DIMETHYL PYRAZOLO[1,5-A]PYRIDINE-2,3-DICARBOXYLATE

This chemical is called Dimethyl pyrazolo[1,5-a]pyridine-2,3-dicarboxylate, and it can also be named as Pyrazolo[1,5-a]pyridine-2,3-dicarboxylicacid, 2,3-dimethyl ester. With the molecular formula of C₁₁H₁₀N₂O₄, its molecular weight is 234.21. The CAS registry number of this chemical is 5825-71-8.

Other characteristics of the Dimethyl pyrazolo[1,5-a]pyridine-2,3-dicarboxylate can be summarised as followings: (1)ACD/LogP: 1.10; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.1; (4)ACD/LogD (pH 7.4): 1.1; (5)ACD/BCF (pH 5.5): 4.01; (6)ACD/BCF (pH 7.4): 4.01; (7)ACD/KOC (pH 5.5): 94.02; (8)ACD/KOC (pH 7.4): 94.02; (9)#H bond acceptors: 6; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 4; (12)Polar Surface Area: 69.9 Å²; (13)Index of Refraction: 1.596; (14)Molar Refractivity: 59.26 cm³; (15)Molar Volume: 174 cm³; (16)Polarizability: 23.49×10^-24cm³; (17)Surface Tension: 47.9 dyne/cm; (18)Density: 1.34 g/cm³.

Production method of this chemical: The Dimethyl pyrazolo[1,5-a]pyridine-2,3-dicarboxylate could be obtained by the reactants of butynedioic acid dimethyl ester and 1-amino-pyridinium; iodide. This reaction needs the reagent of K₂CO₃, air-O₂, and the solvent of dimethylformamide. The yield is 45 %. In addition, this reaction should be taken for 2 hours at the temperature of 20 °C.

Uses of this chemical: The 2-hydrazinocarbonyl-pyrazolo[1,5-a]pyridine-3-carboxylic acid methyl ester could be obtained by the reactant of Dimethyl pyrazolo[1,5-a]pyridine-2,3-dicarboxylate. This reaction needs the reagent of anhydrous hydrazine, and the solvent of ethanol. The yield is 89 %. This reaction should be taken for 4 hours at the ambient temperature.

You can still convert the following datas into molecular structure: 
1.SMILES: O=C(OC)c1nn2c(c1C(=O)OC)cccc2
2.InChI: InChI=1/C11H10N2O4/c1-16-10(14)8-7-5-3-4-6-13(7)12-9(8)11(15)17-2/h3-6H,1-2H3 
3.InChIKey: NZJIUQJPKXRRHB-UHFFFAOYAF