Product Name

  • Name

    Antazoline

  • EINECS 202-094-0
  • CAS No. 91-75-8
  • Article Data8
  • CAS DataBase
  • Density 1.1 g/cm3
  • Solubility 663.4mg/L(30 oC)
  • Melting Point 159oC
  • Formula C17H19N3
  • Boiling Point 475.5 °C at 760 mmHg
  • Molecular Weight 265.358
  • Flash Point 241.4 °C
  • Transport Information
  • Appearance Crystals. Odorless.
  • Safety
  • Risk Codes
  • Molecular Structure Molecular Structure of 91-75-8 (Antazoline)
  • Hazard Symbols
  • Synonyms 2-Imidazoline,2-[(N-benzylanilino)methyl]- (8CI);2-[(N-Benzylanilino)methyl]-2-imidazoline;Allergan A;Antistine;Phenazoline;
  • PSA 27.63000
  • LogP 2.45930

Antazoline Chemical Properties

Phenazoline is also named as Antazoline;1H-Imidazole-2-methanamine, 4,5-dihydro-N-phenyl-N-(phenylmethyl)-;2-(N-Phenyl-N-benzylaminomethyl)imidazoline;2-[(N-Benzylanilino)methyl]-2-imidazol;2-[(N-Benzylanilino)methyl]-2-imidazoline;2-Imidazoline, 2-[(N-benzylanilino)methyl]-;2-Phenyl-benzyl-amino-methylimidazolin;4,5-Dihydro-N-phenyl-N-phenylmethyl-1H-imidazole-2-methanamine,and so on.

Molecular Formula: C17H19N3
Molecular Weight: 265.35
EINECS: 202-094-0
Appearance:Crystals. Odorless.
Solubility in water:Insoluble
Melting Point:159 °C
Boiling Point:210 - 220 °C (0.7 torr)
Density:1.188 g/cm3

Antazoline Uses

Phenazoline is the 1st generation antihistamine used to relieve nasal congestion and in eye drops,and it can be used to relieve the symptoms of allergic.

Antazoline Toxicity Data With Reference

1.   

eye-rbt 1%

   OPHTAD    Ophtalmologica. 143 (1962),154.
2.   

orl-mus LD50:398 mg/kg

   ARZNAD    Arzneimittel-Forschung. Drug Research. 7 (1957),237.
3.   

ipr-mus LD50:100 mg/kg

   AEPPAE    Naunyn-Schmiedeberg’s Archiv fuer Experimentelle Pathologie und Pharmakologie. 237 (1959),171.
4.   

scu-mus LD50:135 mg/kg

   ARZNAD    Arzneimittel-Forschung. Drug Research. 17 (1967),214.

RTECS:  NJ2000000

Antazoline Safety Profile

Poison by ingestion, subcutaneous, and intraperitoneal routes. An eye irritant. When heated to decomposition it emits toxic fumes of NOx.

Hazardous Substances Data: 91-75-8(Hazardous Substances Data)

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