Molecular Structure:
Molecular Formula: C12H15NO3
Molecular Weight: 221.2524
IUPAC Name: (2,2-Dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate
Synonyms of Carbofuran (CAS NO.1563-66-2): 7-Benzofuranol, 2,3-dihydro-2,2-dimethyl-, 7-(N-methylcarbamate) ; 7-Benzofuranol, 2,3-dihydro-2,2-dimethyl-, methylcarbamate ; Carbamic acid, methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester ; Furadan ; Carbamic acid, methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester
CAS NO: 1563-66-2
Product Categories: Acaricide ; Agricultural Chemical ; Anthelmintics ; Anti-Infective Agents ; Antinematodal agents ; Antiparasitic Agents ; Avicide ; Cholinergic Agents ; Cholinesterase inhibitors ; Enzyme Inhibitors ; Human Data ; Insecticide ; Insecticides ; Mutation data ; Nematocide ; Neurotransmitter Agents ; Pesticides ; Reproductive Effect
Melting point: 150-153 °C
Index of Refraction: 1.525
Molar Refractivity: 59.67 cm3
Molar Volume: 194.4 cm3
Surface Tension: 40.5 dyne/cm
Density: 1.137 g/cm3
Flash Point: 143.3 °C
Enthalpy of Vaporization: 55.43 kJ/mol
Boiling Point: 313.3 °C at 760 mmHg
Vapour Pressure: 0.000502 mmHg at 25°C
Carbofuran (CAS NO.1563-66-2) is one of the few insecticides effective on soybean aphids, which have expanded their range since 2002 to include most soybean-growing regions of the U.S.
Carbofuran (CAS NO.1563-66-2) is used as a systemic insecticide to control insects in a wide variety of field crops.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
bird - wild | LD50 | oral | 420ug/kg (0.42mg/kg) | Toxicology and Applied Pharmacology. Vol. 26, Pg. 154, 1973. | |
bird - wild | LD50 | skin | 100mg/kg (100mg/kg) | Toxicology and Applied Pharmacology. Vol. 26, Pg. 154, 1973. | |
chicken | LD50 | oral | 6300ug/kg (6.3mg/kg) | PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA | Toxicology and Applied Pharmacology. Vol. 11, Pg. 49, 1967. |
dog | LC50 | inhalation | 52mg/m3 (52mg/m3) | SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS GASTROINTESTINAL: NAUSEA OR VOMITING | JOM, Journal of Occupational Medicine. Vol. 12, Pg. 16, 1970. |
dog | LD50 | oral | 19mg/kg (19mg/kg) | SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS GASTROINTESTINAL: NAUSEA OR VOMITING | JOM, Journal of Occupational Medicine. Vol. 12, Pg. 16, 1970. |
duck | LD50 | oral | 415ug/kg (0.415mg/kg) | Toxicology and Applied Pharmacology. Vol. 22, Pg. 556, 1972. | |
guinea pig | LC50 | inhalation | 43mg/m3/4H (43mg/m3) | SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. N5182, Pg. 1967, |
mammal (species unspecified) | LD50 | skin | 837mg/kg (837mg/kg) | SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 53(2), Pg. 89, 1988. |
mouse | LD50 | intravenous | 450ug/kg (0.45mg/kg) | U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#11280, | |
mouse | LD50 | oral | 2mg/kg (2mg/kg) | Journal of Agricultural and Food Chemistry. Vol. 18, Pg. 793, 1970. | |
mouse | LD50 | unreported | 5mg/kg (5mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 49(10), Pg. 23, 1984. | |
pigeon | LD50 | oral | 1330ug/kg (1.33mg/kg) | ASTM Special Technical Publication. Vol. (680), Pg. 157, 1979. | |
quail | LD50 | oral | 3160ug/kg (3.16mg/kg) | ASTM Special Technical Publication. Vol. (680), Pg. 157, 1979. | |
rabbit | LD50 | skin | 885mg/kg (885mg/kg) | Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 81, 1973. | |
rabbit | LD50 | unreported | 885mg/kg (885mg/kg) | "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 192, 1971. | |
rat | LC50 | inhalation | 85mg/m3 (85mg/m3) | SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS GASTROINTESTINAL: NAUSEA OR VOMITING | JOM, Journal of Occupational Medicine. Vol. 12, Pg. 16, 1970. |
rat | LD50 | oral | 5mg/kg (5mg/kg) | Pesticide Science. Vol. 1, Pg. 117, 1970. | |
rat | LD50 | skin | 120mg/kg (120mg/kg) | World Review of Pest Control. Vol. 9, Pg. 119, 1970. | |
rat | LD50 | unreported | 19mg/kg (19mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 49(10), Pg. 23, 1984. | |
women | TDLo | oral | 1200ug/kg (1.2mg/kg) | BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" LUNGS, THORAX, OR RESPIRATION: DYSPNEA SKIN AND APPENDAGES (SKIN): SWEATING: OTHER | Khigiena i Zdraveopazvane. Hygiene and Sanitation. Vol. 24, Pg. 445, 1981. |
Hazard Codes of Carbofuran (CAS NO.1563-66-2): T+,N,T
Risk Statements: 26/28-50/53
R26/28: Very toxic by inhalation and if swallowed.
R50/53: Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: 36/37-45-60-61-1/2
S36/37: Wear suitable protective clothing and gloves.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S60: This material and its container must be disposed of as hazardous waste.
S61: Avoid release to the environment. Refer to special instructions / safety data sheets.
S1/2: Keep locked up and out of the reach of children.
RIDADR: UN 2811 6.1/PG 1
WGK Germany: 3
RTECS: FB9450000
HazardClass: 6.1(a)
PackingGroup: I
The technical or chemical name of Carbofuran is 2,3-dihydro-2,2-dimethyl-7-benzofuranyl methylcarbamate and its CAS number is 1563-66-2 and it is manufactured by reaction of Methyl isocyanate with 2,3-dihydro-2,2-dimethyl-7-hydroxybenzofuran.
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