Product Name

  • Name

    Glisolamide

  • EINECS
  • CAS No. 24477-37-0
  • Density 1.35g/cm3
  • Solubility
  • Melting Point 198°C
  • Formula C20H26 N4 O5 S
  • Boiling Point °Cat760mmHg
  • Molecular Weight 434.516
  • Flash Point °C
  • Transport Information
  • Appearance
  • Safety Poison by intraperitoneal route. Moderately toxic by subcutaneous route. An experimental teratogen. When heated to decomposition it emits toxic fumes of SOx and NOx.
  • Risk Codes
  • Molecular Structure Molecular Structure of 24477-37-0 (Glisolamide)
  • Hazard Symbols
  • Synonyms Urea,1-cyclohexyl-3-[[p-[2-(5-methyl-3-isoxazolecarboxamido)ethyl]phenyl]sulfonyl]-(8CI); Diabenor; Glisolamide; Glysolamide
  • PSA 138.78000
  • LogP 4.52960

Diabenor Chemical Properties

Product Name: Diabenor (CAS NO.24477-37-0)


Molecular Formula: C20H26N4O5S
Molecular Weight: 434.56g/mol
Mol File: 24477-37-0.mol
Density: 1.35 g/cm3
Surface Tension: 63.8 dyne/cm
XLogP3-AA: 3.3
H-Bond Donor: 3
H-Bond Acceptor: 6
Structure Descriptors of Diabenor (CAS NO.24477-37-0):
  IUPAC Name: N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-5-methyl-1,2-oxazole-3-carboxamide
  Canonical SMILES: CC1=CC(=NO1)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3
  InChI: InChI=1S/C20H26N4O5S/c1-14-13-18(23-29-14)19(25)21-12-11-15-7-9-17(10-8-15)30(27,28)24-20(26)22-16-5-3-2-4-6-16/h7-10,13,16H,2-6,11-12H2,1H3,(H,21,25)(H2,22,24,26) 
  InChIKey: GZKDXUIWCNCNBJ-UHFFFAOYSA-N

Diabenor Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 230mg/kg (230mg/kg)   Bollettino Chimico Farmaceutico. Vol. 117, Pg. 348, 1978.
mouse LD50 oral > 3gm/kg (3000mg/kg)   Bollettino Chimico Farmaceutico. Vol. 117, Pg. 348, 1978.
mouse LD50 subcutaneous 720mg/kg (720mg/kg)   Bollettino Chimico Farmaceutico. Vol. 117, Pg. 348, 1978.
rat LD50 intraperitoneal 320mg/kg (320mg/kg)   Bollettino Chimico Farmaceutico. Vol. 117, Pg. 348, 1978.
rat LD50 oral > 3gm/kg (3000mg/kg)   Bollettino Chimico Farmaceutico. Vol. 117, Pg. 348, 1978.
rat LD50 subcutaneous 900mg/kg (900mg/kg)   Bollettino Chimico Farmaceutico. Vol. 117, Pg. 348, 1978.

Diabenor Safety Profile

Poison by intraperitoneal route. Moderately toxic by subcutaneous route. An experimental teratogen. When heated to decomposition it emits toxic fumes of SOx and NOx.

Diabenor Specification

 Diabenor ,its CAS NO. is 24477-37-0,the synonyms is 1-Cyclohexyl-3-((p-(2-(5-methyl-3-isoxazolecarboxamido)ethyl)phenyl)sulfonyl)urea ; BRN 1050609 ; Glisolamida  ; Glysolamide ; N-(2-(4-((((Cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-5-methyl-3-isoxazolecarboxamide ; N-(4-(beta-(5-Metilossazol-3-carbossamido)-etil)-benzenesolfonil)-N(sup 1)-cicloesil-urea ; P.M. 434,526 ; UNII-F83U6T74XR ; 3-Isozazolecarboxamide, N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-5-methyl- ; Urea, 1-cyclohexyl-3-((p-(2-(5-methyl-3-isoxazolecarboxamido)ethyl)phenyl)sulfonyl)- .

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