Cyclandelate supplier | CasNO.456-59-7

Name
CYCLANDELATE
EINECS 207-271-6
CAS No. 456-59-7
Article Data9
CAS DataBase
Density 1.085 g/cm³
Solubility Insoluble in water
Melting Point 55.0-56.5°
Formula C₁₇H₂₄O₃
Boiling Point 380.1 °C at 760 mmHg
Molecular Weight 276.376
Flash Point 150.1 °C
Transport Information
Appearance
Safety
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms Mandelicacid, 3,3,5-trimethylcyclohexyl ester (6CI,7CI,8CI);Cyclohexanol,3,3,5-trimethyl-, mandelate (8CI);3,5,5-Trimethylcyclohexanol, mandelic acidester;Arto-Espasmol;Clandilon;Cyclobral;Natil;Spasmocyclon;
PSA 46.53000
LogP 3.47800

Cyclandelate Chemical Properties

Product Name: Cyclandelate (CAS NO.456-59-7)

Molecular Formula: C₁₇H₂₄O₃
Molecular Weight: 276.37g/mol
Mol File: 456-59-7.mol
Einecs: 207-271-6
Boiling point: 380.1 °C at 760 mmHg
Flash Point: 150.1 °C
Density: 1.08 g/cm³
Surface Tension: 41.8 dyne/cm
Enthalpy of Vaporization: 66.27 kJ/mol
Vapour Pressure: 1.86E-06 mmHg at 25°C
XLogP3-AA: 4.2
H-Bond Donor: 1
H-Bond Acceptor: 3
Product Categories: Cosmetic Ingredients and Chemicals

Cyclandelate Uses

Cyclandelate (CAS NO.456-59-7) is suitable in the treatment of cerebral arteriosclerosis, brain haggard in traumatic brain injury, venous thrombosis.

Cyclandelate Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intraperitoneal	2gm/kg (2000mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 105, Pg. 145, 1956.
guinea pig	LD50	intraperitoneal	2480mg/kg (2480mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 105, Pg. 145, 1956.
guinea pig	LD50	oral	3950mg/kg (3950mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: ATAXIA	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 105, Pg. 145, 1956.
mouse	LD50	intraperitoneal	3780mg/kg (3780mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 105, Pg. 145, 1956.
mouse	LD50	oral	> 10gm/kg (10000mg/kg)		Drugs in Japan Vol. 6, Pg. 310, 1982.
rat	LD50	intraperitoneal	2570mg/kg (2570mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 105, Pg. 145, 1956.
rat	LD50	oral	5gm/kg (5000mg/kg)		Drugs in Japan Vol. 6, Pg. 310, 1982.

Cyclandelate Consensus Reports

Reported in EPA TSCA Inventory.

Cyclandelate Safety Profile

Moderately toxic by ingestion and intraperitoneal routes. When heated to decomposition it emits acrid smoke and fumes. See also ESTERS.

Cyclandelate Specification

Cyclandelate ,its CAS NO. is 456-59-7,the synonyms is 3,3,5-Trimethylcyclohexanol alpha-phenyl-alpha-hydroxyacetate ; 3,3,5-Trimethylcyclohexanolalpha-phenyl-alpha-hydroxyacetate ; 3,3,5-Trimethylcyclohexyl hydroxy(phenyl)acetate ; 3,5,5-Trimethylcyclohexanol,mandelicacidester ; 3,5,5-Trimethylcyclohexyl amygdalate ; 3,5,5-Trimethylcyclohexylamygdalate ; 3,5,5-Trimethylcyclohexylmandelate ; Alpha-Hydroxybenzeneacetic acid 3,3,5-trimethylcyclohexyl ester .

Product Name

CYCLANDELATE