Product Name

  • Name

    alpha-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide

  • EINECS 200-105-3
  • CAS No. 51-56-9
  • Density 1.21g/cm3
  • Solubility Soluble in water
  • Melting Point 214-217 ºC
  • Formula C16H21 N O3 . Br H
  • Boiling Point 434.9 °C at 760 mmHg
  • Molecular Weight 356.26
  • Flash Point 216.8 °C
  • Transport Information
  • Appearance Colorless or white powder. Bromine-like odor.
  • Safety Poison by intravenous and intraperitoneal routes. When heated to decomposition it emits toxic vapors of NOx and Br.
  • Risk Codes R23/24/25   
  • Molecular Structure Molecular Structure of 51-56-9 (alpha-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide)
  • Hazard Symbols
  • Synonyms 1aH,5aH-Tropan-3a-ol, mandelate (ester), hydrobromide (8CI); Benzeneacetic acid, a-hydroxy-,(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide (9CI);Benzeneacetic acid, a-hydroxy-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide,endo-; (?à)-Homatropine bromide;Homatropine bromide; Homatropine hydrobromide; Isopto Homatropine; Mandelicacid tropine ester hydrobromide
  • PSA 49.77000
  • LogP 2.78440

DL-Homatropine hydrobromide Chemical Properties

Product Name: alpha-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide
The MF of alpha-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide (51-56-9) is C16H22BrNO3.

                               
The MW of alpha-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide (51-56-9) is 356.25.
Synonyms: alpha-hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide ; MANDELYTROPINE HYDROBROMIDE ; (+/-)-HOMATROPINE HYDROBROMIDE ; HOMATROPINE HYDROBROMIDE ; DL-HOMATROPINE HYDROBROMIDE ; (+-)-homatropinebromide ; 1-alpha-h,5-alpha-h-tropan-3-alpha-ol,mandelate(ester),hydrobromide ; alpha-hydroxy-benzeneaceticaci8-methyl-8-azabicyclo(3.2.1)oct-3-yleste
Product Categories: Miscellaneous Natural Products;Alkaloids;Biochemistry;Tropane Alkaloids;Acetylcholine receptor
EINECS: 200-105-3
Form: white crystals or crystalline powder
Flash Point: 197.7 °C 
Boiling Point: 403.3 °C at 760 mmHg 
Melting Point: 214-217 °C 
Water Solubility: soluble
Merck: 4730

DL-Homatropine hydrobromide Uses

   Alpha-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide (51-56-9) is given as eye drops to dilate the pupil and relax the lens so that eye examinations can be carried out thoroughly.
 

DL-Homatropine hydrobromide Toxicity Data With Reference

1.    

ipr-rat LD50:154 mg/kg

    DRUGAY    Drugs. International Journal of Current Therapeutics and Applied Pharmacology Reviews. 6 (1982),789.
2.    

ivn-mus LD50:107 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 96 (1949),1.

DL-Homatropine hydrobromide Consensus Reports

Reported in EPA TSCA Inventory.

DL-Homatropine hydrobromide Safety Profile

Poison by intravenous and intraperitoneal routes. When heated to decomposition it emits toxic vapors of NOx and Br.
Safety information of alpha-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide (51-56-9):
Hazard Codes  T
Risk Statements  23/24/25
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed 
Safety Statements  45-24/25-22
S45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
S24/25: Avoid contact with skin and eyes
S22: Do not breathe dust
RIDADR  1544
RTECS  YM5602000

DL-Homatropine hydrobromide Specification

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

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