Azaprocin supplier | CasNO.448-34-0

Name
Azaprocin
EINECS
CAS No. 448-34-0
Density 1.096g/cm³
Solubility
Melting Point
Formula C18H24 N2 O
Boiling Point 462.5°Cat760mmHg
Molecular Weight 284.401
Flash Point 202.8°C
Transport Information
Appearance
Safety
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms 3,8-Diazabicyclo[3.2.1]octane,3-cinnamyl-8-propionyl- (7CI,8CI);3,8-Diazabicyclo[3.2.1]octane,8-(1-oxopropyl)-3-(3-phenyl-2-propenyl)- (9CI);3-Cinnamyl-8-propionyldiazabicyclo[3.2.1]octane;Azaprocin;
PSA 23.55000
LogP 2.66080

Azaprocin Specification

The Azaprocin, with the CAS registry number 448-34-0, is also known as 3-Cinnamyl-8-propionyldiazabicyclo[3.2.1]octane.It belongs to the product organic matter.This chemical's molecular formula is C₁₈H₂₄N₂O and molecular weight is 284.39. What's more, Its systematic name is 1-[(1S,5R)-3-cinnamyl-3,8-diazabicyclo[3.2.1]octan-8-yl]propan-1-one. Azaprocin is a drug which is an opioid analgesic with approximately 10x the potency of morphine, and a fast onset and short duration of action.

Physical properties about Azaprocin are: (1)ACD/LogP: 2.793; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.18; (4)ACD/LogD (pH 7.4): 2.61 ; (5)ACD/BCF (pH 5.5): 1.91; (6)ACD/BCF (pH 7.4): 51.47; (7)ACD/KOC (pH 5.5): 19.30; (8)ACD/KOC (pH 7.4): 519.09; (9)#H bond acceptors: 3; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 4; (12)Index of Refraction: 1.584; (13)Molar Refractivity: 86.848 cm³; (14)Molar Volume: 259.265 cm³; (15)Surface Tension: 43.7630004882813 dyne/cm; (16)Density: 1.097 g/cm³; (17)Flash Point: 202.8 °C; (18)Enthalpy of Vaporization: 72.358 kJ/mol; (19)Boiling Point: 462.519 °C at 760 mmHg; (20)Vapour Pressure: 0 mmHg at 25°C;

You can still convert the following datas into molecular structure:
(1)SMILES:CCC(=O)N3[C@@H]2CC[C@H]3CN(C/C=C/c1ccccc1)C2;
(2)Std. InChI:InChI=1S/C18H24N2O/c1-2-18(21)20-16-10-11-17(20)14-19(13-16)12-6-9-15-7-4-3-5-8-15/h3-9,16-17H,2,10-14H2,1H3/b9-6+/t16-,17+;
(3)Std. InChIKey:RKNSPEOBXHFNTD-DQCUJPBYSA-N;

The toxicity data of Azaprocin as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	73mg/kg (73mg/kg)		Research Progress in Organic-Biological and Medicinal Chemistry. Vol. 2, Pg. 196, 1970.
mouse	LD50	intravenous	33mg/kg (33mg/kg)		Research Progress in Organic-Biological and Medicinal Chemistry. Vol. 2, Pg. 203, 1970.

Product Name

Azaprocin

Azaprocin Specification

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