-
Name
Carbachol
- EINECS 200-127-3
- CAS No. 51-83-2
- Article Data6
- CAS DataBase
- Density 1.2798 (rough estimate)
- Solubility 1.0 g/mL
- Melting Point 200-204 ºC
- Formula C6H15 N2 O2 . Cl
- Boiling Point
- Molecular Weight 182.65
- Flash Point
- Transport Information UN 2811
- Appearance white crystalline powder
- Safety Deadly poison by subcutaneous, intravenous, and intraperitoneal routes. Poison by ingestion and possibly other routes. Human systemic effects by intravenous and intramuscular routes including: lowered blood pressure, venous dilation, nausea or vomiting, sweating and lachrymation (increased flow of tears). A cholinergic agent (parasympathetic nerve stimulant). When heated to decomposition it emits very toxic fumes of Cl−, NH3, and NOx. See also CARBAMATES.
- Risk Codes R25;R36/37/38
-
Molecular Structure
-
Hazard Symbols
- Synonyms Choline,chloride, carbamate (6CI,8CI); Ethanaminium, 2-[(aminocarbonyl)oxy]-N,N,N-trimethyl-,chloride (9CI); (2-Carbamoyloxyethyl)trimethylammonium chloride;(2-Hydroxyethyl)trimethyl ammonium chloride carbamate; Carbachol; Carbacholchloride; Carbacholin; Carbacholine; Carbacholine chloride; Carbacolina;Carbaminocholine chloride; Carbaminoylcholine chloride; Carbamiotin;Carbamoylcholine chloride; Carbamoylcholine-hydrochloride; Carbamylcholinechloride; Carbastat Intraocular; Carbochol; Carbocholin; Carbocholine; Carbyl;Carcholin; Choline carbamate chloride; Coletyl; Doryl; Doryl (pharmaceutical);Isopto Carbachol; Jestryl; Lentin; Miostat; Moryl; Vasoperif; g-Carbamoyl choline chloride
- PSA 52.32000
- LogP -2.50780
Carbachol Chemical Properties
Carbachol chloride(51-83-2) exists as white crystals, insoluble in CHCl3 and Et2O. Carbachol chloride(51-83-2) has hydroscopic property and smells like fatty amines.
Molecular Structure:
Molecular Formula: C6H15N2O2?Cl.
Molecular Weight: 182.68.
Melting Point: 200-204 ℃.
Solubility(H2O): 1.0 g/mL.
Molecular Structure:
Molecular Formula: C6H15N2O2?Cl.
Molecular Weight: 182.68.
Melting Point: 200-204 ℃.
Solubility(H2O): 1.0 g/mL.
Carbachol Uses
Carbachol chloride(51-83-2) is a kind of cholinergic drugs, and it is also used as parasympathetic stimulant. As a animal remedy, Carbachol chloride(51-83-2) is used for the treatment of intestinal colic.
Carbachol Toxicity Data With Reference
| 1. | ivn-man TDLo:1428 ng/kg:CVS,GIT | CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. 113 (1933),79. | ||
| 2. | ims-hmn TDLo:6 µg/kg:EYE,CVS,SKN | SCALA9 Scalpel. 36 (1933),1. | ||
| 3. | ims-man TDLo:2857 ng/kg:CVS | CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. 113 (1933),79. | ||
| 4. | orl-rat LD50:40 mg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 58 (1936),337. | ||
| 5. | ipr-rat LD50:2 mg/kg | AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. 149 (1964),560. | ||
| 6. | scu-rat LD50:4 mg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 58 (1936),337. | ||
| 7. | ivn-rat LD50:100 µg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 58 (1936),337. | ||
| 8. | orl-mus LD50:15 mg/kg | NIIRDN “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),182. | ||
| 9. | ipr-mus LD50:370 µg/kg | ATXKA8 Archiv fuer Toxikologie. 29 (1972),39. | ||
| 10. | scu-mus LD50:3 mg/kg |
Carbachol Consensus Reports
EPA Extremely Hazardous Substances List. Reported in EPA TSCA Inventory.
Carbachol Safety Profile
Deadly poison by subcutaneous, intravenous, and intraperitoneal routes. Poison by ingestion and possibly other routes. Human systemic effects by intravenous and intramuscular routes including: lowered blood pressure, venous dilation, nausea or vomiting, sweating and lachrymation (increased flow of tears). A cholinergic agent (parasympathetic nerve stimulant). When heated to decomposition it emits very toxic fumes of Cl−, NH3, and NOx. See also CARBAMATES.
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