Product Name

  • Name

    DIPHENAMID

  • EINECS 213-482-4
  • CAS No. 957-51-7
  • Article Data32
  • CAS DataBase
  • Density 1.07 g/cm3
  • Solubility -2.98 in water
  • Melting Point 132-136 ºC
  • Formula C16H17 N O
  • Boiling Point 382.4 ºC
  • Molecular Weight 239.317
  • Flash Point 173.3 ºC
  • Transport Information
  • Appearance white or off-white powder
  • Safety Moderately toxic by ingestion, intraperitoneal, and subcutaneous routes. Mutation data reported. A pesticide. When heated to decomposition it emits toxic fumes of NOx.
  • Risk Codes R22;R52/53   
  • Molecular Structure Molecular Structure of 957-51-7 (DIPHENAMID)
  • Hazard Symbols
  • Synonyms Acetamide,N,N-dimethyl-2,2-diphenyl- (8CI); Diphenamide (6CI,7CI); Dif 4; Diherbid;Dimid; Diphenamid; Diphenylacetic acid dimethylamide; Dymid; Enide; Enide 50;Enide 50W; Fenam; L 34314; Lilly 34,314; N,N-Dimethyl-2,2-diphenylacetamide;N,N-Dimethyl-a,a-diphenylacetamide;N,N-Dimethyldiphenylacetamide; Rideon; Zarur
  • PSA 20.31000
  • LogP 2.90670

Diphenamid Chemical Properties

Chemistry informtion about N,N-Dimethyl-2,2-Diphenylacetamide (CAS NO.957-51-7) is:
IUPAC Name: N,N-Dimethyl-2,2-Diphenylacetamide
Synonyms: 80w ; Acetamide, N,N-Dimethyl-2,2-Diphenyl- ; Benzeneacetamide,N,N-Dimethyl-Α-Phenyl- ; Dif 4 ; Dif4 ; Difenamid ; Difenamide ; Diherbid
MF: C16H17NO
MW: 239.31
EINECS: 213-482-4 
Density: 1.07 g/cm3
Melting Point: 132-136 °C(lit.) 
Flash Point: 173.3 °C
Boiling Point: 382.4 °C at 760 mmHg
Vapour Pressure: 4.75E-06 mmHg at 25°C
Enthalpy of Vaporization: 63.08 kJ/mol
Storage temp.: 0-6°C
Merck: 13,3339
Stability: Stable. Incompatible with strong oxidizing agents, strong bases. 
Following is the molecular structure of N,N-Dimethyl-2,2-Diphenylacetamide (CAS NO.957-51-7) is:

Diphenamid Uses

 N,N-Dimethyl-2,2-Diphenylacetamide (CAS NO.957-51-7) is used as an herbicide.

Diphenamid Production

Raw Materials are N,N-Dimethylformamide --> Thionyl Chloride --> Chloroform --> Hydrogen --> Methylamine --> Chloral --> 2-Ethoxyethanol --> Trichloroethane --> 2,2-Diphenylacetic Acid --> Diphenylacetyl Chloride

Diphenamid Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 oral 1gm/kg (1000mg/kg)   "Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969Vol. 5, Pg. 84, 1976.
mammal (species unspecified) LD50 unreported 700mg/kg (700mg/kg)   "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 155, 1971.
monkey LD50 oral 1gm/kg (1000mg/kg)   "Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969Vol. 5, Pg. 84, 1976.
mouse LD50 intraperitoneal 500mg/kg (500mg/kg)   Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 233, 1973.
mouse LD50 oral 600mg/kg (600mg/kg)   Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 431, 1966.
mouse LD50 subcutaneous 800mg/kg (800mg/kg)   Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 233, 1973.
mouse LD50 unreported 700mg/kg (700mg/kg)   Tsitologiya i Genetika. Cytology and Genetics. For English translation, see CYGEDX. Vol. 16(1), Pg. 45, 1982.
rabbit LD50 oral 1500mg/kg (1500mg/kg)   "Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969Vol. 5, Pg. 84, 1976.
rat LD50 oral 685mg/kg (685mg/kg)   Journal of Drug Research. Vol. 12(1-2), Pg. 155, 1980.
rat LD50 skin > 6320mg/kg (6320mg/kg)   World Review of Pest Control. Vol. 9, Pg. 119, 1970.

Diphenamid Safety Profile

Moderately toxic by ingestion, intraperitoneal, and subcutaneous routes. Mutation data reported. A pesticide. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes:
HarmfulXn
Risk Statements:
R22:Harmful if swallowed. 
R52/53:Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements:
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
RTECS: AB8050000

Diphenamid Specification

 N,N-Dimethyl-2,2-Diphenylacetamide (CAS NO.957-51-7) is a colorless to off-white crystals. It is an amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx). Also it is decomposed by strong base or acid.

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