Product Name

  • Name

    Dipivefrin hydrochloride

  • EINECS 264-609-5
  • CAS No. 64019-93-8
  • Density
  • Solubility
  • Melting Point 158-159°
  • Formula C19H29 N O5 . Cl H
  • Boiling Point 473.7 °C at 760 mmHg
  • Molecular Weight 387.904
  • Flash Point 240.3 °C
  • Transport Information
  • Appearance
  • Safety Poison by ingestion, subcutaneous, intravenous and intraperitoneal routes. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and HCl.
  • Risk Codes
  • Molecular Structure Molecular Structure of 64019-93-8 (Dipivefrin hydrochloride)
  • Hazard Symbols
  • Synonyms Propanoicacid, 2,2-dimethyl-, 4-[1-hydroxy-2-(methylamino)ethyl]-1,2-phenylene ester,hydrochloride (9CI); Propanoic acid, 2,2-dimethyl-,4-[1-hydroxy-2-(methylamino)ethyl]-1,2-phenylene ester, hydrochloride, (?à)-; D Epifrin; Diopine; Diphemin;Dipivefrin hydrochloride; Dipivefrine hydrochloride; Pivalephrine; Propine
  • PSA 84.86000
  • LogP 4.03530

Dipivefrin hydrochloride Chemical Properties

Chemical Name: Dipivefrin hydrochloride
IUPAC NAME: [2-(2,2-dimethylpropanoyloxy)-5-[1-hydroxy-2-(methylamino)ethyl]phenyl] 2,2-dimethylpropanoate hydrochloride
CAS No.: 64019-93-8
EINECS: 264-609-5
Molecular Formula: C19H30ClNO5
Molecular Weight: 387.8982 g/mol
Flash Point: 240.3 °C
Boiling Point: 473.7 °C at 760 mmHg
Following is the structure of Dipivefrin hydrochloride (64019-93-8):


The chemical synonymous of Dipivefrin hydrochloride (64019-93-8) are Dipivalylepinephrinehydrochloride ; Dipivefrinehydrochloride ; Dipivefrinhydrochloride ; Hydrochloride,(+-)-Este ; Propanoicacid,2,2-dimethyl-,4-(1-hydroxy-2-(methylamino)ethyl)-1,2-phenylene ; Dipivefrin hydrochloride (200 Mg) ; (±)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-phenylene dipivalate hydrochloride ; Dipivaloyl epinephrine hydrochloride

Dipivefrin hydrochloride Toxicity Data With Reference

1.    

orl-rat LD50:183 mg/kg

     KSRNAM    Kiso to Rinsho. Clinical Report. 20 (1986),25.
2.    

ipr-rat LD50:8500 µg/kg

     KSRNAM    Kiso to Rinsho. Clinical Report. 20 (1986),25.
3.    

scu-rat LD50:21,200 µg/kg

     KSRNAM    Kiso to Rinsho. Clinical Report. 20 (1986),25.
4.    

orl-mus LD50:224 mg/kg

     KSRNAM    Kiso to Rinsho. Clinical Report. 20 (1986),25.
5.    

ipr-mus LD50:32,700 µg/kg

     KSRNAM    Kiso to Rinsho. Clinical Report. 20 (1986),25.
6.    

scu-mus LD50:35 mg/kg

     KSRNAM    Kiso to Rinsho. Clinical Report. 20 (1986),25.
7.    

ivn-mus LD50:4 mg/kg

     KSRNAM    Kiso to Rinsho. Clinical Report. 20 (1986),25.

Dipivefrin hydrochloride Safety Profile

Poison by ingestion, subcutaneous, intravenous and intraperitoneal routes. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and HCl.

Dipivefrin hydrochloride Specification

 Dipivefrin hydrochloride (64019-93-8) is a prodrug of adrenaline, which is used to treat glaucoma.It is available as ophthalmic solution .It causes vasoconstriction, decreased aqueous humor production, and decreases intraoccular pressure.It gets converted to epinephrine upon penetrating the cornea.

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