Agmatine supplier | CasNO.306-60-5

Name
AGMATINE SULFATE ENDOGENOUS AGONIST AT
EINECS 206-187-7
CAS No. 306-60-5
Article Data24
CAS DataBase
Density 1.2 g/cm³
Solubility
Melting Point
Formula C₅H₁₄N₄
Boiling Point 281.4 °C at 760 mmHg
Molecular Weight 130.193
Flash Point 124 °C
Transport Information
Appearance powder
Safety
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms Agmatine(6CI);Guanidine, (4-aminobutyl)- (8CI,9CI);(4-Aminobutyl)guanidine;1,4-Butanediamine, N-(aminoiminomethyl)-;1-Amino-4-guanidinobutane;4-Guanidino-1-butanamine;N-(4-Aminobutyl)guanidine;NSC 56332;2-(4-aminobutyl)guanidine;1-(4-Aminobutyl)guanidin;1-Amino-4-guanidinobutane;2-(4-aminobutyl)guanidine;Guanidine, (4-aminobutyl)-;agmatine;
PSA 87.92000
LogP 1.09960

Synthetic route

: 2986-21-2
S-n-propylisothiourea

: 110-60-1
1,4-diaminobutane

: 306-60-5
1-(4-aminobutyl)guanidine

Conditions

Conditions	Yield
at 80℃; for 0.75h;	96%

: 23441-10-3
N-Benzyloxycarbonyl-NG-nitroagmatin

: 306-60-5
1-(4-aminobutyl)guanidine

Conditions

Conditions	Yield
With formic acid; palladium on activated charcoal In methanol for 2h; Ambient temperature;	52%
With formic acid; palladium on activated charcoal In methanol at 25℃; for 2h; Yield given;

: 74-79-3
L-arginine

: 306-60-5
1-(4-aminobutyl)guanidine

Conditions

Conditions	Yield
durch Escherichia coli;
With Escherichia coli
With E.coli; streptococcus faecalis bei pH 4;
With L-arginine decarboxylase; pyridoxal 5'-phosphate; diothiothreitol In phosphate buffer at 50℃; for 0.166667h; pH=6.5;
With 3,5,5-Trimethylcyclohex-2-en-1-one In isopropyl alcohol at 150℃; for 4h; Autoclave;

: 420-04-2
CYANAMID

: 110-60-1
1,4-diaminobutane

: 306-60-5
1-(4-aminobutyl)guanidine

Conditions

Conditions	Yield
With water
With barium sulfate

: 14527-26-5, 867-44-7
2-methylisothiourea sulphate

: 110-60-1
1,4-diaminobutane

: 306-60-5
1-(4-aminobutyl)guanidine

: 22906-75-8
3,5-Dimethylpyrazole-1-carboxamidine

: 18807-73-3
N-benzyloxycarbonyl-1,4-butanediamine hydrochloride

: 306-60-5
1-(4-aminobutyl)guanidine

Conditions

Conditions	Yield
(i) aq. NaOH, EtOH, (ii) aq. HBr; Multistep reaction;

arcain: arcain

: 306-60-5
1-(4-aminobutyl)guanidine

Conditions

Conditions	Yield
With saprophytes
With barium dihydroxide; water

herring-milt: herring-milt

: 306-60-5
1-(4-aminobutyl)guanidine

Conditions

Conditions	Yield
With sulfuric acid Hydrolysis;

cyanamide silver: cyanamide silver

hydrochloride of tetramethylenediamine: hydrochloride of tetramethylenediamine

: 306-60-5
1-(4-aminobutyl)guanidine

Conditions

Conditions	Yield
With carbon dioxide; water

: 110-60-1
1,4-diaminobutane

S-methyl-thiuronium-sulfate: S-methyl-thiuronium-sulfate

: 306-60-5
1-(4-aminobutyl)guanidine

Conditions

Conditions	Yield
With water

: 2482-00-0
agmatine sulphate

: 306-60-5
1-(4-aminobutyl)guanidine

Conditions

Conditions	Yield
With tetramethyl ammoniumhydroxide In methanol for 1h;

S-methylthiopseudourea.H2 SO4: S-methylthiopseudourea.H2 SO4

: 110-60-1
1,4-diaminobutane

: 306-60-5
1-(4-aminobutyl)guanidine

Conditions

Conditions	Yield
In water

: 306-60-5
1-(4-aminobutyl)guanidine

: (4R*,5R*)-5-diisopropyloxyphosphoryl-5-methyl-4-(succinimidyloxycarbonyloxymethyl)-1-pyrroline N-oxide

: 5-(diisopropyloxyphosphoryl)-5-methyl-4-[({[2-(guanidino)buthyl]carbamoyl}oxy)methyl]-5-methyl-1-pyrroline N-oxide

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine In acetonitrile	95%

: 306-60-5
1-(4-aminobutyl)guanidine

: 4055-39-4
mitomycin A

: 103095-05-2
C20H29N7O5

Conditions

Conditions	Yield
In methanol	70%

: 87-51-4
indole-3-acetic acid

: 306-60-5
1-(4-aminobutyl)guanidine

: 66-99-9
β-naphthaldehyde

: 76-05-1
trifluoroacetic acid

: 949592-43-2
N-(4-guanidinobutyl)-2-(1H-indol-3-yl)-N-((naphthalen-2-yl)methyl)acetamide trifluoroacetic acid salt

Conditions

Conditions	Yield
Multistep reaction.;	26%

...Expand

: 133-32-4
4-indol-3-yl-butyric acid

: 306-60-5
1-(4-aminobutyl)guanidine

: 66-99-9
β-naphthaldehyde

: 76-05-1
trifluoroacetic acid

: 949592-47-6
N-(4-guanidinobutyl)-4-(1H-indol-3-yl)-N-((naphthalen-2-yl)methyl)butanamide trifluoroacetic acid salt

Conditions

Conditions	Yield
Multistep reaction.;	24%

...Expand

: 306-60-5
1-(4-aminobutyl)guanidine

: 65178-90-7
2-[4-(4-chlorobenzoyl)-phenoxy]-2-methylpropionyl chloride

: 1094098-88-0
2-(4-(4-chlorobenzoyl)phenoxy)-N-(4-guanidinobutyl)-2-methylpropanamide

Conditions

Conditions	Yield
With pyridine	10%

: 306-60-5
1-(4-aminobutyl)guanidine

: 119-53-9
2-hydroxy-2-phenylacetophenone

: N1-(4,5-Diphenyl-1H-imidazol-2-yl)-butane-1,4-diamine

Conditions

Conditions	Yield
With potassium hydroxide; 2-hydroxyethanethiol; sodium sulfite In water at 100℃; for 0.166667h;

: 306-60-5
1-(4-aminobutyl)guanidine

: 14049-14-0
γ-guanidino butyraldehyde

Conditions

Conditions	Yield
With potassium phosphate buffer (pH: 7.0) at 35℃; for 0.333333h; agmatine oxidase from Penicillium chrysogenum;

: 306-60-5
1-(4-aminobutyl)guanidine

calcium permanganate: calcium permanganate

A: 110-15-6
succinic acid

B: 463-00-3
4-guanidinobutyric acid

C: 113-00-8
guanidine nitrate

Conditions

Conditions	Yield
bei der Oxydation;

...Expand

: 306-60-5
1-(4-aminobutyl)guanidine

: 16331-45-6
p-ethylbenzoyl chloride

: 94-09-7
p-aminoethylbenzoate

: C21H27N5O2

Conditions

Conditions	Yield
Multistep reaction;

...Expand

: 23911-26-4
diethylenetriaminepentaacetic dianhydride

: 306-60-5
1-(4-aminobutyl)guanidine

: 616205-57-3
diethylenetriamine-N,N''-bis(4-guanidinobutyl)-N,N',N''-triacetic acid

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 50℃; for 4h;
In dimethyl sulfoxide at 50℃; for 10h;
In dimethyl sulfoxide at 20 - 50℃; for 24h;

: C24H24FN3O6

: 306-60-5
1-(4-aminobutyl)guanidine

: C29H38FN7O5

Conditions

Conditions	Yield
With sodium tris(acetoxy)borohydride; acetic acid In methanol; dichloromethane at 25℃; for 12h;

: 306-60-5
1-(4-aminobutyl)guanidine

: 7144-08-3
Cholesteryl chloroformate

: agmatinyl carboxycholesterol acetic acid salt

Conditions

Conditions	Yield
Stage #1: 1-(4-aminobutyl)guanidine; Cholesteryl chloroformate In DMF (N,N-dimethyl-formamide) at 20℃; for 72h; Stage #2: With acetic acid

poly(NHS-acrylate): poly(NHS-acrylate)

: 306-60-5
1-(4-aminobutyl)guanidine

: Poly(guanidinobutylacrylamide)

Conditions

Conditions	Yield
In water; isopropyl alcohol
In water; isopropyl alcohol

: 306-60-5
1-(4-aminobutyl)guanidine

: 52355-54-1
2-(n-octyl)cyclopropanecarbonyl chloride

: 117414-73-0
1-(2-n-octylcyclopropanecarboxamido)-4-guanidinobutane

Conditions

Conditions	Yield
In pyridine; methanol; chloroform

Agmatine Specification

The Guanidine,N-(4-aminobutyl)-, with the CAS registry number 306-60-5 and EINECS registry number 206-187-7, has the systematic name and IUPAC name of 2-(4-aminobutyl)guanidine. And the molecular formula of the chemical is C₅H₁₄N₄.

The characteristics of Guanidine,N-(4-aminobutyl)- are as followings: (1)ACD/LogP: -1.04; (2)# of Rule of 5 Violations: 1; (3)ACD/LogD (pH 5.5): -5.14; (4)ACD/LogD (pH 7.4): -5.13; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1; (8)ACD/KOC (pH 7.4): 1; (9)#H bond acceptors: 4; (10)#H bond donors: 6; (11)#Freely Rotating Bonds: 5; (12)Polar Surface Area: 22.08 Å²; (13)Index of Refraction: 1.55; (14)Molar Refractivity: 34.38 cm³; (15)Molar Volume: 107.8 cm³; (16)Polarizability: 13.63×10^-24cm³; (17)Surface Tension: 51.3 dyne/cm; (18)Density: 1.2 g/cm³; (19)Flash Point: 124 °C; (20)Enthalpy of Vaporization: 52.02 kJ/mol; (21)Boiling Point: 281.4 °C at 760 mmHg; (22)Vapour Pressure: 0.00357 mmHg at 25°C.

Uses of Guanidine,N-(4-aminobutyl)-: It can react with mitomycin A to produce C₂₀H₂₉N₇O₅. This reaction will need menstruum methanol. And the yield is about 92%.

Addtionally, the following datas could be converted into the molecular structure:
(1)SMILES: N(=C(\N)N)\CCCCN
(2)InChI: InChI=1/C5H14N4/c6-3-1-2-4-9-5(7)8/h1-4,6H2,(H4,7,8,9)
(3)InChIKey: QYPPJABKJHAVHS-UHFFFAOYAX

Product Name

AGMATINE SULFATE ENDOGENOUS AGONIST AT

Synthetic route

Agmatine Specification

Related Products

Hot Products