Product Name: Codeine sulfate
Synonyms of Codeine sulfate (CAS NO.1420-53-7) : (5alpha,6alpha)-3-Methoxy-17-methyl-7,8-didehydro-4,5-epoxymorphinan-6-ol sulfate (1:1) ; Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5alpha,6alpha)-, sulfate (1:1) (salt) ; Codeine sulphate ; Copavin
CAS NO:1420-53-7
Molecular Formula:C18H23NO7S
Molecular Weight :397.4427
Molecular Structure :
Flash Point: 233.2 °C
Enthalpy of Vaporization: 76.18 kJ/mol
Boiling Point: 462 °C at 760 mmHg
Vapour Pressure: 2.47E-09 mmHg at 25°C
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 143mg/kg (143mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Journal of Pharmaceutical Sciences. Vol. 63, Pg. 451, 1974. |
mouse | LD50 | intravenous | 68mg/kg (68mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 134, Pg. 332, 1961. | |
mouse | LD50 | oral | 395mg/kg (395mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 134, Pg. 332, 1961. | |
mouse | LD50 | subcutaneous | 183mg/kg (183mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 134, Pg. 332, 1961. | |
rat | LD50 | intraperitoneal | 107mg/kg (107mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT BEHAVIORAL: REGIDITY | Toxicology. Vol. 14, Pg. 217, 1979. |
rat | LD50 | intravenous | 55mg/kg (55mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 134, Pg. 332, 1961. | |
rat | LD50 | oral | 430mg/kg (430mg/kg) | BEHAVIORAL: ANALGESIA | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 123, Pg. 48, 1959. |
rat | LD50 | subcutaneous | 332mg/kg (332mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 134, Pg. 332, 1961. |
Poison by ingestion, intraperitoneal, intravenous, and subcutaneous routes. An experimental teratogen. Other experimental reproductive effects. Mutation data reported. An addictive, narcotic drug. When Codeine sulfate (CAS NO.1420-53-7) is heated to decomposition it emits very toxic fumes of NOx and SOx. See also CODEINE.
Hazard Codes Xn
Risk Statements 22
R22: Codeine sulfate (CAS NO.1420-53-7) is harmful if swallowed.
RTECS QD1400000
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