4-Chloro-3-methoxy-2-methylpyridine N-oxide

This chemical is called 4-Chloro-3-methoxy-2-methylpyridine N-oxide, and its CAS registry number is 122307-41-9. With the molecular formula of C₇H₈ClNO₂, its product categories are API Intermediates; Bases & Related Reagents; Nucleotides; Heterocyclic Building Blocks;Pyridines. Additionally, this chemical should be sealed in the cool and dry place, away from oxides, water and heat.

Other characteristics of the 4-Chloro-3-methoxy-2-methylpyridine N-oxide can be summarised as followings: (1)ACD/LogP: -0.11; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -0.11; (4)ACD/LogD (pH 7.4): -0.11; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 20.73; (8)ACD/KOC (pH 7.4): 20.73; (9)#H bond acceptors: 3; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 1; (12)Polar Surface Area: 33.34 Å²; (13)Index of Refraction: 1.527; (14)Molar Refractivity: 42.67 cm³; (15)Molar Volume: 138.7 cm³; (16)Polarizability: 16.91×10^-24cm³; (17)Surface Tension: 37.1 dyne/cm; (18)Density: 1.25 g/cm³; (19)Flash Point: 163.2 °C; (20)Enthalpy of Vaporization: 56.7 kJ/mol; (21)Boiling Point: 346.2 °C at 760 mmHg; (22)Vapour Pressure: 0.000117 mmHg at 25°C.

Production method of this chemical: The 4-Chloro-3-methoxy-2-methylpyridine N-oxide could be obtained by the reactant of 4-chloro-3-methoxy-2-methylpyridine. This reaction needs the reagents of 30 percent aq. H₂O₂, AcOH. The yield is 90 %. In addition, this reaction should be taken for 24 hours at the temperature of 90 °C.

Uses of this chemical: The 4-Chloro-3-methoxy-2-methylpyridine N-oxide could react with methanol to obtain the 3,4-dimethoxy-2-methylpyridine N-oxide. This reaction needs the reagent of NaOMe. The yield is 91 %. In addition, this reaction should be taken for 18 hours.

When you are using this chemical, please be cautious about it as the following: This chemical is irritating to eyes, respiratory system and skin. You should wear suitable protective clothing if you use it. In case of contacting with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure: 
1.SMILES: [O-][n+]1ccc(Cl)c(OC)c1C
2.InChI: InChI=1/C7H8ClNO2/c1-5-7(11-2)6(8)3-4-9(5)10/h3-4H,1-2H3
3.InChIKey: TWXMQDRFBLSXFN-UHFFFAOYAT