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  • Name

    Ephedrine sulfate

  • EINECS 205-154-4
  • CAS No. 134-72-5
  • Density g/cm3
  • Solubility Freely soluble in water,sparingly soluble in alcohol.
  • Melting Point 248-250 ºC
  • Formula 2(C10H15NO).H2O4S
  • Boiling Point 255 °C at 760 mmHg
  • Molecular Weight 428.55
  • Flash Point 85.6 °C
  • Transport Information
  • Appearance white crystalline powder
  • Safety 22-25
  • Risk Codes R22   
  • Molecular Structure Molecular Structure of 134-72-5 (Ephedrine sulfate)
  • Hazard Symbols
  • Synonyms Bis[[R-(R*,S*)]-beta-hydroxy-alpha-methylphenethyl methylammonium] sulphate
  • PSA 147.50000
  • LogP 3.86560

Ephedrine sulfate Chemical Properties

Chemical Name: Ephedrine sulfate
CAS No.: 134-72-5
RTECS Class: Tumorigen; Drug; Mutagen; Human Data
Molecular Formula: C10H17NO5S
Molecular Weight: 263.31 g/mol
Melting Point: 248 °C
Following is the structure of Ephedrine sulfate (CAS No.134-72-5):


The chemical synonymous of Ephedrine sulfate (CAS No.134-72-5) are (-)-Ephedrinesulfate(2:1)(Salt ; 1-Alpha-(1-(Methylamino)Ethyl)Benzylalcoholsulfate ; 1-Phenyl-2-Methylamine-Propanol-1-Sulfate ; 2:1)(Salt) ; Alpha-[1-(Methylamino)Ethyl]-Benzenemethano[Theta-(Theta,S)]-Benzenemethanosulfate( ; Isofedrol ; L-Ephedrinesulfate ; Nci-C55652

Ephedrine sulfate Toxicity Data With Reference

1.    

ivn-hmn TDLo:1 mg/kg:CVS

     AEPPAE    Naunyn-Schmiedeberg’s Archiv fuer Experimentelle Pathologie und Pharmakologie. 120 (1927),189.
2.    

orl-rat LD50:404 mg/kg

     JPETAB    Journal of Pharmacology and Experimental Therapeutics. 94 (1948),150.
3.    

scu-rat LD50:318 mg/kg

     JPETAB    Journal of Pharmacology and Experimental Therapeutics. 94 (1948),150.
4.    

ivn-rat LD50:102 mg/kg

     JPETAB    Journal of Pharmacology and Experimental Therapeutics. 94 (1948),150.
5.    

orl-mus LD50:812 mg/kg

     NTPTR*    National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No. NTP-TR-307 ,1986.
6.    

ipr-mus LD50:400 mg/kg

     TXAPA9    Toxicology and Applied Pharmacology. 28 (1974),227.
7.    

orl-rbt LD50:825 mg/kg

     JPETAB    Journal of Pharmacology and Experimental Therapeutics. 94 (1948),150.
8.    

scu-rbt LD50:383 mg/kg

     JPETAB    Journal of Pharmacology and Experimental Therapeutics. 94 (1948),150.
9.    

ivn-rbt LD50:73 mg/kg

     JPETAB    Journal of Pharmacology and Experimental Therapeutics. 94 (1948),159.

Ephedrine sulfate Consensus Reports

NTP Carcinogenesis Studies (feed); No Evidence: mouse, rat NTPTR*    National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No. NTP-TR-307 ,1986. . Reported in EPA TSCA Inventory.

Ephedrine sulfate Safety Profile

Poison by intravenous, intraperitoneal, and subcutaneous routes. Moderately toxic by ingestion. Human systemic effects by intravenous route: increased pulse rate and blood pressure. When heated to decomposition it emits very toxic fumes of NOx and SOx. See also EPHEDRINE.
Hazard Codes: HarmfulXn
Risk Statements about Ephedrine sulfate (CAS No.134-72-5):
R22:Harmful if swallowed.
Safety Statements about Ephedrine sulfate (CAS No.134-72-5):
S22:Do not breathe dust. 
S25:Avoid contact with eyes.
Attention:
1. Storage: Keep containers tightly closed. Store protected from light. Store in a cool, dry area away from incompatible substances.
2. Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation. Store protected from light.

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