Product Name

  • Name

    Bleomycin A5

  • EINECS 234-357-0
  • CAS No. 11116-32-8
  • Density 1.56g/cm3
  • Solubility
  • Melting Point
  • Formula C57H89 N19 O21 S2
  • Boiling Point °Cat760mmHg
  • Molecular Weight 1423.73
  • Flash Point °C
  • Transport Information
  • Appearance
  • Safety Poison by intraperitoneal, intravenous, intramuscular, and subcutaneous routes. Moderately toxic by ingestion. Human systemic effects by an unspecified route: nausea or vomiting, dyspnea, and fever. Mutation data reported. When heated to decomposition it emits very toxic fumes of SOx and NOx. See other bleomycin entries.
  • Risk Codes
  • Molecular Structure Molecular Structure of 11116-32-8 (Bleomycin A5)
  • Hazard Symbols
  • Synonyms Bleomycetin;Bleomycin A5; NSC 350895; Pingyangmycin A5; Zhengguangmycin A5
  • PSA 721.60000
  • LogP -1.43400

Bleomycin A5 Chemical Properties

Chemical Name: Bleomycin A5
IUPAC NAME: [2-[2-[2-[[6-amino-2-[3-amino-1-[(2,3-diamino-3-oxopropyl)amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[[5-[[1-[2-[4-[4-[3-(4-aminobutylamino)propylcarbamoyl]-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-hydroxy-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate
CAS No.: 11116-32-8
EINECS: 234-357-0
Molecular Formula: C57H89N19O21S2
Molecular Weight: 1440.56 g/mol
Density: 1.56 g/cm3
The chemical synonymous of Bleomycin A5 (CAS No.11116-32-8) are Bleomycinamide, N1-[3-[(4-Aminobutyl)Amino]Propyl]- ; Bleomycetin ; Bleomycin A5 ; N1-(3-((4-Aminobutyl)Amino)Propyl)Bleomycinamide ; Pingyangmycin A5 ; Zhengguanmycin A5

Bleomycin A5 Toxicity Data With Reference

1.    

cyt-ham:ovr 400 µg/L

     HKXUDL    Huanjing Kexue Xuebao. Environmental Sciences Journal. 3 (1983),78.
2.    

sce-ham:ovr 400 µg/L

     HKXUDL    Huanjing Kexue Xuebao. Environmental Sciences Journal. 3 (1983),78.
3.    

unr-hmn TDLo:192 mg/kg:GIT,PUL,MET

     ANTBAL    Antibiotiki. 28 (8)(1983),632.
4.    

ipr-rat LD50:117 mg/kg

     ANTBAL    Antibiotiki. 24 (5)(1979),363.
5.    

ivn-rat LD50:100 mg/kg

     ANTBAL    Antibiotiki. 24 (5)(1979),363.
6.    

ims-rat LD50:102 mg/kg

     ANTBAL    Antibiotiki. 24 (5)(1979),363.
7.    

orl-mus LD50:840 mg/kg

     ANTBAL    Antibiotiki. 24 (5)(1979),363.
8.    

ipr-mus LD50:88 mg/kg

     ANTBAL    Antibiotiki. 24 (5)(1979),363.
9.    

scu-mus LD50:77 mg/kg

     ANTBAL    Antibiotiki. 24 (5)(1979),363.
10.    

ivn-mus LD50:61,500 µg/kg

     ANTBAL    Antibiotiki. 24 (5)(1979),363.

Bleomycin A5 Safety Profile

Poison by intraperitoneal, intravenous, intramuscular, and subcutaneous routes. Moderately toxic by ingestion. Human systemic effects by an unspecified route: nausea or vomiting, dyspnea, and fever. Mutation data reported. When heated to decomposition it emits very toxic fumes of SOx and NOx. See other bleomycin entries.

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