IUPAC Name: 2-[[(1R,3S)-3-[bis(2-chloroethyl)amino]-3-oxo-4-oxa-2-aza-3λ5-phosphacyclohex-1-yl]sulfanyl]ethanesulfonic acid ; cyclohexanamine
Molecular Weight: 500.441441 g/mol
Molecular Formula: C15H32Cl2N3O5PS2
H-Bond Donor: 3
H-Bond Acceptor: 8
Rotatable Bond Count: 9
Tautomer Count: 2
MonoIsotopic Mass: 499.089804
Topological Polar Surface Area: 122
Heavy Atom Count: 28
Complexity: 502
Defined Atom StereoCenter Count: 2
Isomeric SMILES: C1CCC(CC1)N.C1CO[P@@](=O)(N[C@@H]1SCCS(=O)(=O)O)N(CCCl)CCCl
InChI: InChI=1S/C9H19Cl2N2O5PS2.C6H13N/c10-2-4-13(5-3-11)19(14)12-9(1-6-18-19)20-7-8-21(15,16)17;7-6-4-2-1-3-5-6/h9H,1-8H2,(H,12,14)(H,15,16,17);6H,1-5,7H2/t9-,19+;/m1./s1
InChIKey: AJOJXYODECALSX-BCPQDLGFSA-N
Synonyms of Asta z 7557 (CAS NO.88746-71-8) : Mafosfamide cyclohexylamine salt ; 2-[[2-[bis(2-chloroethyl)amino]-1,3,2-oxazaphosphinan-4-yl]sulfanyl]et hanesulfonic acid |: cyclohexanamine ; 2-[[2-[Bis(2-chloroethyl)amino]-1,3,2-oxazaphosphinan-4-yl]sulfanyl]ethanesulfonic acid ; 2-[Bis(2-chloroethyl)amino]-4-[(2-sulfoethyl)thio]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide
1. | dnd-hmn:lym 50 mg/L | INNDDK Investigational New Drugs. The Journal of New Anticancer Agents. 2 (1984),161. | ||
2. | dnd-mus-ipr 250 µmol/kg | INNDDK Investigational New Drugs. The Journal of New Anticancer Agents. 2 (1984),181. | ||
3. | dnd-mus:lym 12,500 µg/kg | INNDDK Investigational New Drugs. The Journal of New Anticancer Agents. 2 (1984),161. | ||
4. | orl-rat LD50:1 g/kg | INNDDK Investigational New Drugs. The Journal of New Anticancer Agents. 2 (1984),201. | ||
5. | ivn-rat LD50:250 mg/kg | INNDDK Investigational New Drugs. The Journal of New Anticancer Agents. 2 (1984),201. | ||
6. | orl-mus LD50:2310 mg/kg | INNDDK Investigational New Drugs. The Journal of New Anticancer Agents. 2 (1984),201. | ||
7. | ipr-mus LD50:315 mg/kg | INNDDK Investigational New Drugs. The Journal of New Anticancer Agents. 2 (1984),253. | ||
8. | ivn-mus LD50:500 mg/kg | INNDDK Investigational New Drugs. The Journal of New Anticancer Agents. 2 (1984),201. |
Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. Human mutation data reported. When heated to decomposition it emits toxic fumes of Cl−, POx, SOx, and NOx. See also ESTERS and SULFONATES.
Asta z 7557 (CAS NO.88746-71-8) is moderate toxic.The storage environment should be ventilate, low-temperature and dry. Asta z 7557 (CAS NO.88746-71-8) can produce nitrogen oxides, sulfur oxides, phosphorous oxides and chloride fumes when buring.
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View