The IUPAC name of Carteolol hydrochloride (CAS NO.51781-21-6):
5-[3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydro-
Synonyms: 5-(2-Hydroxy-3-tert-butylamino)propoxy-3,4-dihydrocarbostyrilhydrochloride ; 5-(3-((1,1-Dimethylethyl)amino)-2-hydroxypropoxy)-3,4-dihydro-2(1h)-quinolin ; 5-(3-Tert-butylamino-2-hydroxy)propoxy-3,4-dihydrocarbostyrilhydrochloride ; 5-(3-Tert-butylamino-2-hydroxy-propoxy)-3,4-dihydro-2(1h)-chinolinon-hydroch ; Abbott-43326 ; Carbonolol ; Carteololhydrochloride ; Endak
CAS: 51781-21-6
EINECS: 257-415-7
Molecular Formula: C16H25ClN2O3
Molecular Structure:
Formula Weight: 328.83
Flash Point: 267.4 °C
Boiling Point: 518.6 °C at 760 mmHg
Melting point:278°C
The toxicity of Carteolol hydrochloride (CAS NO.51781-21-6):
1. | orl-rat LD50:1330 mg/kg | OYYAA2 Oyo Yakuri. Pharmacometrics. 11 (1976),159. | ||
2. | ipr-rat LD50:390 mg/kg | OYYAA2 Oyo Yakuri. Pharmacometrics. 11 (1976),159. | ||
3. | scu-rat LD50:1950 mg/kg | OYYAA2 Oyo Yakuri. Pharmacometrics. 11 (1976),159. | ||
4. | ivn-rat LD50:153 mg/kg | OYYAA2 Oyo Yakuri. Pharmacometrics. 11 (1976),159. | ||
5. | orl-mus LD50:810 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 33 (1983),290. | ||
6. | ipr-mus LD50:375 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 33 (1983),290. | ||
7. | scu-mus LD50:600 mg/kg | IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 12 (1981),668. | ||
8. | ivn-mus LD50:54,500 µg/kg | IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 12 (1981),668. | ||
9. | orl-dog LD50:830 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 33 (1983),290. | ||
10. | orl-rbt LD50:740 mg/kg | OYYAA2 Oyo Yakuri. Pharmacometrics. 11 (1976),165. |
EPA Genetic Toxicology Program.
The safety information of Carteolol hydrochloride (CAS NO.51781-21-6):
Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and HCl.
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