ETHAMBUTOL DIHYDROCHLORIDE Chemical Properties
IUPAC Name: (2S)-2-[2-[[(2S)-1-hydroxybutan-2-yl]amino]ethylamino]butan-1-ol
dihydrochloride
The MF of ETHAMBUTOL DIHYDROCHLORIDE(1070-11-7): C
10H
24N
2O
2·2(HCl)
The MW of ETHAMBUTOL DIHYDROCHLORIDE(1070-11-7): 277.23
EINECS: 213-970-7
Density: 0.987 g/cm
3 Flash Point: 113.7 °C
Boiling Point: 345.3 °C at 760 mmHg
Index of Refraction: 1.477
Synonyms: ETHAMBUTOL HCL; Ethambutol Hydrochloride; 2,2'-(1,2-Ethanediyldiimino)bis-1-butanol dihydrochloride; [S-(R*,R*)]-2,2'-(Ethylenediimino)dibutan-1-ol dihydrochloride
The Structure of ETHAMBUTOL DIHYDROCHLORIDE(1070-11-7):
ETHAMBUTOL DIHYDROCHLORIDE Uses
ETHAMBUTOL DIHYDROCHLORIDE(1070-11-7) is used as antibacterial.
ETHAMBUTOL DIHYDROCHLORIDE Toxicity Data With Reference
1. | | mnt-mus-orl 50 mg/kg | | IRLCDZ IRCS Medical Science: Library Compendium. 10 (1982),135. |
2. | | spm-mus-orl 12,500 µg/kg | | IRLCDZ IRCS Medical Science: Library Compendium. 10 (1982),135. |
3. | | orl-man TDLo:45 mg/kg/3D-I:EYE | | BJDCAT British Journal of Diseases of the Chest. 80 (1986),288. |
4. | | orl-man TDLo:46 mg/kg/3D-I:EYE | | PGMJAO Postgraduate Medical Journal. 61 (1985),811. |
5. | | unr-wmn TDLo:720 mg/kg/48D:EYE | | ANOPB5 Annals of Ophthalmology. 2 (1970),578. |
6. | | orl-rat LD50:6800 mg/kg | | OYYAA2 Oyo Yakuri. Pharmacometrics. 2 (1968),70. |
7. | | ipr-rat LD50:1200 mg/kg | | OYYAA2 Oyo Yakuri. Pharmacometrics. 2 (1968),70. |
8. | | ivn-rat LD50:300 mg/kg | | OYYAA2 Oyo Yakuri. Pharmacometrics. 2 (1968),70. |
9. | | orl-mus LD50:8900 mg/kg | | OYYAA2 Oyo Yakuri. Pharmacometrics. 2 (1968),70. |
10. | | scu-mus LD50:1800 mg/kg | | OYYAA2 Oyo Yakuri. Pharmacometrics. 2 (1968),70. |
11. | | <p class="cardite |
ETHAMBUTOL DIHYDROCHLORIDE Safety Profile
Poison by intravenous route. Moderately toxic by intraperitoneal and subcutaneous routes. Mildly toxic by ingestion. Human systemic effects: constriction of the pupil, visual field changes. Mutation data reported. When heated to decomposition it emits toxic fumes of NO
x and HCl. See also
AMINES.
Hazard Codes:
T: Toxic;
Risk Statements: R61: May cause harm to the unborn child
Safety Statements:
S53: Avoid exposure - obtain special instruction before use
S22: Do not breathe dust
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection
S45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)