4-METHYL-1,3-OXAZOLE-5-CARBOXYLIC ACID

IUPAC Name: 4-methyl-1,3-oxazole-5-carboxylic acid
Molecular Formula: C₅H₅NO₃
Molecular Weight: 127.1 g/mol
Canonical SMILES: CC1=C(OC=N1)C(=O)O
InChI: InChI=1S/C5H5NO3/c1-3-4(5(7)8)9-2-6-3/h2H,1H3,(H,7,8)
Mol File: 2510-32-9.mol
Product Categories: Carboxylic Acids; Oxazoles, Isoxazoles & Benzoxazoles; HeterocyclicCompounds; Carboxylic Acids; Oxazoles, Isoxazoles & Benzoxazoles; Building Blocks; Heterocyclic Building Blocks; Oxazoles
XLogP3-AA: 0.6
H-Bond Donor: 1
H-Bond Acceptor: 4
Rotatable Bond Count: 1
Exact Mass: 127.026943
MonoIsotopic Mass: 127.026943
Topological Polar Surface Area: 63.3
Heavy Atom Count: 9
Complexity: 125
Index of Refraction: 1.514 
Molar Refractivity: 28.39 cm³ 
Molar Volume: 94.2 cm³ 
Polarizability: 11.25×10^-24cm³ 
Surface Tension: 53.7 dyne/cm 
Density: 1.348 g/cm³ 
Flash Point: 115.5 °C 
Enthalpy of Vaporization: 53.39 kJ/mol
Boiling Point: 267.3 °C at 760 mmHg 
Melting Point: 239 °C
Vapour Pressure of 4-Methyloxazole-5-carboxylic acid (CAS NO.2510-32-9): 0.00408 mmHg at 25 °C

 4-Methoxyoxazole-5-carboxylic Acid is used in the synthesis of highly selective α4β2-Nicotinic acetylcholine receptor agonists used in the treatment of cognitive disorders. It is also used in the synthesis of small molecule human FPR1 receptor antagonists.

Hazard Codes: Xi,Xn 
Risk Statements: 22-36/37/38 
R22: Harmful if swallowed.
 R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 22-26-36/37/39 
S22: Do not breathe dust. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
Hazard Note of 4-Methyloxazole-5-carboxylic acid (CAS NO.2510-32-9): Irritant

  4-Methyloxazole-5-carboxylic acid (CAS NO.2510-32-9), its Synonyms are 4-Methyl-5-oxazolecarboxylic acid
; 4-Methyl-oxazole-5-carboxylic acid ; 4-Methyl-1,3-oxazole-5-carboxylic acid ; 4-Methyl-1,3-oxazole-5-
carboxylic acid 95% ; 4-Methyl-1,3-oxazole-5-carboxylic acid ,97% .