Product Name

  • Name

    gemeprost

  • EINECS
  • CAS No. 64318-79-2
  • Article Data3
  • CAS DataBase
  • Density 1.08g/cm3
  • Solubility
  • Melting Point
  • Formula C23H38 O5
  • Boiling Point 510.5oC at 760 mmHg
  • Molecular Weight 394.552
  • Flash Point 163.9oC
  • Transport Information
  • Appearance
  • Safety Poison by ingestion, subcutaneous, intravenous, and intravaginal routes. Human reproductive effects by intravaginal route: abortion, changes in the uterus, cervix, and vagina. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits acrid smoke and fumes. See other prostaglandin entries.
  • Risk Codes
  • Molecular Structure Molecular Structure of 64318-79-2 (gemeprost)
  • Hazard Symbols
  • Synonyms 16,16-Dimethyl-trans-D2-PGE methyl ester;16,16-Dimethyl-trans-D2-PGE1 methyl ester; 16,16-Dimethyl-trans-D2-prostaglandin E1 methyl ester; Carprost; Cergem;Cervagem; Cervageme; Gemeprost; Methyl 16,16-dimethyl-trans-D2-PGE1; ONO 802; Preglandin; SC37681; trans-2,3-Didehydro-16,16-dimethyl PGE1 methyl ester
  • PSA 83.83000
  • LogP 3.97560

Cervagem Chemical Properties

Chemistry informtion about Cervagem (CAS NO.64318-79-2) is:
IUPAC Name: Methyl (E)-7-[(1s,2s,3s)-3-Hydroxy-2-[(Z,3r)-3-Hydroxy-4,4-Dimethyloct-1-Enyl]-5-Oxocyclopentyl]Hept-2-Enoate
Synonyms: Gemeprost ; 16,16-Dimethyl-Trans-Δ2-Pge Methyl Ester ; 16,16-Dimethyl-Trans-Δ2-Pge1 Methyl Ester ; 16,16-Dimethyl-Trans-Δ2-Prostaglandin E1 Methyl Ester ; Carprost ; Cergem ; Cervagem ; Cervageme
MF: C23H38O5
MW: 394.544820 g/mol
EINECS: 264-775-9 
Density: 1.08 g/cm3
Flash Point: 163.9 °C
Boiling Point: 510.5 °C at 760 mmHg
Vapour Pressure: 1.47E-12 mmHg at 25°C 
Enthalpy of Vaporization: 89.95 kJ/mol
Following is the molecular structure of Cervagem (CAS NO.64318-79-2) is:

Cervagem Toxicity Data With Reference

Toxic information about Cervagem (CAS NO.64318-79-2) is:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravaginal 36mg/kg (36mg/kg) gastrointestinal: "hypermotility, diarrhea" Gendai Iryo. Modern Medical Care. Vol. 14, Pg. 188, 1982.
mouse LD50 intravenous 29500ug/kg (29.5mg/kg) behavioral: convulsions or effect on seizure threshold behavioral: ataxia lungs, thorax, or respiration: respiratory depression Gendai Iryo. Modern Medical Care. Vol. 14, Pg. 188, 1982.
mouse LD50 oral 59mg/kg (59mg/kg) behavioral: somnolence (general depressed activity) lungs, thorax, or respiration: respiratory depression gastrointestinal: "hypermotility, diarrhea" Gendai Iryo. Modern Medical Care. Vol. 14, Pg. 188, 1982.
mouse LD50 subcutaneous 32500ug/kg (32.5mg/kg) behavioral: altered sleep time (including change in righting reflex) lungs, thorax, or respiration: respiratory depression Gendai Iryo. Modern Medical Care. Vol. 14, Pg. 188, 1982.
rat LD50 intravaginal 32500ug/kg (32.5mg/kg) gastrointestinal: "hypermotility, diarrhea" Gendai Iryo. Modern Medical Care. Vol. 14, Pg. 188, 1982.
rat LD50 intravenous 28600ug/kg (28.6mg/kg) behavioral: convulsions or effect on seizure threshold behavioral: ataxia lungs, thorax, or respiration: respiratory depression Gendai Iryo. Modern Medical Care. Vol. 14, Pg. 188, 1982.
rat LD50 oral 56500ug/kg (56.5mg/kg) behavioral: somnolence (general depressed activity) lungs, thorax, or respiration: respiratory depression gastrointestinal: "hypermotility, diarrhea" Gendai Iryo. Modern Medical Care. Vol. 14, Pg. 188, 1982.
rat LD50 subcutaneous 22600ug/kg (22.6mg/kg) behavioral: altered sleep time (including change in righting reflex) lungs, thorax, or respiration: respiratory depression Gendai Iryo. Modern Medical Care. Vol. 14, Pg. 188, 1982.

Cervagem Safety Profile

Poison by ingestion, subcutaneous, intravenous, and intravaginal routes. Human reproductive effects by intravaginal route: abortion, changes in the uterus, cervix, and vagina. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits acrid smoke and fumes. See other prostaglandin entries. 
RIDADR: 3249
HazardClass: 6.1(b)
PackingGroup: III

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