Product Name

  • Name

    (S)-3-phenyl-1'-(phenylmethyl)[3,4'-bipiperidine]-2,6-dione monohydrochloride

  • EINECS
  • CAS No. 21888-96-0
  • Density g/cm3
  • Solubility
  • Melting Point 270-275°
  • Formula C23H26 N2 O2 . Cl H
  • Boiling Point 543.9°Cat760mmHg
  • Molecular Weight 398.97
  • Flash Point 282.7°C
  • Transport Information
  • Appearance
  • Safety Poison by intravenous route. An anticholinergic agent used to treat Parkinson's disease. When heated to decomposition it emits very toxic fumes of HCl and NOx.
  • Risk Codes
  • Molecular Structure Molecular Structure of 21888-96-0 ((S)-3-phenyl-1'-(phenylmethyl)[3,4'-bipiperidine]-2,6-dione monohydrochloride)
  • Hazard Symbols
  • Synonyms Glutarimide,2-(1-benzyl-4-piperidyl)-2-phenyl-, monohydrochloride, (S)-(+)- (8CI);[3,4'-Bipiperidine]-2,6-dione, 3-phenyl-1'-(phenylmethyl)-, monohydrochloride,(S)-; (+)-Benzetimide hydrochloride; (S)-(+)-Dexetimide hydrochloride;Dexetimide hydrochloride; Dextrobenzetimide; R 16470; Tremblex
  • PSA 49.41000
  • LogP 4.34190

Dextrobenzetimide hydrochloride Chemical Properties

Molecule structure of Dextrobenzetimide hydrochloride (CAS NO.21888-96-0):

IUPAC Name: (3S)-3-(1-Benzylpiperidin-1-ium-4-yl)-3-phenylpiperidine-2,6-dione chloride 
Molecular Weight: 398.92568 g/mol
Molecular Formula: C23H27ClN2O2 
Boiling Point: 543.9 °C at 760 mmHg
Flash Point: 282.7 °C
Enthalpy of Vaporization: 82.24 kJ/mol
Vapour Pressure: 6.86E-12 mmHg at 25 °C
H-Bond Donor: 2
H-Bond Acceptor: 3
Rotatable Bond Count: 4
Tautomer Count: 5
Exact Mass: 398.176106
MonoIsotopic Mass: 398.176106
Topological Polar Surface Area: 50.6
Heavy Atom Count: 28
Complexity: 529
Defined Atom StereoCenter Count: 1
Canonical SMILES: C1C[NH+](CCC1C2(CCC(=O)NC2=O)C3=CC=CC=C3)CC4=CC=CC=C4.[Cl-]
Isomeric SMILES: C1C[NH+](CCC1[C@@]2(CCC(=O)NC2=O)C3=CC=CC=C3)CC4=CC=CC=C4.[Cl-]
InChI: InChI=1S/C23H26N2O2.ClH/c26-21-11-14-23(22(27)24-21,19-9-5-2-6-10-19)20-12-15-25(16-13-20)17-18-7-3-1-4-8-18;/h1-10,20H,11-17H2,(H,24,26,27);1H/t23-;/m1./s1
InChIKey: XSOOSXRNMDUWEM-GNAFDRTKSA-N
EINECS: 244-633-2 
Classification Code of Dextrobenzetimide hydrochloride (CAS NO.21888-96-0): Anticholinergic; Drug / Therapeutic Agent

Dextrobenzetimide hydrochloride Toxicity Data With Reference

1.    

ivn-rat LD50:45 mg/kg

     27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,219.
2.    

ivn-mus LD50:45 mg/kg

     ARZNAD    Arzneimittel-Forschung. Drug Research. 21 (1971),1365.

Dextrobenzetimide hydrochloride Safety Profile

Poison by intravenous route. An anticholinergic agent used to treat Parkinson's disease. When heated to decomposition it emits very toxic fumes of HCl and NOx.

Dextrobenzetimide hydrochloride Specification

 Dextrobenzetimide hydrochloride (CAS NO.21888-96-0) is also named as (+)-1-Benzyl-4-(2,6-dioxo-3-phenyl-3-piperidyl)piperidine hydrochloride ; (+)-2-(1-Benzyl-4-piperidyl)-2-phenylglutarimide hydrochloride ; (+)-3-(1-Benzyl-4-piperidyl)-3-phenylpiperidine-2,6-dione hydrochloride ; (S)-3-Phenyl-1'-(phenylmethyl)-(3,4'-bipiperidine)-2,6-dione hydrochloride ; Dexbenzetimide hydrochloride ; Dexetimide HCl ; Dexetimide hydrochloride ; R 16470 ; Tremblex .

Related Products

Hot Products

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View