Product Name

  • Name

    Etazolate

  • EINECS
  • CAS No. 51022-77-6
  • Article Data2
  • CAS DataBase
  • Density 1.25 g/cm3
  • Solubility H2O: >20 mg/mL
  • Melting Point 193-194 ºC
  • Formula C14H19N5O2
  • Boiling Point 427.6 ºC at 760 mmHg
  • Molecular Weight 289.337
  • Flash Point 212.4 ºC
  • Transport Information
  • Appearance Off-White Solid
  • Safety 26-36
  • Risk Codes 36/37/38
  • Molecular Structure Molecular Structure of 51022-77-6 (Etazolate)
  • Hazard Symbols IrritantXi
  • Synonyms ETAZOLATE;ETAZOLATE HYDROCHLORIDE;1-ETHYL-4-[(1-METHYLETHYLIDENE)HYDRAZINO]-1H-PYRAZOLO-[3,4-B]-PYRIDINE-5-CARBOXYLIC ACID, ETHYL ESTER HYDROCHLORIDE;1-ETHYL-4-[(1-METHYLETHYLIDENE)HYDRAZINO]-1H-PYRAZOLO[3,4-B]PYRIDINE-5-CARBOXYLIC ACID ETHYL ESTER, HCL;SQ 20009;1-Ethyl-4-[2-(1-methylethylidene)hydrazinyl]-1H-pyrazolo[3,4-β]pyridine-5-carboxylic Acid Ethyl Ester;1-Ethyl-4-isopropylidenehydrazino- 1H-pyrazolo[3,4-β]-1-pyridine-5-carboxylic Acid Ethyl Ester;SQ 64442
  • PSA 81.40000
  • LogP 2.50860

Etazolate Specification

 Etazolate , with its cas register number 51022-77-6, its IUPAC Name is Ethyl 1-ethyl-4-(2-propan-2-ylidenehydrazinyl)pyrazolo[3,4-b]pyridine-5-carboxylate . It also can be called as Etazolato ; Etazolatum ; 1H-Pyrazolo(3,4-b)pyridine-5-carboxylic acid, 1-ethyl-4-((1-methylethylidene)hydrazino)-, ethyl ester ; Etazolate hydrochloride and so on. Etazolate acts as an anxiolytic, which is a pyrazolopyridine derivative drug. It is also acting as an adenosine antagonist, a subtype-selective GABAA receptor partial agonist, and a phosphodiesterase inhibitor selective for the PDE4 subtype. And Etazolate belongs to product categories such as All Inhibitors; Inhibitors; Intermediates & Fine Chemicals.

 Etazolate is a phosphodiesterase 4 (PDE4) inhibitor and GABAA receptor modulator that also stimulates alpha-secretase activity and neurotrophic soluble amyloid precursor protein (sAPPalpha) production, currently developed as a possible Alzheimer's disease therapeutic.  Besides, Etazolate is off-white solid and souble in water which solutions should be freshly prepared. Due to Etazolate is irritating to eyes, respiratory system and skin, we should wear suitable protective clothing in case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

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