-
Name
Cefatrizine
- EINECS 257-324-2
- CAS No. 51627-14-6
- Density 1.73 g/cm3
- Solubility
- Melting Point
- Formula C18H18N6O5S2
- Boiling Point 948.1 °C at 760 mmHg
- Molecular Weight 538.59 .
- Flash Point 527.2 °C
- Transport Information
- Appearance White to slightly yellowish powder
- Safety
- Risk Codes
-
Molecular Structure
- Hazard Symbols
- Synonyms 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R)-amino(4-hydroxyphenyl)acetyl]amino]-8-oxo-3-[(1H-1,2,3-triazol-4-ylthio)methyl]-,(6R,7R)- (9CI);5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[amino(4-hydroxyphenyl)acetyl]amino]-8-oxo-3-[(1H-1,2,3-triazol-4-ylthio)methyl]-,[6R-[6a,7b(R*)]]-;7-[D-a-Amino-a-(4-hydroxyphenyl)acetamido]-3-(1,2,3-triazol-5-ylthiomethyl)-3-cephem-4-carboxylicacid;Antibiotic BL-S 640;BL-S 640;Cefaperos;Cefatrizine;Cephatrizin;Cepticol;S 640P;SKF 60771;
- PSA 225.13000
- LogP 1.07010
Cefatrizine Chemical Properties
Chemical Name: Cefatrizine
IUPAC NAME: (6R,7R)-7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-
8-oxo-3-(2H-triazol-4-ylsulfanylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-
2-ene-2-carboxylic acid
CAS No.: 51627-14-6
EINECS: 257-324-2
Molecular Formula: C18H18N6O5S2
Molecular Weight: 538.6 g/mol
Density: 1.73 g/cm3
Flash Point: 527.2 °C
Boiling Point: 948.1 °C at 760 mmHg
Following is the structure of ANTIBIOTIC BL-640 (51627-14-6):
The chemical synonymous of ANTIBIOTIC BL-640 (51627-14-6) are CEFATRIZINE ; CEFATRIZINE PROPYLENE GLYCOL ; 7-[2-(4-hydroxyphenyl)-2-aminoacetamido]-3-(1,2,3-triazole-4-ylthio)methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ; antibioticbl-640 ; antibioticbl-s640 ; bls640 ; cephatriazine ; eta(r)))-
Cefatrizine Uses
ANTIBIOTIC BL-640 (51627-14-6) is primarily used to treat liver and gallbladder infections caused by susceptible strains, urinary tract infections, respiratory infections, septicemia, endocarditis and meningitis and other illnesses.
Cefatrizine Toxicity Data With Reference
| 1. | orl-rat TDLo:175 mg/kg (8-14D preg):REP | JJANAX Japanese Journal of Antibiotics. 29 (1976),129. | ||
| 2. | orl-rat TDLo:5600 mg/kg (female 8-14D post):TER | JJANAX Japanese Journal of Antibiotics. 29 (1976),129. | ||
| 3. | orl-rat LD:>6 g/kg | JJANAX Japanese Journal of Antibiotics. 29 (1976),612. | ||
| 4. | ipr-rat LD50:4325 mg/kg | JJANAX Japanese Journal of Antibiotics. 29 (1976),612. | ||
| 5. | ipr-mus LD50:6410 mg/kg | JJANAX Japanese Journal of Antibiotics. 29 (1976),612. | ||
| 6. | ipr-rbt LD50:1500 mg/kg | JJANAX Japanese Journal of Antibiotics. 29 (1976),612. | ||
| 7. | scu-rbt LD50:3000 mg/kg | JJANAX Japanese Journal of Antibiotics. 29 (1976),612. |
Cefatrizine Safety Profile
Moderately toxic by intraperitoneal and subcutaneous routes. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits very highly toxic fumes of NOx and SOx.
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