3,4'-Oxydianiline supplier | CasNO.2657-87-6

Name
3,4'-Oxydianiline
EINECS 220-190-0
CAS No. 2657-87-6
Article Data9
CAS DataBase
Density 1.216 g/cm³
Solubility
Melting Point 67-71 °C(lit.)
Formula C₁₂H₁₂N₂O
Boiling Point 384.7 °C at 760 mmHg
Molecular Weight 200.24
Flash Point 209.9 °C
Transport Information
Appearance light brown powder
Safety 26-36
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms 3,4'-DAPE;3,4'-Diaminodiphenyl ether;3,4'-Oxydiphenylamine;3-Aminophenyl 4-aminophenyl ether;4,3'-Diaminodiphenyl oxide;
PSA 61.27000
LogP 3.80570

Synthetic route

: 100-00-5
4-chlorobenzonitrile

: 591-27-5
m-Hydroxyaniline

: 2657-87-6
3,4'-diaminodiphenyl ether

Conditions

Conditions	Yield
Stage #1: 4-chlorobenzonitrile; m-Hydroxyaniline With potassium carbonate; sodium hydrogensulfite In N,N-dimethyl-formamide at 100 - 120℃; for 10h; Inert atmosphere; Stage #2: With iron(III) chloride; 5%-palladium/activated carbon; hydrogen at 60 - 80℃; under 3750.38 Torr; for 2h; Autoclave;	96.1%

: 591-27-5
m-Hydroxyaniline

: 540-37-4
p-aminoiodobenzene

: 2657-87-6
3,4'-diaminodiphenyl ether

Conditions

Conditions	Yield
With 2-Picolinic acid; potassium phosphate; copper(l) iodide In dimethyl sulfoxide at 80℃; for 24h; Inert atmosphere;	54%

: 2914-72-9
1-nitro-3-(4-nitrophenoxy)benzene

: 2657-87-6
3,4'-diaminodiphenyl ether

Conditions

Conditions	Yield
With hydrogenchloride; tin

: 60732-27-6
4-(3-nitrophenoxy)phenylamine

: 2657-87-6
3,4'-diaminodiphenyl ether

Conditions

Conditions	Yield
With hydrazine

: 1124-31-8
potassium 4-nitrophenolate

: 2657-87-6
3,4'-diaminodiphenyl ether

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: copper-powder / 150 °C 2: tin; aqueous hydrochloric acid View Scheme

: 350-46-9
4-Fluoronitrobenzene

: 2657-87-6
3,4'-diaminodiphenyl ether

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: copper-powder / 150 °C 2: tin; aqueous hydrochloric acid View Scheme

: 5220-49-5
3-amino-cyclohex-2-enone

: 2657-87-6
3,4'-diaminodiphenyl ether

: 22528-34-3
3-amino-4'-nitrodiphenyl ether

: 2657-87-6
3,4'-diaminodiphenyl ether

Conditions

Conditions	Yield
With 0.5% Pd on alumina; hydrogen In N,N-dimethyl-formamide at 30℃; for 7h; Green chemistry;	> 99.9 %Spectr.

: 2657-87-6
3,4'-diaminodiphenyl ether

: 106-89-8
epichlorohydrin

: 129998-27-2
N,N,N',N'-tetraglycidyl-3,4'-diaminodiphenyl ether

Conditions

Conditions	Yield
With tetra(n-butyl)ammonium hydrogensulfate In water; toluene at 80℃; for 15h;	100%

: 2657-87-6
3,4'-diaminodiphenyl ether

: 91-56-5
indole-2,3-dione

: 3,3'-[oxybis[(3,1)-(4',1')phenylenenitrilo]]bis[1,3-dihydro-2H-indol-2-one]

Conditions

Conditions	Yield
With acetic acid In ethanol for 28h; Heating;	91%
In water at 20℃; for 45h;	80%
In ethanol Heating;

: 2657-87-6
3,4'-diaminodiphenyl ether

: 642-31-9
9-anthracene aldehyde

: 1251936-16-9
(E)-N-(anthracen-10-ylmethylene)-3-(4-[(E)-anthracen-10-ylmethyleneamino]phenoxy)benzeneamine

Conditions

Conditions	Yield
In ethanol Reflux;	88%

: 2657-87-6
3,4'-diaminodiphenyl ether

: 322474-21-5
N,N'-bis-Boc-S-methyl-isothiourea

: 3,4’-bis[2,3-di(tert-butoxycarbonyl)guanidino]diphenylether

Conditions

Conditions	Yield
With triethylamine; mercury dichloride In dichloromethane at 0 - 20℃;	87%

: 2657-87-6
3,4'-diaminodiphenyl ether

: 1107-00-2
4,4'-(1,1,1,3,3,3-hexafluoroisopropylidene)diphthalic anhydride

: 104-10-9
2-(4'-aminophenyl)ethyl alcohol

linear fluorine-containing hydroxy-terminated polyimide: linear fluorine-containing hydroxy-terminated polyimide

Conditions

Conditions	Yield
Stage #1: 3,4'-diaminodiphenyl ether; 4,4'-(1,1,1,3,3,3-hexafluoroisopropylidene)diphthalic anhydride; 2-(4'-aminophenyl)ethyl alcohol In 1-methyl-pyrrolidin-2-one at 20℃; for 12h; Stage #2: In para-xylene at 180℃; for 6h; Further stages.;	83%

...Expand

: 2657-87-6
3,4'-diaminodiphenyl ether

: 2,3',4,5',6-pentabromo-3,4'-diaminodiphenyl ether

Conditions

Conditions	Yield
With bromine In acetic acid at 35℃; for 1h;	81%

: 2657-87-6
3,4'-diaminodiphenyl ether

: 145013-05-4
tert-butyl N-({[(tert-butoxy)carbonyl]amino}methanethioyl)carbamate

: 3-amino-{4'-[2,3-di(tert-butoxycarbonyl)]guanidino}diphenyl ether

Conditions

Conditions	Yield
With triethylamine; mercury dichloride In dichloromethane at 0 - 20℃;	77%
With triethylamine; mercury dichloride In dichloromethane at 25℃; for 12h;	51%

: 1037587-67-9
N-tert-butoxycarbonyl-N’-phenylthiourea

: 2657-87-6
3,4'-diaminodiphenyl ether

: 3-amino-4'-[2-(tert-butoxycarbonyl)-3-phenylguanidino]diphenyl ether

Conditions

Conditions	Yield
With triethylamine; mercury dichloride In dichloromethane at 0 - 20℃; for 4h;	76%

: 2657-87-6
3,4'-diaminodiphenyl ether

: 52871-22-4
3-nitro-4-chloro-1,8-naphthalene dicarboxylic acid anhydride

: C36H18N4O11

Conditions

Conditions	Yield
In ethanol; N,N-dimethyl-formamide for 0.5h; Heating;	75%

: 2657-87-6
3,4'-diaminodiphenyl ether

: 145013-05-4
tert-butyl N-({[(tert-butoxy)carbonyl]amino}methanethioyl)carbamate

A: 3-amino-{4'-[2,3-di(tert-butoxycarbonyl)]guanidino}diphenyl ether

B: C23H30N4O5

Conditions

Conditions	Yield
With triethylamine; mercury dichloride In dichloromethane at 0 - 20℃;	A 75% B 25%

...Expand

: 16533-70-3
2-(3,5-dinitrobenzamido)acetic acid

: 2657-87-6
3,4'-diaminodiphenyl ether

: 1037570-01-6
C30H22N8O13

Conditions

Conditions	Yield
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃;	70%

: 2657-87-6
3,4'-diaminodiphenyl ether

: 98-88-4
benzoyl chloride

: 1037569-97-3
C26H20N2O3

Conditions

Conditions	Yield
With (+/-)-propylene oxide In tetrahydrofuran at 20℃;	70%

: 2657-87-6
3,4'-diaminodiphenyl ether

: 52071-01-9
-glycin

: 1037570-05-0
C40H44N6O13

Conditions

Conditions	Yield
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃;	69%

: 2657-87-6
3,4'-diaminodiphenyl ether

: 31384-90-4
hippuroyl-Gly-Gly

: 1037570-06-1
C38H38N8O9

Conditions

Conditions	Yield
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃;	68%

: 2657-87-6
3,4'-diaminodiphenyl ether

: 99-33-2
3,5-dinitrobenoyl chloride

: 1037569-98-4
C26H16N6O11

Conditions

Conditions	Yield
With (+/-)-propylene oxide In tetrahydrofuran at 20℃;	68%

: 2657-87-6
3,4'-diaminodiphenyl ether

: 173300-83-9
2-thioxo-imidazolidine-1,3-dicarboxylic acid di-tert-butyl ester

: 3,4’-bis[2,3-di(tert-butoxycarbonyl)-2-iminoimidazolidino]diphenyl ether

Conditions

Conditions	Yield
With triethylamine; mercury dichloride In dichloromethane at 0 - 20℃;	68%

: 2657-87-6
3,4'-diaminodiphenyl ether

: N-(4-chloro-3-trifluoromethylphenyl)-N’-(tert-butoxycarbonyl)thiourea

: 3-amino-4'-[2-(tert-butoxycarbonyl)-3-(4-chloro-3-trifluoromethyl)guanidino]diphenyl ether

Conditions

Conditions	Yield
With triethylamine; mercury dichloride In dichloromethane at 0 - 20℃; for 4h;	68%

: 2657-87-6
3,4'-diaminodiphenyl ether

: 2-hydroxy-3-(morpholinomethyl)benzaldehyde

: 2-((3-(4-(2-hydroxy-3-(morpholinomethyl)benzylideneamino)phenoxy)phenylimino)methyl)-6-(morpholinomethyl)phenol

Conditions

Conditions	Yield
In ethanol Reflux;	68%

: 2657-87-6
3,4'-diaminodiphenyl ether

: 1037569-82-6
N-[N-(3,5-dinitro-benzoyl)-glycyl]-glycine

: 1037570-04-9
C34H28N10O15

Conditions

Conditions	Yield
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃;	66%

: 13081-18-0
ethyl-3,3,3-trifluoropyruvate

: 2657-87-6
3,4'-diaminodiphenyl ether

: 1400992-23-5
6-(4-aminophenoxy)-3-hydroxy-3-(trifluoromethyl)indolin-2-one

Conditions

Conditions	Yield
In 1,2-dichloro-benzene at 20 - 150℃; for 0.416667h; Microwave irradiation;	66%

: 1145-32-0
N-(N'-benzoyl-2-aminoethanoyl)-2-aminoethanoic acid

: 2657-87-6
3,4'-diaminodiphenyl ether

: 1037570-03-8
C34H32N6O7

Conditions

Conditions	Yield
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃;	65%

: 2657-87-6
3,4'-diaminodiphenyl ether

: 1037569-83-7
N-(3,5-dinitro-benzoyl)-glycyl=>glycyl=>glycine

: 1037570-07-2
C38H34N12O17

Conditions

Conditions	Yield
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃;	65%

: 495-69-2
Hippuric Acid

: 2657-87-6
3,4'-diaminodiphenyl ether

: 1037570-00-5
C30H26N4O5

Conditions

Conditions	Yield
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃;	64%

: 2657-87-6
3,4'-diaminodiphenyl ether

: 4521-61-3
3,4,5-Trimethoxybenzoyl chloride

: 1037569-99-5
C32H32N2O9

Conditions

Conditions	Yield
With (+/-)-propylene oxide In tetrahydrofuran at 20℃;	64%

: 2657-87-6
3,4'-diaminodiphenyl ether

: 40915-27-3
(3,4,5-trimethoxybenzoylamino)acetic acid

: 1037570-02-7
C36H38N4O11

Conditions

Conditions	Yield
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃;	63%

: 2657-87-6
3,4'-diaminodiphenyl ether

: 52071-02-0
-glycin

: 1037570-08-3
C44H50N8O15

Conditions

Conditions	Yield
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃;	61%

: 1037569-77-9
[2-(cyclohexanecarbonylamino)acetylamino]acetic acid

: 2657-87-6
3,4'-diaminodiphenyl ether

: 1037569-78-0
C34H44N6O7

Conditions

Conditions	Yield
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃;	58%

: 2657-87-6
3,4'-diaminodiphenyl ether

: 1037569-82-6
N-[N-(3,5-dinitro-benzoyl)-glycyl]-glycine

: 1037569-79-1
C23H20N6O8

Conditions

Conditions	Yield
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃; for 15h;	56%

: 2657-87-6
3,4'-diaminodiphenyl ether

: 32407-06-0
5-[(3,4,5-trimethoxybenzoyl)amino]pentanoic acid

: 1037569-76-8
C42H50N4O11

Conditions

Conditions	Yield
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃;	55%

3,4'-Oxydianiline Chemical Properties

Product Name: 3,4'-Oxydianiline (CAS NO.2657-87-6)

Molecular Formula: C₁₂H₁₂N₂O
Molecular Weight: 200.24g/mol
Mol File: 2657-87-6.mol
EINECS: 220-190-0
Melting Point: 67-71 °C(lit.)
Boiling point: 384.7 °C at 760 mmHg
Flash Point: 209.9 °C
Density: 1.216 g/cm³
Index of Refraction: 1.665
Molar Refractivity: 61.16 cm³
Molar Volume: 164.5 cm³
Surface Tension: 55.9 dyne/cm
Enthalpy of Vaporization: 63.34 kJ/mol
Vapour Pressure: 4E-06 mmHg at 25°C
XLogP3-AA: 2.2
H-Bond Donor: 2
H-Bond Acceptor: 3
Structure Descriptors of 3,4'-Oxydianiline (CAS NO.2657-87-6):
IUPAC Name: 3-(4-aminophenoxy)aniline
Canonical SMILES: C1=CC(=CC(=C1)OC2=CC=C(C=C2)N)N
InChI: InChI=1S/C12H12N2O/c13-9-4-6-11(7-5-9)15-12-3-1-2-10(14)8-12/h1-8H,13-14H2
InChIKey: ZBMISJGHVWNWTE-UHFFFAOYSA-N
Product Categories: Biphenyl & Diphenyl ether; Amines; Miscellaneous; Diphenyl Ethers (for High-Performance Polymer Research); Functional Materials; Reagent for High-Performance Polymer Research; Amine Monomers; Monomers; Primary Amines

3,4'-Oxydianiline Safety Profile

Safety Information of 3,4'-Oxydianiline (CAS NO.2657-87-6):
Hazard Codes: Xi Irritant
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
WGK Germany: 3

3,4'-Oxydianiline Specification

3,4'-Oxydianiline , its CAS NO. is 2657-87-6, the synonyms are 3-(4-Aminophenoxy)aniline ; 3-(4-Aminophenoxy)phenylamine ; 3-Aminophenyl 4-aminophenyl ether ; Benzenamine, 3-(4-aminophenoxy)- .

Product Name

3,4'-Oxydianiline

Synthetic route

3,4'-Oxydianiline Chemical Properties

3,4'-Oxydianiline Safety Profile

3,4'-Oxydianiline Specification

Related Products

Hot Products