-
Name
DEXCHLORPHENIRAMINE MALEATE
- EINECS 219-450-6
- CAS No. 2438-32-6
- Article Data7
- CAS DataBase
- Density
- Solubility
- Melting Point 112-115 °C(lit.)
- Formula C16H19ClN2•C4H4O4
- Boiling Point 379 °C at 760 mmHg
- Molecular Weight 390.867
- Flash Point 183 °C
- Transport Information UN 2811 6.1/PG 3
- Appearance White solid
- Safety 36/37/39-45
- Risk Codes 25
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Molecular Structure
-
Hazard Symbols
T
- Synonyms (+)-2-(p-Chloro-alpha-(2-(dimethylamino)ethyl)benzyl)pyridine maleate (1:1);D-Chlorpheniramine maleate;Polaramine (TN);(+)-Chlorpheniramine maleate;Polaramine;(gamma-(4-Chlorophenyl)-pyridine-2-propyl)(dimethyl)ammonium hydrogen (Z)-maleate;but-2-enedioic acid; (3S)-3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-yl-propan-1-amine;Pyridine, 2-(p-chloro-alpha-(2-(dimethylamino)ethyl)benzyl)-, maleate (1:1), (+)-;S-(+)-Chlorpheniramine maleate;
- PSA 90.73000
- LogP 3.53040
Dexchloropheniramine maleate Chemical Properties
MF: C20H23ClN2O4
MW: 390.86
EINECS: 204-037-5
Flash Point: 183 °C
Melting Point: 112-115 °C(lit.)
Enthalpy of Vaporization: 62.7 kJ/mol
Vapour Pressure: 6.04E-06 mmHg at 25°C
Boiling Point of Polaramine maleate (2438-32-6): 379 °C at 760 mmHg
IUPAC Nsme: (Z)-but-2-enedioic acid ; (3S)-3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine
Synonyms: (+)-Chlorpheniramine maleate salt ; Dexchloropheniramine maleate ; Dexchlorpheniramine maleate ; D-chlorpheniramine maleate ; Gamma-[4-chlorophenyl]-N,N-dimethyl-2-pyridinepropanamine maleate salt ; (+)-2-(P-chloro-alpha-(2-(dimethylamino)ethyl)benzyl)pyridinemaleate ; (S)-(+)-Chlorpheniraminemaleate ; Dextrochlorpheniraminemaleate
Following is the molecular structure of Polaramine maleate (2438-32-6):
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Dexchloropheniramine maleate Uses
Polaramine maleate (2438-32-6) is a cholinergic drugs treating simple conjunctivitis. Preparations for the drops.
Dexchloropheniramine maleate Toxicity Data With Reference
| 1. | orl-rat LD50:267 mg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 124 (1958),347. | ||
| 2. | ipr-rat LD50:119 mg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 124 (1958),347. | ||
| 3. | orl-mus LD50:189 mg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 124 (1958),347. | ||
| 4. | ipr-mus LD50:117 mg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 124 (1958),347. | ||
| 5. | ivn-mus LD50:28 mg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 124 (1958),347. | ||
| 6. | orl-gpg LD50:240 mg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 124 (1958),347. |
Dexchloropheniramine maleate Safety Profile
Poison by ingestion, intravenous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of Cl− and NOx.
Safety Information of Polaramine maleate (2438-32-6):
Hazard Codes: T
T: Toxic .gif)
Risk Statements: 25
25: Toxic if swallowed
Safety Statements: 36/37/39-45
36/37/39: Wear suitable protective clothing, gloves and eye/face protection
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: US6504000
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