8-Aminoquinaldine

The 8-Quinolinamine,2-methyl-, with the CAS registry number 18978-78-4, is also known as 2-Methyl-8-aminoquinoline. It belongs to the product categories of Amines; Alkylquinolines; Aminoquinolines; Quinolines. This chemical's molecular formula is C₁₀H₁₀N₂ and molecular weight is 158.20. What's more, its systematic name is 2-methylquinolin-8-amine. 

Physical properties of 8-Quinolinamine,2-methyl- are: (1)ACD/LogP: 2.34; (2)# of Rule of 5 Violations: 0; (3)#H bond acceptors: 2; (4)#H bond donors: 2; (5)#Freely Rotating Bonds: 1; (6)Polar Surface Area: 16.13 Å²; (7)Index of Refraction: 1.681; (8)Molar Refractivity: 51.24 cm³; (9)Molar Volume: 135.3 cm³; (10)Polarizability: 20.31×10^-24cm³; (11)Surface Tension: 55.1 dyne/cm; (12)Density: 1.169 g/cm³; (13)Flash Point: 171.1 °C; (14)Enthalpy of Vaporization: 55.8 kJ/mol; (15)Boiling Point: 316.6 °C at 760 mmHg; (16)Vapour Pressure: 0.000405 mmHg at 25°C.

Preparation of 8-Quinolinamine,2-methyl-: this chemical can be prepared by 2-methyl-8-nitro-quinoline by heating. This reaction will need reagent N₂H₄·H₂O and solvent methanol with the reaction time of 3 hours. This reaction will also need catalyst 10% Pd/C. The yield is about 95%.

Uses of 8-Quinolinamine,2-methyl-: it can be used to produce N-(2-methyl-quinolin-8-yl)-methanesulfonamide at the temperature of 60 °C. It will need reagents pyridine, H₂O and solvent benzene with the reaction time of 30 min. The yield is about 55%.

When you are using this chemical, please be cautious about it as the following:
It is harmful by inhalation, in contact with skin and if swallowed. You should not breathe dust. When using it, you need wear suitable protective clothing, gloves and eye/face protection.

You can still convert the following datas into molecular structure:
(1)SMILES: n1c(ccc2cccc(N)c12)C
(2)Std. InChI: InChI=1S/C10H10N2/c1-7-5-6-8-3-2-4-9(11)10(8)12-7/h2-6H,11H2,1H3
(3)Std. InChIKey: JHIAOWGCGNMQKA-UHFFFAOYSA-N