Diltiazem

IUPAC Name: [(2S,3S)-5-(2-dimethylaminoethyl)-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate 
Empirical Formula: C₂₂H₂₆N₂O₄S
Molecular Weight: 414.5178g/mol
 EINECS: 255-796-4
Structure of Diltiazem (CAS NO.42399-41-7):

Index of Refraction: 1.62
Molar Refractivity: 115.15 cm³
Molar Volume: 327.6 cm³
Polarizability: 45.65×10^-24cm³
Surface Tension: 56.2 dyne/cm
Density: 1.26 g/cm³
Flash Point: 313.3 °C
Enthalpy of Vaporization: 88.6 kJ/mol
Boiling Point: 594.4 °C at 760 mmHg
Vapour Pressure: 4.27E-14 mmHg at 25°C 
Classification Code :Antihypertensive agents, Calcium channel blockers, Cardiovascular agents, Drug / Therapeutic Agent, Membrane Transport Modulators, Vasodilator agents 
Canonical SMILES: CC(=O)OC1C(SC2=CC=CC=C2N(C1=O)CCN(C)C)C3=CC=C(C=C3)OC
Isomeric SMILES: CC(=O)O[C@@H]1[C@@H](SC2=CC=CC=C2N(C1=O)CCN(C)C)C3=CC=C(C=C3)OC
InChI: InChI=1S/C22H26N2O4S/c1-15(25)28-20-21(16-9-11-17(27-4)12-10-16)29-19-8-6-5-7-18(19)24(22(20)26)14-13-23(2)3/h5-12,20-21H,13-14H2,1-4H3/t20-,21+/m1/s1
InChIKey: HSUGRBWQSSZJOP-RTWAWAEBSA-N

  Diltiazem (CAS NO.42399-41-7) is a non-dihydropyridine (DHP) member of the group of drugs known as benzothiazepines, which are a class of calcium channel blockers, used in the treatment of hypertension, angina pectoris, and some types of arrhythmia. It is also an effective preventive medication for migraine. It is a class 3 anti-anginal drug, and a class IV antiarrhythmic. It is a common adulterant of cocaine seized in the UK , despite reducing cocaine cravings in rats (see below). It incites very minimal reflex sympathetic changes.

  Diltiazem , its cas register number is 42399-41-7. It also can be called Acalix ; Adizem ; Anoheal ; BRN 3573079 ; CRD-401 ; Cardil ; Cardizem ; Cardizem LA ; Dilacor XR ; Dilcontin ; Dilren ; Dilta-Hexal ; Diltiazem ; Diltiazemum ; Dilticard ; Dilzen  ; Endrydil ; HSDB 6528 ; Incoril AP ; UNII-EE92BBP03H ; d-cis-Diltiazem .