6-Ethyl-3-oxa-6-azaoctanol supplier

Name
6-Ethyl-3-oxa-6-azaoctanol
EINECS 205-436-7
CAS No. 140-82-9
Article Data13
CAS DataBase
Density 0.939 g/cm³
Solubility
Melting Point
Formula C₈H₁₉NO₂
Boiling Point 234.7 °C at 760 mmHg
Molecular Weight 161.244
Flash Point 95.8 °C
Transport Information
Appearance colorless or light yellow liquid
Safety 23-24/25
Risk Codes 34
Molecular Structure
Hazard Symbols C
Synonyms Ethanol,2-(b-diethylaminoethoxy)- (3CI);2-(b-Diethylamino)ethoxyethanol;2-[2-(Diethylamino)ethoxy]ethanol;2-[2-(N,N-Diethylamino)ethoxy]ethanol;Diethyl[2-(2-hydroxyethoxy)ethyl]amine;NSC 163322;
PSA 32.70000
LogP 0.33710

Synthetic route

: 118591-58-5
5-tosyloxy-3-oxapentanol

: 109-89-7
diethylamine

: 140-82-9
2-[2-(diethylamino)ethoxy] ethanol

Conditions

Conditions	Yield
With potassium carbonate In 1,4-dioxane at 70℃;	42%

: 75-21-8
oxirane

: 100-37-8
2-(Diethylamino)ethanol

: 140-82-9
2-[2-(diethylamino)ethoxy] ethanol

Conditions

Conditions	Yield
at 100℃;
at 100℃;

: 628-89-7
2-(2-Chloroethoxy)ethanol

: 109-89-7
diethylamine

: 140-82-9
2-[2-(diethylamino)ethoxy] ethanol

: 14258-40-3
2-(2-chloroethoxy)ethyl ethanoate

: 109-89-7
diethylamine

: 140-82-9
2-[2-(diethylamino)ethoxy] ethanol

Conditions

Conditions	Yield
With ethanol at 125℃;

: 114188-38-4
Methyl-N,N-diethyldiglycollamat

: 140-82-9
2-[2-(diethylamino)ethoxy] ethanol

Conditions

Conditions	Yield
With lithium aluminium tetrahydride

: 100-37-8
2-(Diethylamino)ethanol

: 107-07-3
2-chloro-ethanol

: 140-82-9
2-[2-(diethylamino)ethoxy] ethanol

Conditions

Conditions	Yield
With sodium

: 100-35-6
2-(diethylamino)ethyl chloride

monosodium compound of ethylene glycol: monosodium compound of ethylene glycol

: 140-82-9
2-[2-(diethylamino)ethoxy] ethanol

Conditions

Conditions	Yield
With benzene

: 52432-72-1
Dorex

A: 5465-28-1
α-Ethyl-α-phenylbutyric acid

B: 140-82-9
2-[2-(diethylamino)ethoxy] ethanol

Conditions

Conditions	Yield
With sodium hydroxide at 100℃; for 3h;

: 75-07-0
acetaldehyde

: 929-06-6
2-(2-Aminoethoxy)ethanol

: 140-82-9
2-[2-(diethylamino)ethoxy] ethanol

Conditions

Conditions	Yield
With NaBH3CN In methanol; water
With NaBH3CN In methanol; water

: 52835-16-2
2-Heptadecafluorooctyl-oxirane

: 140-82-9
2-[2-(diethylamino)ethoxy] ethanol

: 99679-36-4
N,N-diethyl hydroxy-8 F-octyl-8 dioxa-3,6 octylamine

Conditions

Conditions	Yield
With sodium at 80 - 100℃;	60%

: 79-03-8
propionyl chloride

: 140-82-9
2-[2-(diethylamino)ethoxy] ethanol

: 868845-26-5
C11H23NO3

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 20℃; for 20h;	56%

: 19333-10-9
silicon (IV) phthalocyanine dichloride

: 140-82-9
2-[2-(diethylamino)ethoxy] ethanol

: bis{2-[2-(diethylamino)ethoxy]ethoxy}silicon(IV) phthalocyanine

Conditions

Conditions	Yield
With sodium hydride In toluene at 20℃; Inert atmosphere;	18.9%

: 75-21-8
oxirane

: 140-82-9
2-[2-(diethylamino)ethoxy] ethanol

: 3603-40-5
2-[2-(2-diethylamino-ethoxy)-ethoxy]-ethanol

Conditions

Conditions	Yield
at 100℃;

: 859780-32-8
2-ethoxy-quinoline-4-carbonyl chloride

: 140-82-9
2-[2-(diethylamino)ethoxy] ethanol

: 2-ethoxy-quinoline-4-carboxylic acid-[2-(2-diethylamino-ethoxy)-ethyl ester]; hydrochloride

Conditions

Conditions	Yield
With benzene

: 100119-45-7
4-phenyltetrahydropyran-4-carbonyl chloride

: 140-82-9
2-[2-(diethylamino)ethoxy] ethanol

: 13877-98-0
4-phenyl-tetrahydro-pyran-4-carboxylic acid-[2-(2-diethylamino-ethoxy)-ethyl ester]

Conditions

Conditions	Yield
With toluene
With chloroform

: 10249-04-4
2-butoxy-4-quinolinecarbonyl chloride

: 140-82-9
2-[2-(diethylamino)ethoxy] ethanol

: 2-butoxy-quinoline-4-carboxylic acid-[2-(2-diethylamino-ethoxy)-ethyl ester]; hydrochloride

Conditions

Conditions	Yield
With benzene

: 854863-91-5
2-pentyloxy-quinoline-4-carbonyl chloride

: 140-82-9
2-[2-(diethylamino)ethoxy] ethanol

: 2-pentyloxy-quinoline-4-carboxylic acid-[2-(2-diethylamino-ethoxy)-ethyl ester]; hydrochloride

Conditions

Conditions	Yield
With benzene

: 1871-76-7
diphenylacetic acid chloride

: 140-82-9
2-[2-(diethylamino)ethoxy] ethanol

: 102700-71-0
diphenyl-acetic acid-[2-(2-diethylamino-ethoxy)-ethyl ester]

: 2890-42-8
1-phenylcyclohexylcarbonyl chloride

: 140-82-9
2-[2-(diethylamino)ethoxy] ethanol

: 13877-96-8
UCB 597

: 49802-71-3
cyclohexyl-phenyl-acetyl chloride

: 140-82-9
2-[2-(diethylamino)ethoxy] ethanol

: 102702-13-6
cyclohexyl-phenyl-acetic acid-[2-(2-diethylamino-ethoxy)-ethyl ester]

: 17380-62-0
1-phenylcyclopentanecarboxylic acid chloride

: 140-82-9
2-[2-(diethylamino)ethoxy] ethanol

: 77-23-6
carbetapentane

: 140-82-9
2-[2-(diethylamino)ethoxy] ethanol

: 292638-85-8
acrylic acid methyl ester

: 100050-23-5
1-acryloyloxy-2-(2-diethylamino-ethoxy)-ethane

Conditions

Conditions	Yield
With 2,6-di-tert-butyl-4-methyl-phenol; benzene

: 140-82-9
2-[2-(diethylamino)ethoxy] ethanol

: 80-62-6
methacrylic acid methyl ester

: 87553-18-2
1-(2-diethylamino-ethoxy)-2-methacryloyloxy-ethane

Conditions

Conditions	Yield
With N-Phenyl-2-naphthylamine; aluminum isopropoxide

: 140-82-9
2-[2-(diethylamino)ethoxy] ethanol

: 74-86-2
acetylene

: 7307-78-0
N,N-diethyl-2-(2-(vinyloxy)ethoxy)ethanamine

Conditions

Conditions	Yield
With potassium hydroxide; benzene at 160℃;

: 140-82-9
2-[2-(diethylamino)ethoxy] ethanol

: 114456-81-4
2-<2-(diethylamino)ethoxy>ethyl chloride hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride; thionyl chloride; chloroform
With thionyl chloride In benzene for 1.5h; Heating;

: 94231-78-4
1-azaphenothiazine-10-carbonyl chloride

: 140-82-9
2-[2-(diethylamino)ethoxy] ethanol

: benzo[b]pyrido[2,3-e][1,4]thiazine-10-carboxylic acid 2-(2-diethylamino-ethoxy)-ethyl ester

Conditions

Conditions	Yield
In chlorobenzene Heating;

: 39889-69-5
biphenyl-4-yl-acetyl chloride

: 140-82-9
2-[2-(diethylamino)ethoxy] ethanol

: 95160-43-3
<4>Biphenylylessigsaeure-<2-(2-diaethylamino-aethoxy)-aethylester>

Conditions

Conditions	Yield
With pyridine In chloroform Heating;

: 75-04-7
ethylamine

: 140-82-9
2-[2-(diethylamino)ethoxy] ethanol

: 116054-92-3
(2-ethylamino-ethyl)-(2-diethylamino-ethyl)-ether

Conditions

Conditions	Yield
(i) SOBr2, benzene, (ii) /BRN= 505933/, EtOH; Multistep reaction;

: Propyl-propargylessigsaeurechlorid

: 140-82-9
2-[2-(diethylamino)ethoxy] ethanol

: 35812-12-5
Propylpropargylacetat-2-(2'-diethylaminoethoxi)ethylester

Conditions

Conditions	Yield
With potassium carbonate In toluene at 100℃;

: 41641-76-3
2-biphenyl-4-yl-butyryl chloride

: 140-82-9
2-[2-(diethylamino)ethoxy] ethanol

: 96586-27-5
α-Aethyl-<4>biphenylylessigsaeure-<2-(2-diaethylamino-aethoxy)-aethylester>

Conditions

Conditions	Yield
With pyridine In chloroform Heating;

: 2287-32-3
1-[2-(2-chloroethoxy)ethoxy]-2-methoxybenzene

: 140-82-9
2-[2-(diethylamino)ethoxy] ethanol

: 2293-39-2
1-Diaethylamino-11-(2-methoxy-phenoxy)-3,6,9-trioxa-undecan

Conditions

Conditions	Yield
(i) Na, xylene, (ii) /BRN= 2110861/; Multistep reaction;

: 2287-33-4
5-methyl-2-isopropylphenoxyethoxyethyl chloride

: 140-82-9
2-[2-(diethylamino)ethoxy] ethanol

: 859-20-1
1-Diethylamino-11-<6-isopropyl-3-methyl-phenoxy>-3,6,9-trioxa-undecan

Conditions

Conditions	Yield
(i) Na, xylene, (ii) /BRN= 2267168/; Multistep reaction;

: 22004-65-5
α-(2,6-dimethylphenyl)-2,6-dimethylbenzenemethanol

: 140-82-9
2-[2-(diethylamino)ethoxy] ethanol

: 2212-34-2
(2-{2-[Bis-(2,6-dimethyl-phenyl)-methoxy]-ethoxy}-ethyl)-diethyl-amine

Conditions

Conditions	Yield
(i) HCl, benzene, (ii) /BRN= 506197/; Multistep reaction;

6-Ethyl-3-oxa-6-azaoctanol Chemical Properties

Chemical Name: 6-Ethyl-3-oxa-6-azaoctanol
IUPAC NAME: 2-(2-diethylaminoethyloxy)ethanol
CAS No.: 140-82-9
EINECS: 205-436-7
Molecular Formula: C₈H₁₉NO₂
Molecular Weight: 161.24 g/mol
Density: 0.939 g/cm³
Melting Point: 101°C
Flash Point: 95.8 °C
Boiling Point: 234.7 °C at 760 mmHg
Following is the structure of 2-(2-(DIETHYLAMINO)ETHOXY)ETHANOL(140-82-9):

The chemical synonymous of 2-(2-(DIETHYLAMINO)ETHOXY)ETHANOL(140-82-9) are 2-(2-(diethylamino)ethoxy)-ethano;2-(beta-(diethylamino)ethoxy)ethanol;2-[2-(diethylamino)ethoxy]-ethano;2-beta-Diethylaminoethoxyethanol;beta-(Diethylamino ethoxy)ethanol;Diethylaminoethoxyethanol;diethylaminoethoxyethanol,[combustibleliquidlabel];diethylaminoethoxyethanol,[flammableliquidlabel].

6-Ethyl-3-oxa-6-azaoctanol Uses

2-(2-(DIETHYLAMINO)ETHOXY)ETHANOL(140-82-9) is mainly used for the production of antitussives carbetapentane.

6-Ethyl-3-oxa-6-azaoctanol Production

Product Categories about 2-(2-(DIETHYLAMINO)ETHOXY)ETHANOL(140-82-9) are Alkohols;Ethylene Glycols & Monofunctional Ethylene Glycols;Monofunctional Ethylene Glycols.

6-Ethyl-3-oxa-6-azaoctanol Toxicity Data With Reference

1.	skn-rbt 10 µL MLD open	NTIS** National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) OTS0535166 .
2.	eye-rbt 5 µL/24H SEV	NTIS** National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) OTS0535166 .

rabbit	LD50	skin	2020uL/kg (2.02mL/kg)	GASTROINTESTINAL: OTHER CHANGES LIVER: OTHER CHANGES SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"	National Technical Information Service. Vol. OTS0535166,
rat	LD50	oral	2590uL/kg (2.59mL/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: OTHER CHANGES	National Technical Information Service. Vol. OTS0535166,

6-Ethyl-3-oxa-6-azaoctanol Safety Profile

A poison by ingestion and skin contact. A severe eye and mild skin irritant. When heated to decomposition it emits toxic vapors of NO_x.
Safety Statements about 2-(2-(DIETHYLAMINO)ETHOXY)ETHANOL(140-82-9):
S23 Do not breathe vapour.
S24/25: Avoid contact with skin and eyes.
Health Hazard: Inhalation or contact with material may irritate or burn skin and eyes. Fire may produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control may cause pollution.
Fire Hazard: HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

6-Ethyl-3-oxa-6-azaoctanol Specification

Reactivity Profile: 6-Ethyl-3-oxa-6-azaoctanol is an amine and alcohol. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

Product Name

6-Ethyl-3-oxa-6-azaoctanol

Synthetic route

6-Ethyl-3-oxa-6-azaoctanol Chemical Properties

6-Ethyl-3-oxa-6-azaoctanol Uses

6-Ethyl-3-oxa-6-azaoctanol Production

6-Ethyl-3-oxa-6-azaoctanol Toxicity Data With Reference

6-Ethyl-3-oxa-6-azaoctanol Safety Profile

6-Ethyl-3-oxa-6-azaoctanol Specification

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