(3-Amino-pyridin-2-yl)-acetic acid

The 3-Amino-2-pyridineacetic acid, with the CAS registry number 80352-63-2, is also known as 2-Pyridineacetic acid, 3-amino-. This chemical's molecular formula is C₇H₈N₂O₂ and molecular weight is 152.15. What's more, its systematic name is (3-Amino-2-pyridinyl)acetic acid.

Physical properties of 3-Amino-2-pyridineacetic acid are: (1)ACD/LogP: -0.732; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -2.30; (4)ACD/LogD (pH 7.4): -3.62; (5)ACD/BCF (pH 5.5): 1.00; (6)ACD/BCF (pH 7.4): 1.00; (7)ACD/KOC (pH 5.5): 1.00; (8)ACD/KOC (pH 7.4): 1.00; (9)#H bond acceptors: 4; (10)#H bond donors: 3; (11)#Freely Rotating Bonds: 3; (12)Polar Surface Area: 76.21 Å²; (13)Index of Refraction: 1.624; (14)Molar Refractivity: 39.694 cm³; (15)Molar Volume: 112.38 cm³; (16)Polarizability: 15.736×10^-24cm³; (17)Surface Tension: 70.5 dyne/cm; (18)Density: 1.354 g/cm³; (19)Flash Point: 190.261 °C; (20)Enthalpy of Vaporization: 67.557 kJ/mol; (21)Boiling Point: 390.985 °C at 760 mmHg; (22)Vapour Pressure: 0 mmHg at 25°C.

Preparation of 3-Amino-2-pyridineacetic acid: this chemical can be prepared by 2-bis(benzyloxycarbonyl)methyl-3-nitropyridine. This reaction will need reagent hydrogen and solvent ethanol with the reaction time of 4 hours. This reaction will also need catalyst 10% palladised charcoal. The yield is about 80%.

Uses of 3-Amino-2-pyridineacetic acid: it can be used to produce 2-methyl-pyridin-3-ylamine by heating. It will need solvent ethanol with the reaction time of 5 hours. The yield is about 86%.

You can still convert the following datas into molecular structure:
(1)SMILES: c1cc(c(nc1)CC(=O)O)N
(2)Std. InChI: InChI=1S/C7H8N2O2/c8-5-2-1-3-9-6(5)4-7(10)11/h1-3H,4,8H2,(H,10,11)
(3)Std. InChIKey: MWRPQJISCIAKFV-UHFFFAOYSA-N