-
Name
Caerulein
- EINECS
- CAS No. 17650-98-5
- Density 1.406g/cm3
- Solubility
- Melting Point 224-226° (dec)
- Formula C58H73 N13 O21 S2
- Boiling Point °Cat760mmHg
- Molecular Weight 1352.42
- Flash Point °C
- Transport Information
- Appearance
- Safety A poison by subcutaneous route. When heated to decomposition it emits toxic vapors of NOx and SOx.
- Risk Codes
-
Molecular Structure
- Hazard Symbols A poison.
- Synonyms Caerulein1.1; Caerulein 1.1 (Litoria citropa); Cerulein; Ceruletide; FI 6934;L-Phenylalaninamide, 5-oxo-L-prolyl-L-glutaminyl-L-a-aspartyl-O-sulfo-L-tyrosyl-L-threonylglycyl-L-tryptophyl-L-methionyl-L-a-aspartyl-
- PSA 585.08000
- LogP 1.81300
Caerulein Chemical Properties
Chemistry informtion about Caerulein (CAS NO.17650-98-5) is:
Synonyms: [Tyr(So3h)4]Caerulein ; Pglu-Gln-Asp-Tyr[So3h]-Thr-Gly-Trp-Met-Asp-Phe-Nh2 ; Pyroglu-Gln-Asp-Tyr[So3h]-Thr-Gly-Trp-Met-Asp-Phe-Nh2 ; Pyroglu-Gln-Asp-Tyr(So3h)-Thr-Gly-Trp-Met-Asp-Phe-Nh2.2nh3 ; Pyr-Qd-Y(So3h)-Tgwmdf-Nh2 ; Pyr-Gln-Asp-Tyr(So3h)-Thr-Gly-Trp-Met-Asp-Phe-Nh2 ; Glp-Gln-Asp-Tyr(So3h)-Thr-Gly-Trp-Met-Asp-Phe-Nh2 ; Cerulein
MF: C58H73N13O21S2
MW: 1352.4
Density: 1.464 g/cm3
Storage temp.: −20°C
Solubility: 0.05 M ammonium hydroxide: 1 mg/mL, clear, colorless
Merck: 13,2015
Following is the molecular structure of Caerulein (CAS NO.17650-98-5) is:
Caerulein Uses
Caerulein (CAS NO.17650-98-5) is used in paralytic ileus and as diagnostic aid in pancreatic malfunction.
Caerulein Toxicity Data With Reference
| 1. | scu-rat TDLo:20 µg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 293 (2000),670. | ||
| 2. | scu-rat TDLo:80 µg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 293 (2000),670. |
Caerulein Safety Profile
A poison by subcutaneous route. When heated to decomposition it emits toxic vapors of NOx and SOx.
WGK Germany: 3
F:
F 10: Keep under argon.
F 21: Sensitive to humidity.
Caerulein Specification
Caerulein (CAS NO.17650-98-5) is a specific decapeptide obtained from the skin of Litoria caerulea, an Australian amphibian. Caerulein is similar in action and composition to cholecystokinin. It stimulates gastric, biliary, and pancreatic secretion; and certain smooth muscle.
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