Product Name

  • Name

    CYMARIN

  • EINECS 208-087-9
  • CAS No. 508-77-0
  • Density 1.31 g/cm3
  • Solubility
  • Melting Point 148ºC
  • Formula C30H44 O9
  • Boiling Point 722.1ºCat 760 mmHg
  • Molecular Weight 548.674
  • Flash Point 232.7 ºC
  • Transport Information
  • Appearance
  • Safety Poison by intravenous, intraperitoneal, and possibly other routes. Used as a cardiotonic. When heated to decomposition it emits acrid smoke and fumes.
  • Risk Codes 23/25-33
  • Molecular Structure Molecular Structure of 508-77-0 (CYMARIN)
  • Hazard Symbols ToxicT
  • Synonyms Cymarin(6CI,7CI,8CI);Alvonal MR;Cymarine;K-Strophanthin-a;NSC 7522;Strophantin K;WV 90043a;
  • PSA 131.75000
  • LogP 2.43330

CYMARIN Chemical Properties

Product Name: Cymarin (CAS NO.508-77-0)


Molecular Formula: C30H44O9
Molecular Weight: 548.66g/mol
Mol File: 508-77-0.mol
Einecs: 208-087-9
Boiling point: 722.1 °C at 760 mmHg
Storage Temperature: 2-8°C
Flash Point: 232.7 °C
Density: 1.31 g/cm3
Surface Tension: 59.4 dyne/cm
Enthalpy of Vaporization: 120.47 kJ/mol
Vapour Pressure: 4.46E-24 mmHg at 25°C
XLogP3: 0.8
H-Bond Donor: 3
H-Bond Acceptor: 9
Product Categories: Cardioglycosides & Glycosides; Carbohydrates; Carbohydrates A to; Carbohydrates P-ZBiochemicals and Reagents; Polysaccharide

CYMARIN Uses

 Cymarin (CAS NO.508-77-0) is a cardiogenic toxin that causes cardiac arrhythmia in humans. Cymarin is used in modern medicine in copiously formulated pharmaceutical preparations used to treat a variety of tumors.

CYMARIN Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LD50 intravenous 95ug/kg (0.095mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 74, Pg. 223, 1942.
cat LD50 parenteral 110ug/kg (0.11mg/kg)   Bollettino Chimico Farmaceutico. Vol. 98, Pg. 297, 1959.
cat LDLo unreported 110ug/kg (0.11mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 148, Pg. 471, 1964.
mouse LD50 intracrebral 41ug/kg (0.041mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 908, 1961.
mouse LD50 intraperitoneal 12mg/kg (12mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 155, Pg. 165, 1965.
mouse LD50 intravenous 2800ug/kg (2.8mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 908, 1961.
rat LD50 intravenous 20mg/kg (20mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 155, Pg. 165, 1965.

CYMARIN Safety Profile

Poison by intravenous, intraperitoneal, and possibly other routes. Used as a cardiotonic. When heated to decomposition it emits acrid smoke and fumes.
Safety Information of Cymarin (CAS NO.508-77-0):
Hazard Codes: T,T+
Risk Statements: 23/25-33-26/27/28 
23:  Toxic by inhalation 
25:  Toxic if swallowed 
26:  Very Toxic by inhalation 
27:  Very Toxic in contact with skin 
28:  Very Toxic if swallowed 
33:  Danger of cumulative effects 
Safety Statements: 45-36/37/39
36:  Wear suitable protective clothing  
37:  Wear suitable gloves 
39:  Wear eye/face protection 
45:  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)

CYMARIN Specification

 Cymarin ,its CAS NO. is 508-77-0,the synonyms is 20(22),5Beta-cardenolid-19-al-3beta,5beta,14beta-triol 3beta-mixed glycosides ; Cimarin ; Cymarine ; k Strophanthin ; k-Strophanthin-a ; k-Strophanthin-alpha ; k-Strophanthidin-d-cymaroside .

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