Product Name

  • Name

    4-Hydroxypipecolic acid

  • EINECS
  • CAS No. 14228-16-1
  • Article Data10
  • CAS DataBase
  • Density 1.299g/cm3
  • Solubility
  • Melting Point 250 °C
  • Formula C6H11NO3
  • Boiling Point 346°Cat760mmHg
  • Molecular Weight 145.158
  • Flash Point 163°C
  • Transport Information
  • Appearance
  • Safety
  • Risk Codes
  • Molecular Structure Molecular Structure of 14228-16-1 (4-Hydroxypipecolic acid)
  • Hazard Symbols
  • Synonyms 4-Hydroxy-2-piperidinecarboxylic acid
  • PSA 69.56000
  • LogP -0.48730

4-Hydroxypipecolic acid Chemical Properties

Molecular Structure of 4-Hydroxypipecolic acid (CAS NO.14228-16-1):

IUPAC Name: 4-Hydroxypiperidine-2-carboxylic acid 
Molecular Formula: C6H11NO3
Molecular Weight: 145.16 
Index of Refraction: 1.522
Molar Refractivity: 34.1 cm3
Molar Volume: 111.7 cm3
Surface Tension: 54.8 dyne/cm
Density: 1.299 g/cm3
Flash Point: 163 °C
Enthalpy of Vaporization: 68.34 kJ/mol
Boiling Point: 346 °C at 760 mmHg
Vapour Pressure: 3.72E-06 mmHg at 25 °C
Product Categories: pharmacetical
Canonical SMILES: C1CNC(CC1O)C(=O)O
InChI: InChI=1S/C6H11NO3/c8-4-1-2-7-5(3-4)6(9)10/h4-5,7-8H,1-3H2,(H,9,10)
InChIKey: KRHNXNZBLHHEIU-UHFFFAOYSA-N

4-Hydroxypipecolic acid Uses

 4-Hydroxypipecolic acid (CAS NO.14228-16-1) is used as an N-methyl-D-aspartate receptors agonist.

4-Hydroxypipecolic acid Specification

 4-Hydroxypipecolic acid (CAS NO.14228-16-1), its Synonyms are 4-Hydroxy-2-piperidinecarboxylic acid ; t-Hpis ; trans-4-Hydroxy-(S)-pipecolic acid-4-sulfate ; 2-Piperidinecarboxylic acid, 4-hydroxy- .
 A new method for the determination of naturally occurring imino acids in plants which comprises the formation of dinitrophenyl derivatives and their measurement by HPLC was devised. The determination limits were 100 pmol for 4-Hydroxypipecolic acid (HPA) and proline (Pro) and 10 pmol for pipecolic acid (Pip).

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