bromide In water at 0 - 45℃;
With potassium hydroxide; tetrabutylammomium bromide In water at 0 - 45℃; for 1h;

: 422-56-0
3,3-dichloro-1,1,1,2,2-pentafluoropropane

: 151771-09-4
1-chloro-2,3,3,3-tetrafluoropropane

A: 754-12-1
2,3,3,3-tetrafluoro-propene

B: 2804-55-9
1,1-dichloro-2,3,3,3-tetrafluoro-1-propene

Conditions

Conditions	Yield
With potassium hydroxide; tetrabutylammomium bromide In water at 0 - 10℃; for 20h; Product distribution / selectivity;

...Expand

3,3-Dichloro-1,1,1,2,2-pentafluoropropane Chemical Properties

Molecular Formula: C₃HCl₂F₅
Molecular Weight: 202.94
EINECS: 207-016-9
Melting Point: -94°C
Density: 1.578 g/cm³
Index of Refraction: 1.331
CAS Registry Number: 422-56-0
Enthalpy of Vaporization: 28.42 kJ/mol
Boiling Point: 53.3 °C at 760 mmHg
Vapour Pressure: 270 mmHg at 25°C
Appearance: Colorless odorless liquid.
Air & Water Reactions: Slightly soluble in water.
IUPAC Name: 3,3-dichloro-1,1,1,2,2-pentafluoropropane
Synonyms: HCFC-225CA ; Dichloropentafluoropropane ; 1,1,1,2,2-pentafluoro-3,3-dichloropropane ; 1,1-Dichlor-2,2,3,3,3-pentafluorpropane ; 1,1-Dichloro-2,2,3,3,3-pentafluoropropane(HCFC-225ca) ; 3,3-dichloro-1,1,1,2,2-pentafluoropropane
Following is the molecular structure of 3,3-Dichloro-1,1,1,2,2-pentafluoropropane (CAS NO. 422-56-0):

3,3-Dichloro-1,1,1,2,2-pentafluoropropane Production

Reactivity Profile: 3,3-Dichloro-1,1,1,2,2-pentafluoropropane (CAS NO. 422-56-0) is chemically inert in many situations, but can react violently with strong reducing agents such as the very active metals and the active metals. They suffer oxidation with strong oxidizing agents and under extremes of temperature. Strong bases may release toxic gases.

3,3-Dichloro-1,1,1,2,2-pentafluoropropane Toxicity Data With Reference

1.	orl-rat LD50:>5 g/kg	IJTOFN International Journal of Toxicology. 19 (2000),367.
2.	ihl-rat LC50:37,300 ppm/4H	JJATDK JAT, Journal of Applied Toxicology. 19 (1999),101.
3.	skn-rat LD50:>2 g/kg	IJTOFN International Journal of Toxicology. 19 (2000),367.

3,3-Dichloro-1,1,1,2,2-pentafluoropropane Safety Profile

Low toxicity ingestion, inhalation, and skin contact. When heated to decomposition it emits toxic vapors of F⁻ and Cl⁻.
Safety Information of 3,3-Dichloro-1,1,1,2,2-pentafluoropropane (CAS NO. 422-56-0):
Hazard Codes: Xi Irritant
Risk Statements: 20/21/22-59
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
R59: Dangerous to the ozone layer.
Safety Statements: 23-36/37/39
S23: Do not breathe vapour.
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
RIDADR: 3082
Hazard Note: Irritant

Product Name

3,3-Dichloro-1,1,1,2,2-pentafluoropropane

Synthetic route

3,3-Dichloro-1,1,1,2,2-pentafluoropropane Chemical Properties

3,3-Dichloro-1,1,1,2,2-pentafluoropropane Production

3,3-Dichloro-1,1,1,2,2-pentafluoropropane Toxicity Data With Reference

3,3-Dichloro-1,1,1,2,2-pentafluoropropane Safety Profile

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