• Name

  3-BROMO-2-METHYLPROPIONIC ACID

• EINECS
• CAS No. 56970-78-6
• Article Data12
• CAS DataBase
• Density 1.625g/cm³
• Solubility
• Melting Point 173 °C (decomp)
• Formula C4H7 Br O2
• Boiling Point 230.5°Cat760mmHg
• Molecular Weight 167.002
• Flash Point 93.2°C
• Transport Information
• Appearance
• Safety
• Risk Codes
• Molecular Structure
• Hazard Symbols
• Synonyms Propionicacid, 3-bromo-2-methyl- (6CI,7CI); (?à)-3-Bromo-2-methylpropionic acid;3-Bromo-2-methylpropionic acid; NSC 201472; b-Bromoisobutanoic acid
• PSA 37.30000
• LogP 1.10200

Synthetic route

79-41-4

poly(methacrylic acid)

56970-78-6

3-bromo-2-methylpropionic acid

Conditions

Conditions	Yield
With bromine; acetic acid	91%
With hydrogen bromide In water at 60 - 65℃; Inert atmosphere;	87.2%
With hydrogen bromide at 20℃; for 2h;	70%

20609-71-6

3-bromo-2-methyl-propionic acid methyl ester

56970-78-6

3-bromo-2-methylpropionic acid

Conditions

Conditions	Yield
With bis(tri-n-butyltin)oxide In toluene at 111℃; for 48h;	60%

56970-78-6

3-bromo-2-methylpropionic acid

26473-47-2

2-methyl-3-sulfanylpropanoic acid

Conditions

Conditions	Yield
With copper(l) iodide; sodium hydrogensulfide; tetrabutylammomium bromide In water at 65 - 75℃; Reagent/catalyst; Solvent; Inert atmosphere;	92.6%
With sodium sulfide; water; sodium carbonate

56970-78-6

3-bromo-2-methylpropionic acid

654-70-6

4-amino-2-trifluoromethylbenzonitrile

3-bromo-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-methylpropanamide

Conditions

Conditions	Yield
With thionyl chloride; trimethylamine	91%
Stage #1: 3-bromo-2-methylpropionic acid With thionyl chloride In tetrahydrofuran for 2h; Inert atmosphere; Stage #2: 4-amino-2-trifluoromethylbenzonitrile With triethylamine In tetrahydrofuran at 50℃; for 2h; Inert atmosphere;

67-56-1

methanol

56970-78-6

3-bromo-2-methylpropionic acid

20609-71-6

3-bromo-2-methyl-propionic acid methyl ester

Conditions

Conditions	Yield
With sulfuric acid	90%

56970-78-6

3-bromo-2-methylpropionic acid

71271-28-8

3-bromo-2-methylpropanoyl chloride

Conditions

Conditions	Yield
With thionyl chloride for 4h; Heating;	77%
With thionyl chloride
With thionyl chloride

56970-78-6

3-bromo-2-methylpropionic acid

381-80-6

3-bromo-1,1,1-trifluoro-2-methylpropane

Conditions

Conditions	Yield
With sulfur tetrafluoride; water for 24h; Autoclave;	60%

56970-78-6

3-bromo-2-methylpropionic acid

1823-54-7

α-methyl-β-propiolactone

Conditions

Conditions	Yield
With sodium hydroxide In chloroform for 2h; Cyclization;	42%

108-02-1

captamine

56970-78-6

3-bromo-2-methylpropionic acid

α-methyl carboxybetaine disulfide

Conditions

Conditions	Yield
Stage #1: 3-bromo-2-methylpropionic acid With sodium carbonate In ethanol; water at 1℃; for 20h; Stage #2: captamine In ethanol at 40℃; for 72h; Inert atmosphere;	26%

56970-78-6

3-bromo-2-methylpropionic acid

<(32)S>-2-methyl-3-mercaptopropanoic acid

Conditions

Conditions	Yield
With sodium hydroxide; (32)S-hydrogen sulfide at 95℃; for 3h;	14%

529-36-2

1-Naphthalenethiol

56970-78-6

3-bromo-2-methylpropionic acid

β-[1]naphthylsulfanyl-isobutyric acid

Conditions

Conditions	Yield
With sodium hydroxide

56970-78-6

3-bromo-2-methylpropionic acid

79-41-4

poly(methacrylic acid)

Conditions

Conditions	Yield
With water
With sodium hydroxide at 20℃;
With barium dihydroxide

56970-78-6

3-bromo-2-methylpropionic acid

68-11-1

mercaptoacetic acid

34914-38-0

β-carboxymethylsulfanyl-isobutyric acid

Conditions

Conditions	Yield
With sodium hydroxide

56970-78-6

3-bromo-2-methylpropionic acid

123-31-9

hydroquinone

β-(4-methoxy-phenoxy)-isobutyric acid

Conditions

Conditions	Yield
With potassium hydroxide; potassium carbonate

56970-78-6

3-bromo-2-methylpropionic acid

91-60-1

2-Naphthalenethiol

3-((naphthalen-2-yl)thio)-2-methylpropanoic acid

Conditions

Conditions	Yield
With sodium hydroxide

56970-78-6

3-bromo-2-methylpropionic acid

52-89-1

l-cysteine hydrochloride

6852-42-2

S-(2-D,L-carboxy-n-propyl)-L-cysteine

Conditions

Conditions	Yield
With sodium hydroxide In ethanol

67-56-1

methanol

56970-78-6

3-bromo-2-methylpropionic acid

91-59-8

naphthalen-2-ylamine

1148-94-3

2-Methyl-3--propionsaeure-methylester

Conditions

Conditions	Yield
(i) NaOnBu, nBuOH, (ii) /BRN= 1098229/, HCl; Multistep reaction;

...Expand

56970-78-6

3-bromo-2-methylpropionic acid

furan-2,3,5(4H)-trione pyridine (1:1)

A

79-41-4

poly(methacrylic acid)

B

10035-10-6, 12258-64-9

hydrogen bromide

...Expand

56970-78-6

3-bromo-2-methylpropionic acid

barytes

barytes

A

79-41-4

poly(methacrylic acid)

B

10035-10-6, 12258-64-9

hydrogen bromide

...Expand

56970-78-6

3-bromo-2-methylpropionic acid

zinc di-(2-methyl-3-bromopropionate)

Conditions

Conditions	Yield
With zinc(II) oxide In water

56970-78-6

3-bromo-2-methylpropionic acid

40145-08-2

3-bromo-2-methyl propan-1-ol

Conditions

Conditions	Yield
Stage #1: 3-bromo-2-methylpropionic acid With dimethylsulfide borane complex In dichloromethane at -10 - 20℃; for 20h; Stage #2: With hydrogenchloride; dihydrogen peroxide In dichloromethane; water at 20℃; for 2h;	6.6 g

methyl 6-(trifluoromethyl)-1H-indole-2-carboxylate

56970-78-6

3-bromo-2-methylpropionic acid

C15H14F3NO4

Conditions

Conditions	Yield
Stage #1: methyl 6-(trifluoromethyl)-1H-indole-2-carboxylate With sodium hydride In N,N-dimethyl-formamide at 20℃; for 0.25h; Inert atmosphere; Stage #2: 3-bromo-2-methylpropionic acid In N,N-dimethyl-formamide at 20℃; for 16h; Inert atmosphere;

56970-78-6

3-bromo-2-methylpropionic acid

3-(3,5-bis(trifluoromethyl)phenyl)-1H-pyrazole

3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-pyrazol-1-yl)-2-methylpropanoic acid

Conditions

Conditions	Yield
With caesium carbonate In N,N-dimethyl-formamide at 0 - 70℃; for 2h;	45 mg

3-Bromoisobutyric acid Chemical Properties