-
Name
ACETAZOLAMIDE SODIUM
- EINECS
- CAS No. 1424-27-7
- Density
- Solubility
- Melting Point 258-259oC (EFFERVESCENCE)
- Formula C4H6 N4 O3 S2 . Na
- Boiling Point
- Molecular Weight 244.24
- Flash Point
- Transport Information
- Appearance
- Safety An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits very toxic fumes of NOx, Na2O, and SOx.
- Risk Codes
-
Molecular Structure
- Hazard Symbols
- Synonyms 1,3,4-Thiadiazole-2-sulfonamide,5-acetamido-, sodium deriv. (6CI,7CI); Acetamide,N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)-, monosodium salt (8CI); Acetamide,N-[5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl]-, monosodium salt (9CI);Acetazolamide sodium; Acetazolamide sodium salt; Diamox Parenteral; Sodiumacetazolamidate; Sodium acetazolamide; Vetamox
- PSA 142.87000
- LogP 0.78380
Acetazolamide sodium Chemical Properties
Molecular Structure of Acetazolamide sodium (CAS NO.1424-27-7):
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IUPAC Name: sodium (5-acetamido-1,3,4-thiadiazol-2-yl)sulfonylazanide
Empirical Formula: C4H5N4NaO3S2
Molecular Weight: 244.2273
Synonyms of Acetazolamide sodium (CAS NO.1424-27-7): Acetazolamide sodium ; acetazolamidesodiumsalt ; diamoxsodium ; n-(5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl)-acetamidmonosodiumsalt ; n-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)-acetamidmonosodiumsalt ; sodiumacetazolamide
Acetazolamide sodium Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| dog | LD | intravenous | > 2gm/kg (2000mg/kg) | Bulletin of the Johns Hopkins Hospital. Vol. 95, Pg. 199, 1954. | |
| guinea pig | LDLo | subcutaneous | 1500mg/kg (1500mg/kg) | Bulletin of the Johns Hopkins Hospital. Vol. 95, Pg. 199, 1954. | |
| mouse | LD50 | intravenous | 3gm/kg (3000mg/kg) | Bulletin of the Johns Hopkins Hospital. Vol. 95, Pg. 199, 1954. | |
| rat | LD | oral | > 1gm/kg (1000mg/kg) | Bulletin of the Johns Hopkins Hospital. Vol. 95, Pg. 199, 1954. | |
| rat | LDLo | subcutaneous | 3gm/kg (3000mg/kg) | Bulletin of the Johns Hopkins Hospital. Vol. 95, Pg. 199, 1954. |
Acetazolamide sodium Safety Profile
An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits very toxic fumes of NOx, Na2O, and SOx.
Acetazolamide sodium Specification
Acetazolamide sodium (CAS NO.1424-27-7) is a high-toxic material, flammable,thermal decomposition would release highly toxic nitrogen oxides, sulfur oxides and sodium oxide fumes,it should be stored in low temperature, ventilation, drying environmental conditions,separated with food and raw materials, besides water, carbon oxides and oxidation of toxic carbon dioxide, dry powder, sand, water mist fire extinguishing agent can be used if emergency.
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