Product Name

  • Name

    7-[(2-Hydroxy-2-phenylacetyl)amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

  • EINECS 252-030-0
  • CAS No. 34444-01-4
  • Article Data8
  • CAS DataBase
  • Density 1.75 g/cm3
  • Solubility
  • Melting Point
  • Formula C18H18 N6 O5 S2
  • Boiling Point °Cat760mmHg
  • Molecular Weight 462.51
  • Flash Point °C
  • Transport Information
  • Appearance White to off-white powder
  • Safety
  • Risk Codes
  • Molecular Structure Molecular Structure of 34444-01-4 (7-[(2-Hydroxy-2-phenylacetyl)amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid)
  • Hazard Symbols
  • Synonyms 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[(hydroxyphenylacetyl)amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,[6R-[6a,7b(R*)]]-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2R)-hydroxyphenylacetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,(6R,7R)- (9CI);3-(1-Methyltetrazol-5-ylthiomethyl)-7-D-mandelamido-3-cephem-4-carboxylic acid;CMT; Cefadole; Cefamandol; Cefamandole; Cephadole; Cephamandole; L-Cefamandole
  • PSA 201.14000
  • LogP 0.10320

Cefamandole Chemical Properties

Chemistry informtion about Cephamandole (CAS NO.34444-01-4) is:
IUPAC Name: Pentyl nitrite
Synonyms: Cefamandole ; (R*)))- ; 5-Thia-1-Azabicyclo(4.2.0)Oct-2-Ene-2-Carboxylicacid,7-((Hydroxyphenylacetyl) ; Amino)-3-(((1-Methyl-1h-Tetrazol-5-Yl)Thio)Methyl)-8-Oxo-,(6r-(6-Alpha,7-Beta ; Cefadole ; Cefamandol ; Cephadole ; Cephamandole
MF: C18H18N6O5S2
MW: 462.5
EINECS: 252-030-0 
Density: 1.75 g/cm3
Following is the molecular structure of Cephamandole (CAS NO.34444-01-4) is:

Cefamandole Uses

 Cephamandole (CAS NO.34444-01-4) (INN, also known as cephamandole ) is a second-generation broad-spectrum cephalosporin antibiotic. The clinically used form of cefamandole is the formate ester cefamandole nafate, a prodrug which is administered parenterally.It is no longer available in the United States.

Cefamandole Safety Profile

Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and SOx.

Cefamandole Specification

The chemical structure of Cephamandole (CAS NO.34444-01-4) , like that of several other cephalosporins, contains an N-methylthiotetrazole (NMTT or 1-MTT) side chain. As the antibiotic is broken down in the body, it releases free NMTT, which can cause hypoprothrombinemia (likely due to inhibition of the enzyme vitamin K epoxide reductase) and a reaction with ethanol similar to that produced by disulfiram (Antabuse), due to inhibition of aldehyde dehydrogenase.

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