CINNAMAMIDE supplier | CasNO.621-79-4

Name
Cinnamamide
EINECS 210-707-8
CAS No. 621-79-4
Article Data308
CAS DataBase
Density 1.121 g/cm³
Solubility
Melting Point 148-150 °C(lit.)
Formula C₉H₉NO
Boiling Point 350.3 °C at 760 mmHg
Molecular Weight 147.177
Flash Point 165.6 °C
Transport Information
Appearance off-white to beige crystalline powder
Safety 36
Risk Codes 22
Molecular Structure
Hazard Symbols Xn
Synonyms 2-Propenamide, 3-phenyl-;3-Phenylpropenamide;2-Benzylideneacetamide;Cinnamic amide;3-Phenyl-2-propenamide;Ginnamic acid amide;3-Phenylacrylamide;Cinnamyl amide;
PSA 43.09000
LogP 1.88540

CINNAMAMIDE Chemical Properties

IUPAC Name: 3-Phenylprop-2-enamide
Synonyms: Timtec-bb sbb004096 ; Trans-cinnamamide ; Trans-3-Phenylacrylamide ; Cinnamamide ; 3-Phenylacrylamide ; (2E)-3-Phenyl-2-propenamide ;2-Benzylideneacetamide;2-Propenamide, 3-phenyl-
CAS: 621-79-4
MF: C₉H₉NO
MW: 147.17
MS:
EINECS: 210-707-8
Product Categories: Pharmaceutical Intermediates ; Aromatic Carboxylic Acids , Amides , Anilides , Anhydrides & Salts ; Amides ; Carbonyl Compounds ; Organic Building Blocks
Mol File: 621-79-4.mol
Surface Tension: 47.4 dyne/cm
Density: 1.121 g/cm³
Flash Point: 165.6 °C
Enthalpy of Vaporization: 59.49 kJ/mol
Boiling Point: 350.3 °C at 760 mmHg
Vapour Pressure: 4.44E-05 mmHg at 25°C
MP:148-150 °C(lit.)

CINNAMAMIDE Uses

1.Cinnamamide (621-79-4) is a cinnamamide derivative of the formula (wherein X is a halogen atom) is useful as a muscle relaxant and is used in the manufacture of pharmaceutical compositions for relaxing muscle tone.
2.Cinnamamide (621-79-4) is used in organic synthesis intermediate.

CINNAMAMIDE Production

1.Cinnamamide (621-79-4) is derived from cinnamic acid by chlorination, amidation..
2..The use of GUI acid and dichloro-sulfoxide at 60-70 ℃ to react 3-4h, get raw product which need distilled to obtain cinnamon chloride.
3.add Cinnamon chloride slowly to the ammonia of high concentration below 30 ℃, reactiing with stirring 1h.
4.set it 24h, poured into a large number of distilled water, centrifugal drying, washing, re-crystallization by using dilute ethanol to derive product.

CINNAMAMIDE Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	oral	1600mg/kg (1600mg/kg)		Chimica Therapeutica. Vol. 8, Pg. 202, 1973.
rabbit	LDLo	intravenous	62mg/kg (62mg/kg)		Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. Vol. 153, Pg. 895, 1911.

CINNAMAMIDE Safety Profile

Hazard Codes: Xn
Risk Statements: 22
22: Harmful if swallowed
Safety Statements: 36
36: Wear suitable protective clothing
WGK Germany: 3
RTECS: GD6853000

CINNAMAMIDE Specification

Cinnamamide (621-79-4) is white crystals,insoluble in cold water, slightly soluble in hot water, soluble in ether and carbon disulfide.

Product Name

Cinnamamide