Product Name

  • Name

    Citraconic acid

  • EINECS 207-858-7
  • CAS No. 498-23-7
  • Article Data52
  • CAS DataBase
  • Density 1.388 g/cm3
  • Solubility FREELY SOLUBLE
  • Melting Point 88-94 °C(lit.)
  • Formula C5H6O4
  • Boiling Point 336.554 °C at 760 mmHg
  • Molecular Weight 130.1
  • Flash Point 171.546 °C
  • Transport Information
  • Appearance Hygroscopic, off-white powder.
  • Safety 36-37/39-26
  • Risk Codes 22-36/37/38
  • Molecular Structure Molecular Structure of 498-23-7 (Citraconic acid)
  • Hazard Symbols HarmfulXn
  • Synonyms (Z)-2-Methyl-2-butenedioicacid;Methylmaleic acid;
  • PSA 74.60000
  • LogP 0.10190

Synthetic route

diethyl citraconate
691-83-8

diethyl citraconate

citraconic acid
498-23-7

citraconic acid

Conditions
ConditionsYield
With lithium hydroxide In tetrahydrofuran at 20℃; for 8h; Inert atmosphere;84%
2-methylenesuccinic acid
97-65-4

2-methylenesuccinic acid

A

poly(methacrylic acid)
79-41-4

poly(methacrylic acid)

B

citraconic acid
498-23-7

citraconic acid

C

Mesaconic acid
498-24-8

Mesaconic acid

Conditions
ConditionsYield
With 5% Pt/Al2O3; sodium hydroxide In water at 250℃; for 1h; Reagent/catalyst; Temperature; Inert atmosphere;A 68%
B n/a
C n/a
With sodium hydroxide In water at 180℃; under 112511 Torr; for 0.241667h;A 27.26 %Spectr.
B 36.48 %Spectr.
C 16.23 %Spectr.
With sodium hydroxide at 280℃; for 0.0583333h;A 57.08 %Chromat.
B 5.91 %Chromat.
C 5.72 %Chromat.
With sodium hydroxide at 250℃; for 0.25h; Reagent/catalyst;
citric acid
77-92-9

citric acid

A

poly(methacrylic acid)
79-41-4

poly(methacrylic acid)

B

citraconic acid
498-23-7

citraconic acid

C

Mesaconic acid
498-24-8

Mesaconic acid

D

2-methylenesuccinic acid
97-65-4

2-methylenesuccinic acid

Conditions
ConditionsYield
With 4-methoxy-phenol; triphenylphosphine In water at 225℃; under 20686.5 Torr; for 1.5h; Temperature; Glovebox; Inert atmosphere;A 24.1%
B n/a
C n/a
D n/a
With sodium hydroxide at 250℃; for 0.25h; Reagent/catalyst;
LACTIC ACID
849585-22-4

LACTIC ACID

citraconic acid
498-23-7

citraconic acid

Conditions
ConditionsYield
at 250 - 260℃;
Mesaconic acid
498-24-8

Mesaconic acid

citraconic acid
498-23-7

citraconic acid

Conditions
ConditionsYield
With acetyl chloride
Irradiation.UV-Licht;
at 250℃;
2-(2-hydroxy-1-oxopropoxy)propionic acid
617-57-2

2-(2-hydroxy-1-oxopropoxy)propionic acid

citraconic acid
498-23-7

citraconic acid

Conditions
ConditionsYield
at 250 - 260℃;
2-methylenesuccinic acid
97-65-4

2-methylenesuccinic acid

citraconic acid
498-23-7

citraconic acid

Conditions
ConditionsYield
Citraconsaeureanhydrid entsteht bei der Destillation;
Multi-step reaction with 2 steps
1: water / 180 - 200 °C
2: 250 °C
View Scheme
With sodium hydroxide In water at 190℃; under 112511 Torr; for 0.0666667h; Temperature;25.32 %Spectr.
citraconic acid anhydride
616-02-4

citraconic acid anhydride

citraconic acid
498-23-7

citraconic acid

Conditions
ConditionsYield
With water Equilibrium constant; pH = 0.3;
With water Kinetik der Bildung;
With water
itaconic acid anhydride
2170-03-8

itaconic acid anhydride

citraconic acid
498-23-7

citraconic acid

Conditions
ConditionsYield
Citraconsaeureanhydrid entsteht bei der Destillation;
citric acid
77-92-9

citric acid

citraconic acid
498-23-7

citraconic acid

Conditions
ConditionsYield
bei der Destillation; auch ihr Anhydrid entsteht; unter intermediaerer Bildung von Itaconsaeureanhydrid;
With hydrogen iodide
man destilliert und laesst auf das gebildete Citraconsaeureanhydrid Wasser in der Kaelte einwirken;
Thermolysis.und Behandlung des Anhydrids mit Wasser;
citric acid
77-92-9

citric acid

A

citraconic acid
498-23-7

citraconic acid

B

1 propene 1,2,3 tricarboxylic acid
499-12-7

1 propene 1,2,3 tricarboxylic acid

Conditions
ConditionsYield
With hydrogen iodide
citric acid
77-92-9

citric acid

A

citraconic acid
498-23-7

citraconic acid

B

2-methylenesuccinic acid
97-65-4

2-methylenesuccinic acid

Conditions
ConditionsYield
at 170 - 280℃; unter vermindertem Druck;
With water at 280 - 300℃; under 30 - 40 Torr;
3-methyl-2,4-hexadienedioic acid
31659-59-3, 76799-85-4, 116672-65-2, 17110-47-3

3-methyl-2,4-hexadienedioic acid

A

citraconic acid
498-23-7

citraconic acid

B

2-methylbutanedioic acid
498-21-5, 636-60-2

2-methylbutanedioic acid

C

2-hydroxy-2-methylbutane-1,4-dioic acid
597-44-4

2-hydroxy-2-methylbutane-1,4-dioic acid

D

2-hydroxy-2-methylpropanedioic acid
595-48-2

2-hydroxy-2-methylpropanedioic acid

Conditions
ConditionsYield
With sodium hydroxide; dihydrogen peroxide at 90℃; for 4h; Product distribution; var. conc. of H2O2 and NaOH, var. time;
citraconic acid anhydride
616-02-4

citraconic acid anhydride

A

citraconic acid
498-23-7

citraconic acid

B

Citraconyl phosphate

Citraconyl phosphate

Conditions
ConditionsYield
With dipotassium hydrogenphosphate In chloroform; water Mechanism; pH 0.3; pH 10.0;
diethyl citraconate
691-83-8

diethyl citraconate

citraconic acid
498-23-7

citraconic acid

Conditions
ConditionsYield
With lithium hydroxide In tetrahydrofuran at 20℃; for 8h; Inert atmosphere;84%
2-methylenesuccinic acid
97-65-4

2-methylenesuccinic acid

A

poly(methacrylic acid)
79-41-4

poly(methacrylic acid)

B

citraconic acid
498-23-7

citraconic acid

C

Mesaconic acid
498-24-8

Mesaconic acid

Conditions
ConditionsYield
With 5% Pt/Al2O3; sodium hydroxide In water at 250℃; for 1h; Reagent/catalyst; Temperature; Inert atmosphere;A 68%
B n/a
C n/a
With sodium hydroxide In water at 180℃; under 112511 Torr; for 0.241667h;A 27.26 %Spectr.
B 36.48 %Spectr.
C 16.23 %Spectr.
With sodium hydroxide at 280℃; for 0.0583333h;A 57.08 %Chromat.
B 5.91 %Chromat.
C 5.72 %Chromat.
With sodium hydroxide at 250℃; for 0.25h; Reagent/catalyst;
citric acid
77-92-9

citric acid

A

poly(methacrylic acid)
79-41-4

poly(methacrylic acid)

B

citraconic acid
498-23-7

citraconic acid

C

Mesaconic acid
498-24-8

Mesaconic acid

D

2-methylenesuccinic acid
97-65-4

2-methylenesuccinic acid

Conditions
ConditionsYield
With 4-methoxy-phenol; triphenylphosphine In water at 225℃; under 20686.5 Torr; for 1.5h; Temperature; Glovebox; Inert atmosphere;A 24.1%
B n/a
C n/a
D n/a
With sodium hydroxide at 250℃; for 0.25h; Reagent/catalyst;
LACTIC ACID
849585-22-4

LACTIC ACID

citraconic acid
498-23-7

citraconic acid

Conditions
ConditionsYield
at 250 - 260℃;
Mesaconic acid
498-24-8

Mesaconic acid

citraconic acid
498-23-7

citraconic acid

Conditions
ConditionsYield
With acetyl chloride
Irradiation.UV-Licht;
at 250℃;
2-(2-hydroxy-1-oxopropoxy)propionic acid
617-57-2

2-(2-hydroxy-1-oxopropoxy)propionic acid

citraconic acid
498-23-7

citraconic acid

Conditions
ConditionsYield
at 250 - 260℃;
2-methylenesuccinic acid
97-65-4

2-methylenesuccinic acid

citraconic acid
498-23-7

citraconic acid

Conditions
ConditionsYield
Citraconsaeureanhydrid entsteht bei der Destillation;
Multi-step reaction with 2 steps
1: water / 180 - 200 °C
2: 250 °C
View Scheme
With sodium hydroxide In water at 190℃; under 112511 Torr; for 0.0666667h; Temperature;25.32 %Spectr.
citraconic acid anhydride
616-02-4

citraconic acid anhydride

citraconic acid
498-23-7

citraconic acid

Conditions
ConditionsYield
With water Equilibrium constant; pH = 0.3;
With water Kinetik der Bildung;
With water
itaconic acid anhydride
2170-03-8

itaconic acid anhydride

citraconic acid
498-23-7

citraconic acid

Conditions
ConditionsYield
Citraconsaeureanhydrid entsteht bei der Destillation;
citric acid
77-92-9

citric acid

citraconic acid
498-23-7

citraconic acid

Conditions
ConditionsYield
bei der Destillation; auch ihr Anhydrid entsteht; unter intermediaerer Bildung von Itaconsaeureanhydrid;
With hydrogen iodide
man destilliert und laesst auf das gebildete Citraconsaeureanhydrid Wasser in der Kaelte einwirken;
Thermolysis.und Behandlung des Anhydrids mit Wasser;
citric acid
77-92-9

citric acid

A

citraconic acid
498-23-7

citraconic acid

B

1 propene 1,2,3 tricarboxylic acid
499-12-7

1 propene 1,2,3 tricarboxylic acid

Conditions
ConditionsYield
With hydrogen iodide
citric acid
77-92-9

citric acid

A

citraconic acid
498-23-7

citraconic acid

B

2-methylenesuccinic acid
97-65-4

2-methylenesuccinic acid

Conditions
ConditionsYield
at 170 - 280℃; unter vermindertem Druck;
With water at 280 - 300℃; under 30 - 40 Torr;
3-methyl-2,4-hexadienedioic acid
31659-59-3, 76799-85-4, 116672-65-2, 17110-47-3

3-methyl-2,4-hexadienedioic acid

A

citraconic acid
498-23-7

citraconic acid

B

2-methylbutanedioic acid
498-21-5, 636-60-2

2-methylbutanedioic acid

C

2-hydroxy-2-methylbutane-1,4-dioic acid
597-44-4

2-hydroxy-2-methylbutane-1,4-dioic acid

D

2-hydroxy-2-methylpropanedioic acid
595-48-2

2-hydroxy-2-methylpropanedioic acid

Conditions
ConditionsYield
With sodium hydroxide; dihydrogen peroxide at 90℃; for 4h; Product distribution; var. conc. of H2O2 and NaOH, var. time;
citraconic acid anhydride
616-02-4

citraconic acid anhydride

A

citraconic acid
498-23-7

citraconic acid

B

Citraconyl phosphate

Citraconyl phosphate

Conditions
ConditionsYield
With dipotassium hydrogenphosphate In chloroform; water Mechanism; pH 0.3; pH 10.0;
2-Methoxy-4-methylphenol
93-51-6

2-Methoxy-4-methylphenol

A

citraconic acid
498-23-7

citraconic acid

B

2-methylbutanedioic acid
498-21-5, 636-60-2

2-methylbutanedioic acid

C

2-hydroxy-2-methylbutane-1,4-dioic acid
597-44-4

2-hydroxy-2-methylbutane-1,4-dioic acid

D

malonic acid
141-82-2

malonic acid

E

3-methyl-2,4-hexadienedioic acid
31659-59-3, 76799-85-4, 116672-65-2, 17110-47-3

3-methyl-2,4-hexadienedioic acid

F

oxalic acid
144-62-7

oxalic acid

Conditions
ConditionsYield
With sodium hydroxide; oxygen at 45℃; under 63755.1 Torr; for 1.5h; Product distribution; Mechanism; var. temp., time, O2 pressure, conc. and amount of NaOH, different amounts of creosol;
2-methoxy-6-methyl-1,4-benzoquinone
611-68-7

2-methoxy-6-methyl-1,4-benzoquinone

A

citraconic acid
498-23-7

citraconic acid

B

methoxy-maleic acid
2509-15-1

methoxy-maleic acid

C

2-methoxy-6-methylbenzene-1,4-diol
28814-66-6

2-methoxy-6-methylbenzene-1,4-diol

D

α-methyl-α-epoxy-γ-butyric acid

α-methyl-α-epoxy-γ-butyric acid

Conditions
ConditionsYield
With sodium hydroxide; sodium silicate; diethylenetriaminopentaacetic acid; dihydrogen peroxide In water at 25℃; for 1h; Mechanism; pH 9.0;
4-hydroxy-2-methoxy-4-methyl-2,5-cyclohexadien-1-one
42860-79-7

4-hydroxy-2-methoxy-4-methyl-2,5-cyclohexadien-1-one

A

citraconic acid
498-23-7

citraconic acid

B

2-methylbutanedioic acid
498-21-5, 636-60-2

2-methylbutanedioic acid

C

2-hydroxy-2-methylbutane-1,4-dioic acid
597-44-4

2-hydroxy-2-methylbutane-1,4-dioic acid

D

2-hydroxy-2-methylpropanedioic acid
595-48-2

2-hydroxy-2-methylpropanedioic acid

Conditions
ConditionsYield
With sodium hydroxide; air at 90℃; for 2h; Product distribution; var. temp. and time, further reagent: 3percent H2O2;
CYANAMID
420-04-2

CYANAMID

2-Methoxy-4-methylphenol
93-51-6

2-Methoxy-4-methylphenol

A

citraconic acid
498-23-7

citraconic acid

B

5-hydroxy-4-methoxy-2-methyl-phenyl-cyanamide

5-hydroxy-4-methoxy-2-methyl-phenyl-cyanamide

Conditions
ConditionsYield
With dihydrogen peroxide In water at 20℃; for 0.5h; Oxidation;
2-Methoxy-4-methylphenol
93-51-6

2-Methoxy-4-methylphenol

A

citraconic acid
498-23-7

citraconic acid

B

oxalic acid
144-62-7

oxalic acid

C

3'-methoxy-5,5'-dimethyl-biphenyl-2,3,2'-triol

3'-methoxy-5,5'-dimethyl-biphenyl-2,3,2'-triol

D

2-methoxy-6-(2-methoxy-4-methylphenoxy)-4-methylphenol

2-methoxy-6-(2-methoxy-4-methylphenoxy)-4-methylphenol

Conditions
ConditionsYield
With sodium hydroxide; copper(II) ion; dihydrogen peroxide at 80℃; for 2h; Product distribution; Further Variations:; other metal ions; also without metal ion; Oxidation; decomposition;
2,2'-dihydroxy-3,3'-dimethoxy-5,5'-dimethyl-diphenylmethane
1620-70-8

2,2'-dihydroxy-3,3'-dimethoxy-5,5'-dimethyl-diphenylmethane

A

citraconic acid
498-23-7

citraconic acid

B

3-(2-hydroxy-3-methoxy-5-methyl-benzyl)-5-methyl-benzene-1,2-diol

3-(2-hydroxy-3-methoxy-5-methyl-benzyl)-5-methyl-benzene-1,2-diol

C

2-[(2-hydroxy-3-methoxy-5-methylphenyl)methyl]-4-oxopentanoic acid

2-[(2-hydroxy-3-methoxy-5-methylphenyl)methyl]-4-oxopentanoic acid

D

2,5-dihydro-4-[(2-hydroxy-3-methoxy-5-methylphenyl)methyl]-2-methyl-5-oxo-2-furanacetic acid

2,5-dihydro-4-[(2-hydroxy-3-methoxy-5-methylphenyl)methyl]-2-methyl-5-oxo-2-furanacetic acid

Conditions
ConditionsYield
With sodium hydroxide; dihydrogen peroxide; manganese(II) at 80℃; for 2h; Product distribution; Further Variations:; other metal ions; also without metal ion; Oxidation; decomposition;
3,3'-dimethoxy-5,5'-dimethyl-[1,1'-biphenyl]-2,2'-diol
13990-86-8

3,3'-dimethoxy-5,5'-dimethyl-[1,1'-biphenyl]-2,2'-diol

A

citraconic acid
498-23-7

citraconic acid

B

2-methylbutanedioic acid
498-21-5, 636-60-2

2-methylbutanedioic acid

C

2-hydroxy-3-methoxy-5-methylbenzaldehyde
7452-10-0

2-hydroxy-3-methoxy-5-methylbenzaldehyde

D

2-hydroxy-3-methoxy-5-methylbenzoic acid
4386-42-9

2-hydroxy-3-methoxy-5-methylbenzoic acid

Conditions
ConditionsYield
With sodium hydroxide; dihydrogen peroxide; iron(III) at 80℃; for 2h; Product distribution; Further Variations:; other metal ions; also without metal ion; Oxidation; decomposition;
(2,4'-dihydroxy-3,3'-dimethoxy-5-methyl)diphenylmethane
38768-70-6

(2,4'-dihydroxy-3,3'-dimethoxy-5-methyl)diphenylmethane

A

citraconic acid
498-23-7

citraconic acid

B

malic acid
617-48-1

malic acid

C

oxalic acid
144-62-7

oxalic acid

D

maleic acid
110-16-7

maleic acid

Conditions
ConditionsYield
With sodium hydroxide; dihydrogen peroxide; iron(III) at 80℃; for 2h; Product distribution; Further Variations:; other metal ions; also without metal ion; Oxidation; decomposition;
3-maleimide-5-oxime

3-maleimide-5-oxime

sulfuric acid
7664-93-9

sulfuric acid

citraconic acid
498-23-7

citraconic acid

citraconic acid anhydride
616-02-4

citraconic acid anhydride

water
7732-18-5

water

citraconic acid
498-23-7

citraconic acid

3-methylfuran-2-carboxylic acid
4412-96-8

3-methylfuran-2-carboxylic acid

acid sulfomonoperoxoic acid

acid sulfomonoperoxoic acid

citraconic acid
498-23-7

citraconic acid

4-methyl-2,5-dioxo-2,5-dihydro-pyrrole-3-carboxylic acid ethyl ester
98487-98-0

4-methyl-2,5-dioxo-2,5-dihydro-pyrrole-3-carboxylic acid ethyl ester

aq. barium hydroxide solution

aq. barium hydroxide solution

citraconic acid
498-23-7

citraconic acid

5-oxo-1-phenyl-3-pyrrolidinecarboxylic acid
39629-86-2

5-oxo-1-phenyl-3-pyrrolidinecarboxylic acid

A

3-methyl-1-phenylpyrrole-2,5-dione
3120-04-5

3-methyl-1-phenylpyrrole-2,5-dione

B

citraconic acid
498-23-7

citraconic acid

C

2-methylenesuccinic acid
97-65-4

2-methylenesuccinic acid

D

1-phenyl-pyrrolidone-(5)-carboxylic acid-(3)-anilide

1-phenyl-pyrrolidone-(5)-carboxylic acid-(3)-anilide

Conditions
ConditionsYield
at 260℃;
2,3-dimethyl-1H-pyrrole
600-28-2

2,3-dimethyl-1H-pyrrole

Cr2O3-H2SO4

Cr2O3-H2SO4

A

citraconic acid
498-23-7

citraconic acid

B

acetic acid
64-19-7

acetic acid

C

citraconic acid imide

citraconic acid imide

citric acid
77-92-9

citric acid

aluminium phosphate

aluminium phosphate

A

citraconic acid
498-23-7

citraconic acid

B

2-methylenesuccinic acid
97-65-4

2-methylenesuccinic acid

Conditions
ConditionsYield
at 170 - 280℃; unter vermindertem Druck (auch nach Zusatz von anderen Salzen);
methanol
67-56-1

methanol

citraconic acid
498-23-7

citraconic acid

citraconic acid dimethyl ester
617-54-9

citraconic acid dimethyl ester

Conditions
ConditionsYield
With boron trifluoride at 65℃; for 0.333333h;100%
With Bronsted acidic, ionic liquid containing, heteropolyanion functionalized polysiloxane network POS-HPA-IL for 5h; Reflux; Green chemistry;90%
With hydrogenchloride
citraconic acid
498-23-7

citraconic acid

2-methylbutanedioic acid
498-21-5, 636-60-2

2-methylbutanedioic acid

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In tetrahydrofuran; ethanol at 20℃; for 24h; atmospheric pressure;99%
With hydrogen; palladium on activated charcoal In tetrahydrofuran; ethanol at 20℃; for 24h; atmospheric pressure;99%
With 10% Pd/C; hydrogen In tetrahydrofuran; ethanol at 20℃; under 760.051 Torr; for 24h;99%
citraconic acid
498-23-7

citraconic acid

citraconic acid anhydride
616-02-4

citraconic acid anhydride

Conditions
ConditionsYield
With trifluoroacetic anhydride at 20℃; Inert atmosphere;99%
With niobium(V) oxide hydrate In o-xylene at 160℃; for 72h; Inert atmosphere; Molecular sieve;94%
With phosphorus pentoxide In chloroform for 48h; Reflux;80%
citraconic acid
498-23-7

citraconic acid

boron trifluoride diethyl etherate
109-63-7

boron trifluoride diethyl etherate

C5H4BF2O4(1-)*Li(1+)

C5H4BF2O4(1-)*Li(1+)

Conditions
ConditionsYield
With chloro-trimethyl-silane; lithium fluoride; Diethyl carbonate at 60℃; for 6h;99%
citraconic acid
498-23-7

citraconic acid

bis(tri-n-butyltin)oxide
56-35-9

bis(tri-n-butyltin)oxide

citraconic acid tributyltin monoester
145065-44-7, 42735-30-8

citraconic acid tributyltin monoester

Conditions
ConditionsYield
In benzene byproducts: H2O, dicarboxylate; mole ratio of (C4H9)3SnOSn(C4H9)3 and carboxylic acid 1:2; at 20°C or at reflux temp. to remove of water formed by azeotropic distn.;95%
In benzene byproducts: H2O, dicarboxylate; mole ratio of (C4H9)3SnOSn(C4H9)3 and carboxylic acid 1:2; at 20°C or at reflux temp. to remove of water formed by azeotropic distn.;95%
citraconic acid
498-23-7

citraconic acid

diphenyl acetylene
501-65-5

diphenyl acetylene

3-methyl-5,6-diphenyl-(2H)-pyran-2-one

3-methyl-5,6-diphenyl-(2H)-pyran-2-one

Conditions
ConditionsYield
With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; silver carbonate In N,N-dimethyl-formamide at 120℃; for 2h; Inert atmosphere;90%
Butane-1,4-diol
110-63-4

Butane-1,4-diol

citraconic acid
498-23-7

citraconic acid

poly(butylene citraconte), Mn 2.6E3 Da, Mw/Mn 1.5; monomer(s): 1,4-butanediol; citraconic acid

poly(butylene citraconte), Mn 2.6E3 Da, Mw/Mn 1.5; monomer(s): 1,4-butanediol; citraconic acid

Conditions
ConditionsYield
With trifluorormethanesulfonic acid at 60℃; under 0.3 - 3 Torr; for 50h;89%
ethanol
64-17-5

ethanol

citraconic acid
498-23-7

citraconic acid

diethyl citraconate
691-83-8

diethyl citraconate

Conditions
ConditionsYield
With sulfuric acid for 3h; Reflux;88%
With hydrogenchloride
With sulfuric acid; benzene
With phosphorus pentoxide 1.) 0-5 deg C, 2.) reflux, 3 h; Yield given. Multistep reaction;
citraconic acid
498-23-7

citraconic acid

butan-1-ol
71-36-3

butan-1-ol

dibutyl citraconate
22644-92-4

dibutyl citraconate

Conditions
ConditionsYield
With sulfuric acid for 3h; Reflux;81%
citraconic acid
498-23-7

citraconic acid

cobalt(II) diacetate tetrahydrate
6147-53-1

cobalt(II) diacetate tetrahydrate

1,4-bis-(1H-imidazol-1-yl)benzene
25372-07-0

1,4-bis-(1H-imidazol-1-yl)benzene

C5H4O4(2-)*C12H10N4*Co(2+)

C5H4O4(2-)*C12H10N4*Co(2+)

Conditions
ConditionsYield
With sodium hydroxide In water at 120℃; for 96h; Autoclave;79%
barium hydroxide octahydrate

barium hydroxide octahydrate

1,2-diaminocyclohexanepalladium(II)(SO4)

1,2-diaminocyclohexanepalladium(II)(SO4)

citraconic acid
498-23-7

citraconic acid

{1,2-diaminocyclohexanepalladium(II)(citraconate)
119380-18-6

{1,2-diaminocyclohexanepalladium(II)(citraconate)

Conditions
ConditionsYield
In water stirring for 2 h;; filtered; evapd.; elem. anal.;;77%
citraconic acid
498-23-7

citraconic acid

(S)-4-((S)-3-fluoro-3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-yl)-3-(3-(2-methoxyethoxy)phenyl)butanoic acid

(S)-4-((S)-3-fluoro-3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-yl)-3-(3-(2-methoxyethoxy)phenyl)butanoic acid

(S)-4-((S)-3-fluoro-3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-yl)-3-(3-(2-methoxyethoxy)phenyl)butanoic acid citraconate salt

(S)-4-((S)-3-fluoro-3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-yl)-3-(3-(2-methoxyethoxy)phenyl)butanoic acid citraconate salt

Conditions
ConditionsYield
In acetonitrile at 20 - 60℃; for 0.0833333h;77%
palladium(II) acetate trimer
53189-26-7

palladium(II) acetate trimer

citraconic acid
498-23-7

citraconic acid

[Pd(citraconate)(H2O)]n*[0.1(citraconic acid)]n

[Pd(citraconate)(H2O)]n*[0.1(citraconic acid)]n

Conditions
ConditionsYield
In acetone at 20℃; for 6h;75%
[2,2]bipyridinyl
366-18-7

[2,2]bipyridinyl

uranyl nirate hexahydrate

uranyl nirate hexahydrate

citraconic acid
498-23-7

citraconic acid

[UO2(citraconic acid)(2,2'-bipyridine)]

[UO2(citraconic acid)(2,2'-bipyridine)]

Conditions
ConditionsYield
In water at 180℃;72%
citraconic acid
498-23-7

citraconic acid

C10H5Br2NO2S2

C10H5Br2NO2S2

rel-(5R,5aR,11bS)-8,10-dibromo-5-methyl-2,6-dioxo-3,5a,6,11b-tetrahydro-2H,5H-chromeno[4',3':4,5] thiopyrano[2,3-d][1,3]thiazole-5-carboxylic acid

rel-(5R,5aR,11bS)-8,10-dibromo-5-methyl-2,6-dioxo-3,5a,6,11b-tetrahydro-2H,5H-chromeno[4',3':4,5] thiopyrano[2,3-d][1,3]thiazole-5-carboxylic acid

Conditions
ConditionsYield
With acetic acid; hydroquinone for 3h; Diels-Alder Cycloaddition; Reflux; diastereoselective reaction;72%
citraconic acid
498-23-7

citraconic acid

C10H7NO3S2

C10H7NO3S2

rel-(5R,5aR,11bS)-9-hydroxy-5-methyl-2,6-dioxo-3,5a,6,11b-tetrahydro-2H,5H-chromeno[4',3':4,5]thiopyrano[2,3-d][1,3]thiazole-5-carboxylic acid

rel-(5R,5aR,11bS)-9-hydroxy-5-methyl-2,6-dioxo-3,5a,6,11b-tetrahydro-2H,5H-chromeno[4',3':4,5]thiopyrano[2,3-d][1,3]thiazole-5-carboxylic acid

Conditions
ConditionsYield
With acetic acid; hydroquinone for 3h; Diels-Alder Cycloaddition; Reflux; diastereoselective reaction;72%
citraconic acid
498-23-7

citraconic acid

chloroamine-T
127-65-1

chloroamine-T

C12H15NO7S

C12H15NO7S

Conditions
ConditionsYield
71%

CITRACONIC ACID Chemical Properties

 

Product Name: Citraconic acid (CAS NO.498-23-7)


Molecular Formula: C5H6O4
Molecular Weight: 130.1g/mol
Mol File: 498-23-7.mol
Einecs: 207-858-7
Appearance: White to light beige crystalline powder
Melting Point: 88-94 °C(lit.)
Boiling point: 336.6 °C at 760 mmHg
Flash Point: 171.5 °C
Density: 1.387 g/cm3
Water Solubility: Freely soluble
Sensitive: Hygroscopic
Surface Tension: 57.4 dyne/cm
Enthalpy of Vaporization: 63.72 kJ/mol
Vapour Pressure: 2.09E-05 mmHg at 25°C
XLogP3-AA: -0.1
H-Bond Donor: 2
H-Bond Acceptor: 4

CITRACONIC ACID Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 oral 1350mg/kg (1350mg/kg) GASTROINTESTINAL: GASTRITIS Food and Cosmetics Toxicology. Vol. 2, Pg. 327, 1964.
mouse LD50 oral 2260mg/kg (2260mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

GASTROINTESTINAL: OTHER CHANGES
Food and Cosmetics Toxicology. Vol. 2, Pg. 327, 1964.
rat LD50 oral 1320mg/kg (1320mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: TREMOR

GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH
Food and Cosmetics Toxicology. Vol. 2, Pg. 327, 1964.

CITRACONIC ACID Safety Profile

Safety Information of Citraconic acid (CAS NO.498-23-7):
Hazard Codes: Xn
Risk Statements: 22-36/37/38 
22:  Harmful if swallowed
36:  Irritating to the eyes 
37:  Irritating to the respiratory system 
38:  Irritating to the skin 
Safety Statements: 36-37/39-26
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36:  Wear suitable protective clothing 
37:  Wear suitable gloves  
39:  Wear eye/face protection 

CITRACONIC ACID Specification

 Citraconic acid ,its CAS NO. is 498-23-7,the synonyms is (z)-2-Methyl-2-butenedioic acid ; (2z)-2-Methyl-2-butenedioic acid ; Kyselina citrakonova ; Kyselinacitrakonova ; Maleic acid, methyl- ; Methyl-maleicaci ; 2-Methyl-2-butenedioic acid ; Methylmaleic acid .

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View