-
Name
4-Aminoantipyrine
- EINECS 201-452-3
- CAS No. 83-07-8
- Article Data37
- CAS DataBase
- Density 1.207 g/cm3
- Solubility water: 0.1 g/mL, clear
- Melting Point 105-110 °C(lit.)
- Formula C11H13N3O
- Boiling Point 309 °C at 760 mmHg
- Molecular Weight 203.244
- Flash Point 140.7 °C
- Transport Information
- Appearance Amber crystalline powder
- Safety 26-36-36/37/39
- Risk Codes 22-36/37/38-20/21/22
-
Molecular Structure
-
Hazard Symbols
Xn
- Synonyms Antipyrine,4-amino- (8CI);1,2-Dihydro-1,5-dimethyl-2-phenyl-4-amino-3H-pyrazol-3-one;4-AAP;4-Amino-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one;4-Amino-1,5-dimethyl-2-phenylpyrazolin-3-one;4-Amino-2,3-dimethyl-1-phenyl-5-pyrazolone;Aminoantipyrine;Ampyrone;NSC 60242;1-Phenyl-2,3-dimethyl-4-aminopyrazol-5-one;
- PSA 52.95000
- LogP 1.64780
4-AMINOANTIPYRINE Chemical Properties
IUPAC Name: 4-Aminoantipyrine
The MF of 4-Aminoantipyrine (83-07-8) is C11H13N3O.
The MW of 4-Aminoantipyrine (83-07-8) is 203.24.
Synonyms of 4-Aminoantipyrine (83-07-8): 4-Amino-1,2-dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one ; 4-Amino-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one ; 4-Amino-1,5-dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-one
Product Categories: Drug bulk;Pyridines, Pyrimidines, Purines and Pteredines
Form: amber crystalline powder
Index of Refraction: 1.606
EINECS: 201-452-3
Density: 1.207 g/ml
Flash Point: 140.7 °C
Boiling Point: 309 °C
Melting Point: 107-109 °C
Storage temp: Store at RT
Water Solubility: 500 g/L (20 ºC)
Merck: 14,591
BRN: 181635
Stability: Stable
4-AMINOANTIPYRINE Uses
4-Aminoantipyrine (83-07-8) is pharmaceutical intermediates analgin used to test alcohol and amines, phenols measured air and water.
4-AMINOANTIPYRINE Toxicity Data With Reference
| 1. | mmo-sat 5 µmol/plate | MUREAV Mutation Research. 206 (1988),317. | ||
| 2. | dnr-esc 312 µg/well | MUREAV Mutation Research. 133 (1984),161. | ||
| 3. | orl-rat LD50:1700 mg/kg | BCFAAI Bollettino Chimico Farmaceutico. 117 (1978),638. | ||
| 4. | ipr-rat LD50:1200 mg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 99 (1950),171. | ||
| 5. | orl-mus LD50:800 mg/kg | CCCCAK Collection of Czechoslovak Chemical Communications. 47 (1982),636. | ||
| 6. | ipr-mus LD50:270 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 10 (1960),820. |
4-AMINOANTIPYRINE Consensus Reports
Reported in EPA TSCA Inventory.
4-AMINOANTIPYRINE Safety Profile
Poison by intraperitoneal route. Moderately toxic by ingestion. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating vapors.
Safety information of 4-Aminoantipyrine (83-07-8):
Hazard Codes 
Xn
Risk Statements
36/37/38 Irritating to eyes, respiratory system and skin
20/21/22 Harmful by inhalation, in contact with skin and if swallowed
Safety Statements
26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36/37/39 Wear suitable protective clothing, gloves and eye/face protection
WGK Germany 3
RTECS CD2480000
F 8-9-23
Hazard Note Harmful
HS Code 29331190
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