Molecule structure of Dominal (CAS NO.303-69-5) :
IUPAC Name: N,N-dimethyl-3-pyrido[3,2-b][1,4]benzothiazin-10-ylpropan-1-amine
Molecular Weight: 285.40716 g/mol
Molecular Formula: C16H19N3S
Density: 1.168 g/cm3
Melting Point: < 25 °C
Boiling Point: 430.8 °C at 760 mmHg
Flash Point: 214.3 °C
Index of Refraction: 1.621
Molar Refractivity: 85.95 cm3
Molar Volume: 244.1 cm3
Polarizability: 34.07*10-24 cm3
Surface Tension: 48.7 dyne/cm
Enthalpy of Vaporization: 68.63 kJ/mol
Vapour Pressure: 1.26E-07 mmHg at 25 °C
log P (octanol-water): 4.010
Atmospheric OH Rate Constant: 1.98E-10 cm3/molecule-sec
XLogP3-AA: 3.4
H-Bond Acceptor: 3
Rotatable Bond Count: 4
Exact Mass: 285.129968
MonoIsotopic Mass: 285.129968
Topological Polar Surface Area: 19.4
Heavy Atom Count: 20
Complexity: 310
Canonical SMILES: CN(C)CCCN1C2=CC=CC=C2SC3=C1N=CC=C3
InChI: InChI=1S/C16H19N3S/c1-18(2)11-6-12-19-13-7-3-4-8-14(13)20-15-9-5-10-17-16(15)19/h3-5,7-10H,6,11-12H2,1-2H3
InChIKey Dominal (CAS NO.303-69-5) : JTTAUPUMOLRVRA-UHFFFAOYSA-N
1. | ivn-rat LD50:25 mg/kg | THERAP Therapie. 18 (1963),373. | ||
2. | orl-mus LD50:415 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 8 (1958),489. | ||
3. | ipr-mus LD50:155 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 8 (1958),489. | ||
4. | scu-mus LD50:102 mg/kg | AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. 149 (1964),374. |
Poison by intravenous, subcutaneous, and intraperitoneal routes. Moderately toxic by ingestion. When heated to decomposition it emits very toxic fumes of SOx and NOx.
Dominal (CAS NO.303-69-5) is also called 10-(3-Dimethylaminopropyl)-1-azaphenothiazin ; 10-(3-Dimethylaminopropyl)-10H-pyrido(3,2-b)(1,4)benzothiazin ; 10H-Pyrido(3,2-b)(1,4)benzothiazine-10-propanamine, N,N-dimethyl- ; 4-27-00-07169 (Beilstein Handbook Reference) ; AY 56031 ; BRN 0259865 ; D 206 ; Dimethylamino-n-propyl-thiophenylpyridylamine ; Largophren ; MH 05101 ; Prothipendyl ; Prothipendylum [INN-Latin] ; Protipendilo [INN-Spanish] ; Timoval ; Timovan ; Tolnate ; Tumovan ; UNII-5O6VWA87VA .
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View