Product Name

  • Name

    Amifostine hydrate

  • EINECS
  • CAS No. 63717-27-1
  • Density
  • Solubility
  • Melting Point 160-161° (dec)
  • Formula C5H15N2O3PS.H2O
  • Boiling Point 441.7oC at 760 mmHg
  • Molecular Weight 232.23800
  • Flash Point 220.9oC
  • Transport Information
  • Appearance
  • Safety
  • Risk Codes
  • Molecular Structure Molecular Structure of 63717-27-1 (Amifostine hydrate)
  • Hazard Symbols
  • Synonyms Amifostine hydrate;Amifostinum;Amifostina;amifostine monohydrate;
  • PSA 139.92000
  • LogP 0.77760

Amifostine hydrate Chemical Properties

IUPAC Name: 2-(3-Aminopropylamino)ethylsulfanylphosphonic acid hydrate
The molecular formula of Amifostine hydrate (CAS NO.63717-27-1) is C5H17N2O4PS.

                            
The molecular weight of Amifostine hydrate (CAS NO.63717-27-1) is 232.24.
Synonyms of Amifostine hydrate (CAS NO.63717-27-1): Ethanethiol, 2-((3-aminopropyl)amino)-, dihydrogen phosphate (ester) hydrate ; Phosphorothioic acid, S-(2-((3-aminopropyl)amino)ethyl) ester, hydrate
Enthalpy of Vaporization: 76.64 kJ/mol
Flash Point: 220.9 °C   
Boiling Point: 441.7 °C

Amifostine hydrate Uses

 Amifostine hydrate (CAS NO.63717-27-1) is used as pharmaceutical intermediate.

Amifostine hydrate Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 700mg/kg (700mg/kg)   Journal of Medicinal Chemistry. Vol. 12, Pg. 236, 1969.
mouse LD50 unreported 375mg/kg (375mg/kg)   Journal of Medicinal Chemistry. Vol. 9, Pg. 911, 1966.

Amifostine hydrate Safety Profile

Poison by unspecified route. Moderately toxic by intraperitoneal route. When heated to decomposition it emits very toxic fumes of NOx, POx, and SOx. See also ESTERS.

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