Product Name

  • Name

    Azapropazone

  • EINECS
  • CAS No. 22304-30-9
  • Density 1.29g/cm3
  • Solubility
  • Melting Point 247-248°
  • Formula C16H20 N4 O2 . 2 H2 O
  • Boiling Point 438°Cat760mmHg
  • Molecular Weight 336.44
  • Flash Point 218.7°C
  • Transport Information
  • Appearance
  • Safety Moderately toxic by ingestion, intraperitoneal, subcutaneous and intravenous routes. An eye irritant. When heated to decomposition it emits toxic fumes of NOx. An anti-inflammatory and analgesic agent.
  • Risk Codes
  • Molecular Structure Molecular Structure of 22304-30-9 (Azapropazone)
  • Hazard Symbols
  • Synonyms 1H-Pyrazolo[1,2-a][1,2,4]benzotriazine-1,3(2H)-dione,5-(dimethylamino)-9-methyl-2-propyl-, dihydrate (8CI,9CI)
  • PSA 60.13000
  • LogP 2.48470

Apazone dihydrate Chemical Properties

Molecular Formula of Apazone dihydrate (CAS NO.22304-30-9): C16H24N4O4
Molecular Weight: 336.38616 g/mol
Flashing point: 218.7 °C
Index of Refraction: 1.646
Density: 1.29 g/cm3
Vapour Pressure: 7.16E-08 mmHg at 25 °C
Boiling Point: 438 °C at 760 mmHg
Structure of Apazone dihydrate (CAS NO.22304-30-9):
                       
IUPAC Name: 5-(Dimethylamino)-9-methyl-2-propylpyrazolo[1,2-a][1,2,4]benzotriazine-1,3-dione dihydrate
Canonical SMILES: CCCC1C(=O)N2C3=C(C=CC(=C3)C)N=C(N2C1=O)N(C)C.O.O
InChI: InChI=1S/C16H20N4O2.2H2O/c1-5-6-11-14(21)19-13-9-10(2)7-8-12(13)17-16(18(3)4)20(19)15(11)22;;/h7-9,11H,5-6H2,1-4H3;2*1H2
InChIKey: LLMGYOJUHDRDFJ-UHFFFAOYSA-N

Apazone dihydrate Toxicity Data With Reference

1.    

eye-rbt 100 mg MLD

     CMROCX    Current Medical Research and Opinion. 4 (1976),17.
2.    

orl-rat LD50:1950 mg/kg

     ARZNAD    Arzneimittel-Forschung. Drug Research. 23 (1973),1215.
3.    

ipr-rat LD50:1101 mg/kg

     TOIZAG    Toho Igakkai Zasshi. Journal of Medical Society of Toho University. 19 (1972),242.
4.    

scu-rat LD50:1101 mg/kg

     TOIZAG    Toho Igakkai Zasshi. Journal of Medical Society of Toho University. 19 (1972),242.
5.    

ivn-rat LD50:710 mg/kg

     ARZNAD    Arzneimittel-Forschung. Drug Research. 19 (1969),36.
6.    

orl-mus LD50:1080 mg/kg

     ARZNAD    Arzneimittel-Forschung. Drug Research. 23 (1973),1215.
7.    

ipr-mus LD50:1107 mg/kg

     TOIZAG    Toho Igakkai Zasshi. Journal of Medical Society of Toho University. 19 (1972),242.
8.    

scu-mus LD50:1190 mg/kg

     TOIZAG    Toho Igakkai Zasshi. Journal of Medical Society of Toho University. 19 (1972),242.
9.    

ivn-mus LD50:750 mg/kg

     ARZNAD    Arzneimittel-Forschung. Drug Research. 19 (1969),36.

Apazone dihydrate Safety Profile

Moderately toxic by ingestion, intraperitoneal, subcutaneous and intravenous routes. An eye irritant. When heated to decomposition Apazone dihydrate (CAS NO.22304-30-9) emits toxic fumes of NOx. An anti-inflammatory and analgesic agent.

Apazone dihydrate Specification

 Apazone dihydrate , its cas register number is 22304-30-9. It also can be called Prolixana ; Tolyprin ; Rheumox ; 1,2-Dihydro-3-dimethylamino-7-methyl-1,2-(propylmalonyl)-1,2,4-benzotriazine dihydrate ; and Prolixan .

Related Products

Hot Products

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View