• Name

  CETYL PALMITATE

• EINECS 208-736-6
• CAS No. 540-10-3
• Article Data39
• CAS DataBase
• Density 0.858 g/cm³
• Solubility
• Melting Point 55-56 °C(lit.)
• Formula C₃₂H₆₄O₂
• Boiling Point 507 °C at 760 mmHg
• Molecular Weight 480.859
• Flash Point 269.8 °C
• Transport Information
• Appearance white to almost white crystalline powder
• Safety 24/25
• Risk Codes
• Molecular Structure
• Hazard Symbols
• Synonyms Palmiticacid, cetyl ester (4CI);Palmitic acid, hexadecyl ester (6CI,7CI,8CI);1-Hexadecanol, palmitate (8CI);Cetin;Cetyl palmitate;Cutina CP;Cutina CPA;Estol 3694;Hexadecyl hexadecanoate;Hexadecyl palmitate;Kessco 653;N-SP;Nikkol N-SP;Nikkol N-SPV;Palmitic acid palmityl ester;Palmityl palmitate;Precifac;Precifac ATO;Radia 7500;S 653;Standamul 1616;Starfol Wax CG;Stepan 653;Stepantex 653;n-Hexadecyl hexadecanoate;n-Hexadecyln-hexadecanoate;
• PSA 26.30000
• LogP 11.49220

Synthetic route

36653-82-4

1-Hexadecanol

57-10-3

1-hexadecylcarboxylic acid

540-10-3

cetyl palmitate

Conditions

Conditions	Yield
With zirconium(IV) oxychloride In 1,3,5-trimethyl-benzene at 162℃; for 24h;	99.5%
hafnium(IV) oxychloride In 1,3,5-trimethyl-benzene at 162℃; for 24h;	98.7%
With choline chloride; zinc(II) chloride at 110℃; for 10h;	97%

36653-82-4

1-Hexadecanol

540-10-3

cetyl palmitate

Conditions

Conditions	Yield
With sodium bromate; sulfuric acid; sodium bromide In water at 20℃; for 24h;	99%
With [bis(2-methylallyl)cycloocta-1,5-diene]ruthenium(II); (2-((2-(diphenylphosphanyl)ethyl)(quinolin-2-ylmethyl)amino)ethyl)diphenylphosphine oxide; potassium tert-butylate In n-heptane at 100℃; for 16h;	86%

57-10-3

1-hexadecylcarboxylic acid

A

36653-82-4

1-Hexadecanol

B

540-10-3

cetyl palmitate

Conditions

Conditions	Yield
With trimethylamine borane In xylene for 9h; Heating;	A 22% B 61%
With hydrogen; zirconium(IV) oxide In dodecane at 20 - 260℃; under 9000.9 Torr; Kinetics; Autoclave;

57-10-3

1-hexadecylcarboxylic acid

540-10-3

cetyl palmitate

Conditions

Conditions	Yield
With hydrogen In neat (no solvent) at 20 - 200℃; under 6000.6 Torr; for 24h; Autoclave; High pressure;	55%
With copper chromite; hydrogen at 360℃;

544-77-4

1-iodohexadecane

3508-01-8

silver palmitate

540-10-3

cetyl palmitate

36653-82-4

1-Hexadecanol

112-67-4

n-hexadecanoyl chloride

540-10-3

cetyl palmitate

Conditions

Conditions	Yield
With quinoline; chloroform anfangs unter Kuehlung, dann bei Zimmertemperatur;
With diethyl ether; magnesium
With pyridine
In pyridine; chloroform

112-67-4

n-hexadecanoyl chloride

catyl alcohol

catyl alcohol

540-10-3

cetyl palmitate

Conditions

Conditions	Yield
at 180℃;

36653-82-4

1-Hexadecanol

544-63-8

n-tetradecanoic acid

57-10-3

1-hexadecylcarboxylic acid

A

2599-01-1

tetradecanoic acid hexadecyl ester

B

540-10-3

cetyl palmitate

Conditions

Conditions	Yield
With phosphoric acid In hexane; water for 8.5h; Product distribution / selectivity; Heating / reflux;
With phosphoric acid In n-heptane; water for 18h; Product distribution / selectivity; Heating / reflux;
With phosphoric acid In water; toluene at 92℃; for 38.5h; Product distribution / selectivity; Heating / reflux;
With phosphoric acid In water; xylene at 105℃; for 1h; Product distribution / selectivity;
With phosphoric acid In water at 95℃; for 0.5h; Product distribution / selectivity;

...Expand

57-10-3

1-hexadecylcarboxylic acid

A

629-62-9

pentadecane

B

544-76-3

Hexadecane

C

36653-82-4

1-Hexadecanol

D

540-10-3

cetyl palmitate

Conditions

Conditions	Yield
With hydrogen In dodecane at 20 - 260℃; under 9000.9 Torr; Kinetics; Autoclave;

...Expand

57-10-3

1-hexadecylcarboxylic acid

A

629-62-9

pentadecane

B

36653-82-4

1-Hexadecanol

C

540-10-3

cetyl palmitate

Conditions

Conditions	Yield
With hydrogen In dodecane at 20 - 260℃; under 9000.9 Torr; Kinetics; Autoclave;
With hydrogen In dodecane at 280℃; under 39003.9 Torr; for 6h; Catalytic behavior; Kinetics; Time;

...Expand

112-39-0

hexadecanoic acid methyl ester

A

36653-82-4

1-Hexadecanol

B

629-80-1

n-hexadecylaldehyde

C

502-73-8

palmitone

D

540-10-3

cetyl palmitate

E

57-10-3

1-hexadecylcarboxylic acid

Conditions

Conditions	Yield
With hydrogen; zirconium(IV) oxide at 700℃; under 60006 Torr; Kinetics; Reagent/catalyst; Temperature; Pressure; Calcination;

...Expand

112-39-0

hexadecanoic acid methyl ester

A

629-62-9

pentadecane

B

34557-54-5

methane

C

544-76-3

Hexadecane

D

14852-31-4

hexadecan-2-ol

E

36653-82-4

1-Hexadecanol

F

629-80-1

n-hexadecylaldehyde

G

540-10-3

cetyl palmitate

H

124-38-9

carbon dioxide

I

201230-82-2

carbon monoxide

J

57-10-3

1-hexadecylcarboxylic acid

Conditions

Conditions	Yield
With hydrogen In dodecane at 290℃; under 22502.3 Torr;

...Expand

112-39-0

hexadecanoic acid methyl ester

A

629-62-9

pentadecane

B

34557-54-5

methane

C

544-76-3

Hexadecane

D

14852-31-4

hexadecan-2-ol

E

36653-82-4

1-Hexadecanol

F

629-80-1

n-hexadecylaldehyde

G

540-10-3

cetyl palmitate

H

201230-82-2

carbon monoxide

I

57-10-3

1-hexadecylcarboxylic acid

Conditions

Conditions	Yield
With hydrogen In dodecane at 290℃; under 22502.3 Torr;

...Expand

57-10-3

1-hexadecylcarboxylic acid

A

629-62-9

pentadecane

B

544-76-3

Hexadecane

C

36653-82-4

1-Hexadecanol

D

629-80-1

n-hexadecylaldehyde

E

540-10-3

cetyl palmitate

Conditions

Conditions	Yield
With hydrogen In dodecane at 280℃; under 39003.9 Torr; for 6h; Kinetics;

...Expand

57-10-3

1-hexadecylcarboxylic acid

A

544-76-3

Hexadecane

B

36653-82-4

1-Hexadecanol

C

629-80-1

n-hexadecylaldehyde

D

540-10-3

cetyl palmitate

Conditions

Conditions	Yield
With hydrogen In dodecane at 280℃; under 39003.9 Torr; for 6h; Kinetics;

...Expand

540-10-3

cetyl palmitate

O-hexadecyl hexadecanethiono ester

Conditions

Conditions	Yield
With Lawessons reagent In 5,5-dimethyl-1,3-cyclohexadiene Reflux;	58%

540-10-3

cetyl palmitate

629-80-1

n-hexadecylaldehyde

Conditions

Conditions	Yield
With dimethylsulfide borane complex; pyridinium chlorochromate 1) THF, reflux, 1 h, 2.) CH2Cl2, reflux, 1 h; Yield given. Multistep reaction;

540-10-3

cetyl palmitate

<1-14C>n-hexadecanol palmitate

<1-14C>n-hexadecanol palmitate

Conditions

Conditions	Yield
With 1-(14)C cetyl alcohol In acetone at 40℃; for 1h; transesterification with enzyme from Sinapis alba L.;

540-10-3

cetyl palmitate

<4-14C>cholesteryl palmitate

<4-14C>cholesteryl palmitate

Conditions

Conditions	Yield
With [14C]-Cholesterol In acetone at 40℃; for 1h; transesterification with enzyme from Sinapis alba L.; influence of incubation time and <1-14C>n-hexadecanol concentration on ester formation; double pH optima: 6.4, 8.4;

540-10-3

cetyl palmitate

α-particle/s

α-particle/s

A

hydrogen

hydrogen

B

carbon oxides

carbon oxides

C

hydrocarbons

hydrocarbons

Conditions

Conditions	Yield
Irradiation;

...Expand

monoglyceryl stearate

540-10-3

cetyl palmitate

A

monocetylphosphoric ester potassium salt

B

79-10-7

acrylic acid

...Expand

Cetyl palmitate Chemical Properties

Cetyl palmitate Toxicity Data With Reference

Cetyl palmitate Consensus Reports

Cetyl palmitate Safety Profile