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Shanghai Finebiotech Co.,Ltd.

Shanghai Finebiotech Co.,Ltd.was established in 2020, which providing professional chemical services. As a customer-oriented company, we have distinguished ourself from others in providing worldwide customers with cost-effective and efficient service

4-(2-Hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

Cas:5754-34-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

1,3-Dioxolane-4-ethanol,2,2-dimethyl- Manufacturer/High quality/Best price/In stock

Cas:5754-34-7

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

4-(2-HYDROXYETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE Basic information Product Name: 4-(2-HYDROXYETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE Synonyms: 4-(2-HYDROXYETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE;(RAC)-

4-(2-HYDROXYETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE

Cas:5754-34-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 5754-34-7 with competitive price

Cas:5754-34-7

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

4-(2-Hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

Cas:5754-34-7

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W

4-(2-HYDROXYETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE CAS5754-34-7

Cas:5754-34-7

Min.Order:1 Kilogram

FOB Price: $7.0 / 9.0

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: 4-(2-HYDROXYETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE CAS: 5754-34-7 MF: C7H14O3 MW: 146.18 EINECS: Product Categories: Mol File: 5754-34-7.mol 4-(2-HYDROXYETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE Structure 4-(2-HYDROXYETHYL)-

4-(2-Hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

Cas:5754-34-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

1,3-Dioxolane-4-ethanol,2,2-dimethyl-

Cas:5754-34-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1,3-Dioxolane-4-ethanol,2,2-dimethyl-

Cas:5754-34-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

1,3-Dioxolane-4-ethanol,2,2-dimethyl-

Cas:5754-34-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

1,3-Dioxolane-4-ethanol,2,2-dimethyl-

Cas:5754-34-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

4-(2-Hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

Cas:5754-34-7

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

4-(2-Hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

Cas:5754-34-7

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

4-(2-HYDROXYETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE

Cas:5754-34-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

4-(2-HYDROXYETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE

Cas:5754-34-7

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

4-(2-Hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

Cas:5754-34-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

4-(2-Hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

Cas:5754-34-7

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

4-(2-Hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

Cas:5754-34-7

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

(Rac)-2-(2,2-dimethyl[1,3]dioxolane-4yl)ethanol

Cas:5754-34-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

4-(2-Hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

Cas:5754-34-7

Min.Order:0

Negotiable

Type:Other

inquiry

Kunshan Push Trading Co.,LTD

ADVANTAGE 1.Professional: More than 10 years chemical exporting experience. We have produced chemical more than fifteen years, 95% products are for export . More than 10 years chemical exporting experience. Good and stabilized factory price. 2.

4-(2-HYDROXYETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE

Cas:5754-34-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

4-(2-Hydroxyethyl)-2,2-Dimethyl-1,3-Dioxolane

Cas:5754-34-7

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

1,3-Dioxolane-4-ethanol,2,2-dimethyl-

Cas:5754-34-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

We are a trading company aiming at providing high-quality services to customers. Established for many years, with good reputation in the industry Storage:Sealed and preserved Application:Fine chemical intermediates, used as the main raw material for

4-(2-Hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

Cas:5754-34-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Application:Chemical intermediate

2-(2,2-Dimethyl-1,3-dioxolan-4-yl)ethanol

Cas:5754-34-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hubei Langyou International Trading Co., Ltd

4-(2-Hydroxyethyl)-2,2-dimethyl-1,3-dioxolane Application:4-(2-Hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

4-(2-Hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

Cas:5754-34-7

Min.Order:0

Negotiable

Type:Other

inquiry

Changchun Artel lmport and Export trade company

Supply top quality products with a reasonable price Application:api

5754-34-7

Cas:5754-34-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

1,3-Dioxolane-4-ethanol,2,2-dimethyl- cas 5754-34-7Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

1,3-Dioxolane-4-ethanol,2,2-dimethyl- cas 5754-34-7

Cas:5754-34-7

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

4-(2-HYDROXYETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE

Cas:5754-34-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Best quality with low price Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Shanghai

4-(2-Hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

Cas:5754-34-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

D,L-1,2,4-butanetriol
3068-00-6

D,L-1,2,4-butanetriol

acetone
67-64-1

acetone

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
5754-34-7

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

Conditions
ConditionsYield
With toluene-4-sulfonic acid at 20℃; for 4h;98%
With toluene-4-sulfonic acid at 20℃; for 20h;97%
With toluene-4-sulfonic acid86%
4-[2-(4-methoxy-benzyloxy)ethyl]-2,2-dimethyl-[1,3]dioxolane
167629-45-0

4-[2-(4-methoxy-benzyloxy)ethyl]-2,2-dimethyl-[1,3]dioxolane

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
5754-34-7

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

Conditions
ConditionsYield
With 2,3-dicyano-5,6-dichloro-p-benzoquinone In dichloromethane; water90%
D,L-1,2,4-butanetriol
3068-00-6

D,L-1,2,4-butanetriol

2,2-dimethoxy-propane
77-76-9

2,2-dimethoxy-propane

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
5754-34-7

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

Conditions
ConditionsYield
With camphor-10-sulfonic acid85%
With camphor-10-sulfonic acid In acetonitrile at 20℃;80%
Stage #1: D,L-1,2,4-butanetriol; 2,2-dimethoxy-propane With pyridinium p-toluenesulfonate In acetone at 20℃; for 4h; Reflux;
Stage #2: In methanol at 0℃; for 12h;
74%
methylene chloride (CH2 Cl2)

methylene chloride (CH2 Cl2)

para-toluene sulfonic acid (p-TsOH)

para-toluene sulfonic acid (p-TsOH)

D,L-1,2,4-butanetriol
3068-00-6

D,L-1,2,4-butanetriol

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
5754-34-7

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

Conditions
ConditionsYield
With magnesium sulfate In methanol; water; acetone75%
tert-butyl-[2-(2,2-dimethyl-[1,3]dioxolan-4-yl)-ethoxy]-dimethyl-silane

tert-butyl-[2-(2,2-dimethyl-[1,3]dioxolan-4-yl)-ethoxy]-dimethyl-silane

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
5754-34-7

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

Conditions
ConditionsYield
With acetonyltriphenylphosphonium bromide In methanol; dichloromethane at 20℃; for 0.25h;72%
D,L-1,2,4-butanetriol
3068-00-6

D,L-1,2,4-butanetriol

2-Methoxypropene
116-11-0

2-Methoxypropene

A

(2,2-dimethyl-[1,3]dioxan-4-yl)-methanol
56476-33-6

(2,2-dimethyl-[1,3]dioxan-4-yl)-methanol

B

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
5754-34-7

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

C

2-(2,2-dimethyl-1,3-dioxolan-4-ylethoxy)-2-methoxypropane

2-(2,2-dimethyl-1,3-dioxolan-4-ylethoxy)-2-methoxypropane

D

2-(2,2-dimethyl-1,3-dioxan-4-ylmethoxy)-2-methoxypropane

2-(2,2-dimethyl-1,3-dioxan-4-ylmethoxy)-2-methoxypropane

E

2,2-bis(2,2-dimethyl-1,3-dioxolan-4-ylethoxy)propane

2,2-bis(2,2-dimethyl-1,3-dioxolan-4-ylethoxy)propane

Conditions
ConditionsYield
With butyltin(IV) chloride dihydroxide for 90h; Product distribution; Ambient temperature; var. of reagent, ratio, time, further with 2,2-dimethoxypropane;A 3.0 g
B 13.3 g
C n/a
D n/a
E 0.4 g
2-(2,2-dimethyl-1,3-dioxolan-4-yl)acetaldehyde
83141-42-8

2-(2,2-dimethyl-1,3-dioxolan-4-yl)acetaldehyde

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
5754-34-7

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

Conditions
ConditionsYield
reduction;
D,L-1,2,4-butanetriol
3068-00-6

D,L-1,2,4-butanetriol

2,2-dimethoxy-propane
77-76-9

2,2-dimethoxy-propane

acetone
67-64-1

acetone

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
5754-34-7

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

Conditions
ConditionsYield
With toluene-4-sulfonic acid
D,L-1,2,4-butanetriol
3068-00-6

D,L-1,2,4-butanetriol

acetone
67-64-1

acetone

A

(2,2-dimethyl-[1,3]dioxan-4-yl)-methanol
56476-33-6

(2,2-dimethyl-[1,3]dioxan-4-yl)-methanol

B

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
5754-34-7

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

Conditions
ConditionsYield
toluene-4-sulfonic acid Yield given. Yields of byproduct given. Title compound not separated from byproducts;
With toluene-4-sulfonic acid Yield given. Yields of byproduct given. Title compound not separated from byproducts;
D,L-1,2,4-butanetriol
3068-00-6

D,L-1,2,4-butanetriol

2,2-dimethoxy-propane
77-76-9

2,2-dimethoxy-propane

A

(2,2-dimethyl-[1,3]dioxan-4-yl)-methanol
56476-33-6

(2,2-dimethyl-[1,3]dioxan-4-yl)-methanol

B

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
5754-34-7

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

Conditions
ConditionsYield
With pyridinium p-toluenesulfonate In acetone at 20℃; for 0.5h;
4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
5754-34-7

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

2-(2,2-dimethyl-1,3-dioxolan-4-yl)ethyl methanesulfonate
76099-47-3

2-(2,2-dimethyl-1,3-dioxolan-4-yl)ethyl methanesulfonate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 1h;100%
With triethylamine In toluene at 20℃; for 4h; mesylation;94%
With triethylamine In dichloromethane at 0℃; for 1.5h;91%
4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
5754-34-7

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

p-toluenesulfonyl chloride
98-59-9

p-toluenesulfonyl chloride

2-(2,2-dimethyl-1,3-dioxolan-4-yl)ethyl 4-methylbenzenesulfonate
55559-75-6

2-(2,2-dimethyl-1,3-dioxolan-4-yl)ethyl 4-methylbenzenesulfonate

Conditions
ConditionsYield
With dmap; triethylamine In dichloromethane 1) 0-5 deg C, 3.5 h; 2) rt, 6 h;99%
With pyridine 1.) 0 deg C, 2 h, 2.) -20 deg C, overnight;87%
With pyridine at 0 - 20℃; for 24h;81%
4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
5754-34-7

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

allyl bromide
106-95-6

allyl bromide

(±)-4-(2-(allyloxy)ethyl)-2,2-dimethyl-1,3-dioxolane

(±)-4-(2-(allyloxy)ethyl)-2,2-dimethyl-1,3-dioxolane

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 20℃; for 6h;98%
4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
5754-34-7

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

2-(2,2-dimethyl-1,3-dioxolan-4-yl)acetaldehyde
83141-42-8

2-(2,2-dimethyl-1,3-dioxolan-4-yl)acetaldehyde

Conditions
ConditionsYield
With pyridinium chlorochromate In dichloromethane Ambient temperature;93%
With aluminum oxide; pyridinium chlorochromate In dichloromethane at 0 - 20℃;75%
With camphor-10-sulfonic acid; pyridinium chlorochromate In dichloromethane for 3h;74%
4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
5754-34-7

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

benzyl bromide
100-39-0

benzyl bromide

(+/-)-4-(2-benzyloxyethyl)-2,2-dimethyl-1,3-dioxolane
94426-71-8

(+/-)-4-(2-benzyloxyethyl)-2,2-dimethyl-1,3-dioxolane

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; Inert atmosphere;91%
With tetra-(n-butyl)ammonium iodide; sodium hydride In N,N-dimethyl-formamide for 3h; Ambient temperature;71%
With sodium hydride 1.) DMF, RT, 0.5 h, 2.) 30 deg C, 1.5 h; Yield given. Multistep reaction;
4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
5754-34-7

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

O-(4-methoxybenzyl)-trichloroacetimidate
89238-99-3

O-(4-methoxybenzyl)-trichloroacetimidate

4-[2-(4-methoxy-benzyloxy)ethyl]-2,2-dimethyl-[1,3]dioxolane
167629-45-0

4-[2-(4-methoxy-benzyloxy)ethyl]-2,2-dimethyl-[1,3]dioxolane

Conditions
ConditionsYield
With camphor-10-sulfonic acid In dichloromethane91%
With camphor-10-sulfonic acid In dichloromethane at 20℃; for 12h;91%
4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
5754-34-7

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

3-chloroprop-1-ene
107-05-1

3-chloroprop-1-ene

(±)-4-(2-(allyloxy)ethyl)-2,2-dimethyl-1,3-dioxolane

(±)-4-(2-(allyloxy)ethyl)-2,2-dimethyl-1,3-dioxolane

Conditions
ConditionsYield
With sodium hydroxide In toluene at 30℃; for 6h;90%
With sodium hydroxide at 30℃; for 2h;
4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
5754-34-7

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

oleoyl chloride

oleoyl chloride

(Z)-Octadec-10-enoic acid 2-(2,2-dimethyl-[1,3]dioxolan-4-yl)-ethyl ester

(Z)-Octadec-10-enoic acid 2-(2,2-dimethyl-[1,3]dioxolan-4-yl)-ethyl ester

Conditions
ConditionsYield
With dmap; TEA for 6h; Ambient temperature;88%
2,3-dihydro-2H-furan
1191-99-7

2,3-dihydro-2H-furan

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
5754-34-7

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

2,2-dimethyl-4-[2-(tetrahydro-furan-2-yloxy)-ethyl]-[1,3]dioxolane

2,2-dimethyl-4-[2-(tetrahydro-furan-2-yloxy)-ethyl]-[1,3]dioxolane

Conditions
ConditionsYield
With indium(III) chloride; 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate at 20℃; for 3h;87%
With 1-butyl-3-methylimidazolium Tetrafluoroborate at 20℃; for 12h;75%
4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
5754-34-7

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

4-(dimethylamino)benzenesulfonyl chloride
19715-49-2

4-(dimethylamino)benzenesulfonyl chloride

rac-O-isopropylidene-3,4-dihydroxybutyl p-dimethylaminobenzenesulfonate

rac-O-isopropylidene-3,4-dihydroxybutyl p-dimethylaminobenzenesulfonate

Conditions
ConditionsYield
With pyridine at 4℃; for 72h; Tosylation;86%
4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
5754-34-7

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

4-(2-methanesulfonylethyl)-2,2-dimethyl-1,3-dioxolane

4-(2-methanesulfonylethyl)-2,2-dimethyl-1,3-dioxolane

Conditions
ConditionsYield
With triethylamine In dichloromethane at -5℃; for 2.5h; Inert atmosphere;84.1%
4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
5754-34-7

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

2-(2,2-dimethyl-1,3-dioxolan-4-yl)ethyl methanesulfonate
76099-47-3

2-(2,2-dimethyl-1,3-dioxolan-4-yl)ethyl methanesulfonate

Conditions
ConditionsYield
With triethylamine In dichloromethane at -5℃; for 2.5h; Inert atmosphere;84.1%
4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
5754-34-7

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

2-(phenylsulfonyl)tetrahydro-2H-pyran
96754-03-9

2-(phenylsulfonyl)tetrahydro-2H-pyran

2-[2-(2,2-Dimethyl-[1,3]dioxolan-4-yl)-ethoxy]-tetrahydro-pyran
120346-89-6

2-[2-(2,2-Dimethyl-[1,3]dioxolan-4-yl)-ethoxy]-tetrahydro-pyran

Conditions
ConditionsYield
With sodium hydrogencarbonate; magnesium bromide In tetrahydrofuran Ambient temperature; overnight (15-24 hrs);78%
4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
5754-34-7

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

N-3-benzoylthymine
4330-20-5

N-3-benzoylthymine

(RS)-1-[2-(2,2-dimethyl-[1,3]dioxolan-4-yl)ethyl]thymine
471256-49-2

(RS)-1-[2-(2,2-dimethyl-[1,3]dioxolan-4-yl)ethyl]thymine

Conditions
ConditionsYield
With polystyrene-triphenylphosphine; di-isopropyl azodicarboxylate In tetrahydrofuran at 20℃; Mitsunobu condensation;67%
4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
5754-34-7

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

3,3-dichloro-1,1,1,2,2-pentafluoropropane
422-56-0

3,3-dichloro-1,1,1,2,2-pentafluoropropane

1,3-dichloro-1,1,2,2,3-pentafluoropropane
507-55-1

1,3-dichloro-1,1,2,2,3-pentafluoropropane

perfluoro-2,5-dimethyl-3,6-dioxanonanoyl fluoride
2641-34-1

perfluoro-2,5-dimethyl-3,6-dioxanonanoyl fluoride

C16H13O6F17

C16H13O6F17

Conditions
ConditionsYield
With sodium fluoride at 20℃; for 20h;67%
4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
5754-34-7

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

4-chloro-2,3-dimethylpyridine-N-oxide
59886-90-7

4-chloro-2,3-dimethylpyridine-N-oxide

4-[2-(2,2-dimethyl-1,3-dioxolan-4-yl)ethoxy]-2,3-dimethylpyridine 1-oxide
1020733-19-0

4-[2-(2,2-dimethyl-1,3-dioxolan-4-yl)ethoxy]-2,3-dimethylpyridine 1-oxide

Conditions
ConditionsYield
Stage #1: 4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane With sodium hydride In dimethyl sulfoxide at 20℃; for 0.5h;
Stage #2: 4-chloro-2,3-dimethylpyridine-N-oxide In dimethyl sulfoxide at 60℃; for 2h;
63.8%
4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
5754-34-7

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

bis(2-propyl)-p-toluenesulfonyloxymethylphosphonate
35717-98-7

bis(2-propyl)-p-toluenesulfonyloxymethylphosphonate

[2-(2,2-dimethyl[1,3]dioxolan-4-yl)ethoxymethyl]-phosphonic acid diisopropyl ester
918795-56-9

[2-(2,2-dimethyl[1,3]dioxolan-4-yl)ethoxymethyl]-phosphonic acid diisopropyl ester

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 20℃; for 16h;59%
4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
5754-34-7

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

3,5-difluoro-N-(2-fluoro-4-iodophenyl)-2-nitroaniline
765962-75-2

3,5-difluoro-N-(2-fluoro-4-iodophenyl)-2-nitroaniline

3-[2-(2,2-dimethyl-1,3-dioxolan-4-yl)ethoxy]-5-fluoro-N-(2-fluoro-4-iodophenyl)-2-nitroaniline
1084333-27-6

3-[2-(2,2-dimethyl-1,3-dioxolan-4-yl)ethoxy]-5-fluoro-N-(2-fluoro-4-iodophenyl)-2-nitroaniline

Conditions
ConditionsYield
Stage #1: 4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane With sodium hydride In tetrahydrofuran for 0.166667h;
Stage #2: 3,5-difluoro-N-(2-fluoro-4-iodophenyl)-2-nitroaniline In tetrahydrofuran for 0.5h;
59%
4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
5754-34-7

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

Methacryloyl chloride
920-46-7

Methacryloyl chloride

2-(2,2-dimethyl-1,3-dioxolane-4-yl)ethyl methacrylate

2-(2,2-dimethyl-1,3-dioxolane-4-yl)ethyl methacrylate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 15h; Inert atmosphere;58.4%
4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
5754-34-7

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

2,4-Dinitrofluorobenzene
70-34-8

2,4-Dinitrofluorobenzene

(+/-)-1,2-O-isopropylydene-4-(2,4-dinitrophenyloxy)-1,2-butanediol
40742-25-4

(+/-)-1,2-O-isopropylydene-4-(2,4-dinitrophenyloxy)-1,2-butanediol

Conditions
ConditionsYield
With triethylamine at 25℃; for 6h;58%
4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
5754-34-7

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

4-(2-iodoethyl)-2,2-dimethyl-1,3-dioxolane
98095-37-5

4-(2-iodoethyl)-2,2-dimethyl-1,3-dioxolane

Conditions
ConditionsYield
With 1H-imidazole; iodine; triphenylphosphine at 0 - 20℃; Darkness;49%
With 1H-imidazole; iodine; triphenylphosphine In dichloromethane at 0 - 20℃; for 0.666667h; Sealed tube; Inert atmosphere;44%
Multi-step reaction with 2 steps
1: Et3N / CH2Cl2
2: NaI; K2CO3
View Scheme
4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
5754-34-7

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

isopropylidene ketal of rac-3,4-dihydroxybutyl bromide
89942-18-7

isopropylidene ketal of rac-3,4-dihydroxybutyl bromide

Conditions
ConditionsYield
With bromine; triphenylphosphine In N,N-dimethyl-formamide for 1h; Ambient temperature;48%
With Bromoform; triethylamine; triphenylphosphine In dichloromethane at 0℃; for 20h;47.8%
Multi-step reaction with 2 steps
1: triethylamine / dichloromethane / 2.5 h / -5 °C / Inert atmosphere
2: magnesium bromide ethyl etherate / diethyl ether / Inert atmosphere
View Scheme
4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
5754-34-7

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

piperidinophosphoramidic dichloride

piperidinophosphoramidic dichloride

[2-(2,2-dimethyl-1,3-dioxolan-4-yl)ethyl] piperidinophosphoramidate

[2-(2,2-dimethyl-1,3-dioxolan-4-yl)ethyl] piperidinophosphoramidate

Conditions
ConditionsYield
With n-butyllithium In tetrahydrofuran43%
4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
5754-34-7

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

2-fluro-4-iodoaniline
29632-74-4

2-fluro-4-iodoaniline

2,4,6-trifluorobenzonitrile
96606-37-0

2,4,6-trifluorobenzonitrile

2-[2-(2,2-dimethyl-1,3-dioxolan-4-yl)ethoxy]-4-fluoro-6-[(2-fluoro-4-iodophenyl)amino]benzonitrile
1084333-29-8

2-[2-(2,2-dimethyl-1,3-dioxolan-4-yl)ethoxy]-4-fluoro-6-[(2-fluoro-4-iodophenyl)amino]benzonitrile

Conditions
ConditionsYield
Stage #1: 4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane; 2,4,6-trifluorobenzonitrile With sodium hydride In tetrahydrofuran at 20℃; for 1h;
Stage #2: 2-fluro-4-iodoaniline With potassium tert-butylate at 20℃; for 3h;
32%
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