• Name

  Bis[3-(triethoxysilyl)propyl]amine

• EINECS 236-818-1
• CAS No. 13497-18-2
• Article Data11
• CAS DataBase
• Density 0.958 g/cm³
• Solubility 23-1000000mg/L at 20℃
• Melting Point <0 °C
• Formula C₁₈H₄₃NO₆Si₂
• Boiling Point 408 °C at 760 mmHg
• Molecular Weight 425.714
• Flash Point 200.6 °C
• Transport Information UN 2735
• Appearance Yellowish clear liquid
• Safety 26-28-36/37/39-45
• Risk Codes 34
• Molecular Structure
• Hazard Symbols C
• Synonyms 3,13-Dioxa-8-aza-4,12-disilapentadecane,4,4,12,12-tetraethoxy- (6CI,8CI);Silane, [iminobis(trimethylene)]bis[triethoxy-(8CI);3,3'-Bis(triethoxysilyl)propylamine;Bis(3-methoxysilylpropyl)amine;Bis(triethoxysilylpropyl)amine;Dynasylan1122;G 402;G 402 (coupling agent);Si 252;
• PSA 67.41000
• LogP 3.84390

Synthetic route

5089-70-3

(3-chloropropyl)triethoxysilane

A

13497-18-2

bis-(3-triethoxysilylpropyl)amine

B

tris-<3-triethoxysilanyl-propyl>-amine and 3-triethoxysilanyl-propylamine

tris-<3-triethoxysilanyl-propyl>-amine and 3-triethoxysilanyl-propylamine

Conditions

Conditions	Yield
With ammonia

919-30-2

3-aminopropyltriethoxysilane

5089-70-3

(3-chloropropyl)triethoxysilane

13497-18-2

bis-(3-triethoxysilylpropyl)amine

Conditions

Conditions	Yield
at 70℃; for 5.5h; Inert atmosphere;	482 g

13497-18-2

bis-(3-triethoxysilylpropyl)amine

109-70-6

1,3-chlorobromopropane

3-chloro-N,N-bis(3-(triethoxysilyl)propyl)propane-1-amine

Conditions

Conditions	Yield
With calcium hydride In N,N-dimethyl-formamide at 23℃; for 15h; Reagent/catalyst;	99%
With calcium hydride In N,N-dimethyl-formamide at 23℃; for 15h;	99%

3121-61-7

2-methoxyethyl acrylate

13497-18-2

bis-(3-triethoxysilylpropyl)amine

2-methoxyethyl 3-(bis(3-triethoxysilylpropyl)amino)propanoate

Conditions

Conditions	Yield
In ethanol at 20℃; for 8h; Inert atmosphere;	97.3%

1003-10-7

Thiobutyrolactone

13497-18-2

bis-(3-triethoxysilylpropyl)amine

1333386-63-2

4-mercapto-N,N-bis(3-(triethoxysilyl)propyl)butanamide

Conditions

Conditions	Yield
In toluene for 48h; Reflux; Inert atmosphere;	96%

50-00-0

formaldehyd

64-17-5

ethanol

13497-18-2

bis-(3-triethoxysilylpropyl)amine

1440531-01-0

N-(ethoxymethyl)-N,N-bis(3-triethoxysilylpropyl)amine

Conditions

Conditions	Yield
at 80℃; for 0.0833333h; Inert atmosphere;	95%
at 80℃; for 0.0833333h; Inert atmosphere;	95 mg

...Expand

13497-18-2

bis-(3-triethoxysilylpropyl)amine

106-96-7

propargyl bromide

N,N-bis((3-triethoxysilyl)propyl)prop-2-yn-1-amine

Conditions

Conditions	Yield
With calcium hydride In tetrahydrofuran; water; toluene at 20℃; Inert atmosphere; Schlenk technique;	95%
In tetrahydrofuran; water; toluene at 20℃;	95%
With calcium hydride In tetrahydrofuran; water; toluene at 20℃; for 16h;	95%

42059-30-3

1-azido-2-iodoethane

13497-18-2

bis-(3-triethoxysilylpropyl)amine

N‐(2‐azidoethyl)‐3‐(triethoxysilyl)‐N‐(3‐(triethoxysilyl)propyl)propan‐1‐amine

Conditions

Conditions	Yield
With potassium carbonate In acetonitrile at 85℃; for 16h; Inert atmosphere; Schlenk technique; Sealed tube;	95%
With potassium carbonate In acetonitrile at 85℃; for 18h; Sealed tube; Inert atmosphere;

13497-18-2

bis-(3-triethoxysilylpropyl)amine

71321-16-9

3-(trimethylsilyl)prop-2-yn-1-yl 4-methylbenzenesulfonate

(3-trimethylsilylprop-2-ynyl)bis(3-triethoxysilylpropyl)amine

Conditions

Conditions	Yield
With potassium carbonate In acetonitrile at 85℃; for 15h;	94%

13497-18-2

bis-(3-triethoxysilylpropyl)amine

phenoxy tetraethyleneglycol acrylate

2-(2-(2-(2-phenoxyethoxy)ethoxy)ethoxy)ethyl 3-(bis(3-(triethoxysilyl)propyl)amino)propanoate

Conditions

Conditions	Yield
In ethanol at 20℃; for 8h; Inert atmosphere;	93.7%

13497-18-2

bis-(3-triethoxysilylpropyl)amine

methoxy PEG(350) monoacrylate

2,5,8,11,14,17,20,23,26-nonaoxaoctacosan-28-yl 3-(bis(3-(triethoxysilyl)propyl)amino)propanoate

Conditions

Conditions	Yield
In ethanol at 20℃; for 8h; Inert atmosphere;	93.5%

13497-18-2

bis-(3-triethoxysilylpropyl)amine

58503-62-1

1-azido-3-iodopropane

3‐azido‐N,N‐bis(3‐(triethoxysilyl)propyl)propan‐1‐amine

Conditions

Conditions	Yield
With potassium carbonate In acetonitrile at 85℃; for 16h; Inert atmosphere; Schlenk technique; Sealed tube;	93%
With potassium carbonate In acetonitrile at 85℃; for 16h; Sealed tube; Inert atmosphere;	93%

2439-35-2

2-(dimethylamino)ethyl methacrylate

13497-18-2

bis-(3-triethoxysilylpropyl)amine

2-(dimethylamino)ethyl 3-(bis(3-triethoxysilylpropyl)amino)propanoate

Conditions

Conditions	Yield
In ethanol at 20℃; for 8h; Inert atmosphere;	91.7%

13497-18-2

bis-(3-triethoxysilylpropyl)amine

48145-04-6

2-phenoxyethyl acrylate

2-phenoxyethyl 3-(bis(3-(triethoxysilyl)propyl)amino)propanoate

Conditions

Conditions	Yield
In ethanol at 20℃; for 8h; Inert atmosphere;	91.6%

13497-18-2

bis-(3-triethoxysilylpropyl)amine

C16H18ClNO4

C34H60N2O10Si2*ClH

Conditions

Conditions	Yield
In dichloromethane at 25℃; for 60h; Inert atmosphere;	81%

13497-18-2

bis-(3-triethoxysilylpropyl)amine

144385-79-5

1-(3-bromopropyl)-1H-imidazole

N-(3-(1H-imidazole-1-yl)propyl)-3-(triethoxysilyl)-N-(3-(triethoxysilyl)propyl)propane-1-amine

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine In acetonitrile at 60℃; for 16h;	65%

13497-18-2

bis-(3-triethoxysilylpropyl)amine

24801-88-5

3-(triethoxypropyl) isocyanate

N,N,N'-tris-(3-triethoxysilylpropyl)urea

Conditions

Conditions	Yield
In methanol for 19h;

13497-18-2

bis-(3-triethoxysilylpropyl)amine

556-52-5

oxiranyl-methanol

C27H55N3O10Si2

Conditions

Conditions	Yield
Stage #1: bis-(3-triethoxysilylpropyl)amine; isophorone diisocyanate In butanone at 10 - 20℃; Stage #2: oxiranyl-methanol In butanone at 20 - 60℃; for 24h;

13497-18-2

bis-(3-triethoxysilylpropyl)amine

18784-74-2

3-(triethoxysilyl)-N,N-bis[3-(triethoxysilyl)propyl]-1-propanamine

Conditions

Conditions	Yield
With hydrogen; palladium on activated charcoal at 195℃; for 12.6667h; Product distribution / selectivity; Inert atmosphere;

13497-18-2

bis-(3-triethoxysilylpropyl)amine

C27H58N4O6Si2

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: calcium hydride / tetrahydrofuran; water; toluene / 20 °C / Inert atmosphere; Schlenk technique 2: bromotris(triphenylphosphine)copper(I); triethylamine / tetrahydrofuran / 24 h / 20 °C / Inert atmosphere; Sealed tube View Scheme
Multi-step reaction with 2 steps 1: tetrahydrofuran; toluene; water / 20 °C 2: triethylamine; [CuBr(PPh3)3] / tetrahydrofuran / 48 h / 20 °C / Inert atmosphere; Schlenk technique View Scheme

13497-18-2

bis-(3-triethoxysilylpropyl)amine

C28H52N4O6Si2

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: calcium hydride / tetrahydrofuran; water; toluene / 20 °C / Inert atmosphere; Schlenk technique 2: bromotris(triphenylphosphine)copper(I); triethylamine / tetrahydrofuran / 0.08 h / 100 °C / Inert atmosphere; Sealed tube; Microwave irradiation View Scheme

13497-18-2

bis-(3-triethoxysilylpropyl)amine

C32H68N4O7Si2

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: calcium hydride / tetrahydrofuran; water; toluene / 20 °C / Inert atmosphere; Schlenk technique 2: bromotris(triphenylphosphine)copper(I); triethylamine / tetrahydrofuran / 0.33 h / 100 °C / Inert atmosphere; Sealed tube; Microwave irradiation View Scheme

13497-18-2

bis-(3-triethoxysilylpropyl)amine

C25H52N4O8Si2

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: calcium hydride / tetrahydrofuran; water; toluene / 20 °C / Inert atmosphere; Schlenk technique 2: bromotris(triphenylphosphine)copper(I); triethylamine / tetrahydrofuran / 0.08 h / 100 °C / Inert atmosphere; Sealed tube; Microwave irradiation View Scheme

13497-18-2

bis-(3-triethoxysilylpropyl)amine

C27H59N4O9PSi2

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: calcium hydride / tetrahydrofuran; water; toluene / 20 °C / Inert atmosphere; Schlenk technique 2: bromotris(triphenylphosphine)copper(I); triethylamine / tetrahydrofuran / 0.17 h / 100 °C / Inert atmosphere; Sealed tube; Microwave irradiation View Scheme

13497-18-2

bis-(3-triethoxysilylpropyl)amine

C30H66N4O9Si3

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: calcium hydride / tetrahydrofuran; water; toluene / 20 °C / Inert atmosphere; Schlenk technique 2: bromotris(triphenylphosphine)copper(I); triethylamine / tetrahydrofuran / 0.33 h / 100 °C / Inert atmosphere; Sealed tube; Microwave irradiation View Scheme

13497-18-2

bis-(3-triethoxysilylpropyl)amine

C29H55N9O6Si2

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: calcium hydride / tetrahydrofuran; water; toluene / 20 °C / Inert atmosphere; Schlenk technique 2: bromotris(triphenylphosphine)copper(I); triethylamine / tetrahydrofuran / 0.17 h / 100 °C / Inert atmosphere; Sealed tube; Microwave irradiation View Scheme

13497-18-2

bis-(3-triethoxysilylpropyl)amine

C52H110N8O12Si4

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: calcium hydride / tetrahydrofuran; water; toluene / 20 °C / Inert atmosphere; Schlenk technique 2: bromotris(triphenylphosphine)copper(I); triethylamine / tetrahydrofuran / 0.33 h / 100 °C / Inert atmosphere; Sealed tube; Microwave irradiation View Scheme

13497-18-2

bis-(3-triethoxysilylpropyl)amine

C50H98N8O12Si4

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: calcium hydride / tetrahydrofuran; water; toluene / 20 °C / Inert atmosphere; Schlenk technique 2: bromotris(triphenylphosphine)copper(I); triethylamine / tetrahydrofuran / 0.17 h / 100 °C / Inert atmosphere; Sealed tube; Microwave irradiation View Scheme

13497-18-2

bis-(3-triethoxysilylpropyl)amine

C26H54N4O8Si2

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: potassium carbonate / acetonitrile / 16 h / 85 °C / Inert atmosphere; Schlenk technique; Sealed tube 2: bromotris(triphenylphosphine)copper(I); triethylamine / tetrahydrofuran / 0.08 h / 100 °C / Inert atmosphere; Sealed tube; Microwave irradiation View Scheme

13497-18-2

bis-(3-triethoxysilylpropyl)amine

C29H55N9O6Si2

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: potassium carbonate / acetonitrile / 16 h / 85 °C / Inert atmosphere; Schlenk technique; Sealed tube 2: bromotris(triphenylphosphine)copper(I); triethylamine / N,N-dimethyl-formamide / 0.08 h / 100 °C / Inert atmosphere; Sealed tube; Microwave irradiation View Scheme

Bis[3-(triethoxysilyl)propyl]amine Chemical Properties

Bis[3-(triethoxysilyl)propyl]amine Safety Profile