Product Name: Delapril hydrochloride (CAS NO.83435-67-0)
Molecular Formula: C26H32N2O5.HCl
Molecular Weight: 489.0036 g/mol
Mol File: 83435-67-0.mol
Appearance: White crystalline powder
Boiling point: 659.7 °C at 760 mmHg
Flash Point: 352.7 °C
Enthalpy of Vaporization: 102 kJ/mol
Vapour Pressure: 2.67E-18 mmHg at 25°C
H-Bond Donor: 3
H-Bond Acceptor: 6
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 164mg/kg (164mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 15(Suppl, |
mouse | LD50 | oral | 3120mg/kg (3120mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 15(Suppl, |
mouse | LD50 | subcutaneous | 2340mg/kg (2340mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 15(Suppl, |
rat | LD50 | intraperitoneal | 208mg/kg (208mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 15(Suppl, |
rat | LD50 | oral | 8260mg/kg (8260mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 15(Suppl, |
rat | LD50 | subcutaneous | 5900mg/kg (5900mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 15(Suppl, |
Poison by intraperitoneal route. Moderately toxic by ingestion and subcutaneous routes. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and HCl.
Delapril hydrochloride ,its CAS NO. is 83435-67-0,the synonyms is Delapril hcl ; Delapril hydrochloride ; Dalapril hcl ; n-(n-((s)-1-Ethoxycarbonyl-3-phenylpropyl)-l-alanyl)-n-(indan-2-yl)gly cine hydrochloride ; Adecut ; Cupressin ; Cv 3317 ; Glycine, n-(2,3-dihydro-1h-inden-2-yl)-n-[n-[1-(ethoxycarbonyl)-3-phenylpropyl]-l-alanyl]-, monohydrochloride, (s)- .
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