Eltrombopag supplier | CasNO.496775-61-2

Name
Eltrombopag
EINECS 610-469-9
CAS No. 496775-61-2
Density 1.33 g/cm³
Solubility
Melting Point 242-244 °C
Formula C₂₅H₂₂N₄O₄
Boiling Point 656.8 °C at 760 mmHg
Molecular Weight 442.47
Flash Point 351 °C
Transport Information
Appearance Orange to red solid
Safety
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms Promacta;Revolade;3'-[2-[(2Z)-1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid;
PSA 114.59000
LogP 4.13840

Eltrombopag Specification

1. Introduction of Eltrombopag

Eltrombopag, with the systematic name of 3-[3-[(N'E)-N'-[1-(3,4-dimethylphenyl)-3-methyl-5-oxo-pyrazol-4-ylidene]hydrazino]-2-hydroxy-phenyl]benzoic acid, is one kind of white crystalline powder, odorless, little bitter taste. It should be stored in dry and cool environment.

2. Properties of Eltrombopag

The properties of the chemical are: (1)ACD/LogP: 4.06; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.59; (4)ACD/LogD (pH 7.4): 0.75; (5)#H bond acceptors: 8; (6)#H bond donors: 3; (7)#Freely Rotating Bonds: 6; (8)Polar Surface Area: 114.59 Å²; (9)Index of Refraction: 1.666; (10)Molar Refractivity: 123.53 cm³; (11)Molar Volume: 332 cm³; (12)Polarizability: 48.97×10^-24cm³; (13)Surface Tension: 52.5 dyne/cm; (14)Enthalpy of Vaporization: 101.61 kJ/mol; (15)Vapour Pressure: 3.79×10^-18 mmHg at 25°C._.

3. Structure Descriptors of Eltrombopag

You can still convert the following datas into molecular structure:
(1)SMILES: OC(=O)c1cccc(c1)c4cccc(N\N=C3C(\C)=N/N(c2ccc(C)c(C)c2)C3=O)c4O
(2)InChI: InChI=1/C25H22N4O4/c1-14-10-11-19(12-15(14)2)29-24(31)22(16(3)28-29)27-26-21-9-5-8-20(23(21)30)17-6-4-7-18(13-17)25(32)33/h4-13,26,30H,1-3H3,(H,32,33)/b27-22+
(3)InChIKey: XDXWLKQMMKQXPV-HPNDGRJYBX

Product Name

Eltrombopag

Eltrombopag Specification

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