Product Name

  • Name

    BUTYL-BIGUANIDE HYDROCHLORIDE

  • EINECS 214-723-6
  • CAS No. 1190-53-0
  • Article Data1
  • CAS DataBase
  • Density
  • Solubility Freely sol in water, alcohol
  • Melting Point 174-177ºC
  • Formula C6H15 N5 . Cl H
  • Boiling Point 322.7 °C at 760 mmHg
  • Molecular Weight 193.68
  • Flash Point 148.9 °C
  • Transport Information
  • Appearance
  • Safety A poison via ingestion, intravenous, and intraperitoneal routes. When heated to decomposition it emits very toxic fumes of HCl and NOx.
  • Risk Codes 22-43-36
  • Molecular Structure Molecular Structure of 1190-53-0 (BUTYL-BIGUANIDE HYDROCHLORIDE)
  • Hazard Symbols
  • Synonyms Biguanide,1-butyl-, monohydrochloride (8CI); Imidodicarbonimidic diamide, N-butyl-,monohydrochloride (9CI); 1-Butylbiguanide hydrochloride; 1-Butylbiguanide,monohydrochloride; 1-Butyldiguanide hydrochloride; Andere; Biforon; Bigunal;Bufonamin; Buformin hydrochloride; Bulbonin; Diabrin; Dibetos; Glibutide;Gliporal; Glybutide; Insulamin; Krebon; N-Butylbiguanide hydrochloride;N1-Butyl-biguanide hydrochloride; N1-n-Butylbiguanide hydrochloride; Panformin;Sindiatil; Tidemol; Ziavetine
  • PSA 97.78000
  • LogP 2.27750

Buformin hydrochloride Chemical Properties

Chemistry informtion about N-Butylbiguanide Hydrochloride (CAS NO.1190-53-0) is:
IUPAC Name: 2-Butyl-1-(Diaminomethylidene)Guanidine
Synonyms: Buformine Hcl ; Buformine Hydrochloride ; Butyl-Biguanide Hydrochloride ; N-Butyl Biguanide Hydrochloride ; 1-Butylbiguanide Monohydrochloride ; N-Butylbiguanidehcl ; 1-Butylbigyanidine Hydrochloride
MF: C6H16ClN5
MW: 193.68
EINECS: 214-723-6 
Flash Point: 148.9 °C
Boiling Point: 322.7 °C at 760 mmHg
Vapour Pressure: 0.000275 mmHg at 25°C
Enthalpy of Vaporization: 56.45 kJ/mol
Following is the molecular structure of N-Butylbiguanide Hydrochloride (CAS NO.1190-53-0) is:

Buformin hydrochloride Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 oral 58mg/kg (58mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 12, Pg. 314, 1962.
guinea pig LD50 subcutaneous 23mg/kg (23mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 12, Pg. 314, 1962.
human TDLo oral 2857ug/kg (2.857mg/kg)

blood: other changes

 Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 7, Pg. 1504, 1965.
mouse LD50 intraperitoneal 74mg/kg (74mg/kg) behavioral: somnolence (general depressed activity) behavioral: convulsions or effect on seizure threshold lungs, thorax, or respiration: respiratory stimulation Toksikologicheskii Vestnik. Vol. (2), Pg. 41, 1993.
mouse LD50 intravenous 105mg/kg (105mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 12, Pg. 314, 1962.
mouse LD50 oral 380mg/kg (380mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 12, Pg. 314, 1962.
rat LD50 oral 320mg/kg (320mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 12, Pg. 314, 1962.

Buformin hydrochloride Safety Profile

A poison via ingestion, intravenous, and intraperitoneal routes. When heated to decomposition it emits very toxic fumes of HCl and NOx.

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