Product Name

  • Name

    efloxate

  • EINECS
  • CAS No. 119-41-5
  • Article Data11
  • CAS DataBase
  • Density 1.265g/cm3
  • Solubility
  • Melting Point 123-124°
  • Formula C19H16 O5
  • Boiling Point 486.5°C at 760 mmHg
  • Molecular Weight 324.333
  • Flash Point 269.1°C
  • Transport Information
  • Appearance
  • Safety Moderately toxic by intraperitoneal route. When heated to decomposition it emits acrid smoke and irritating fumes.
  • Risk Codes
  • Molecular Structure Molecular Structure of 119-41-5 (efloxate)
  • Hazard Symbols
  • Synonyms Acetic acid,[(4-oxo-2-phenyl-4H-1-benzopyran-7-yl)oxy]-, ethyl ester (6CI,7CI,8CI,9CI); Angorlisin;Coril; Corosanin; Dilatan Kore; Domucor; Efloxate; Ethyl[(4-oxo-2-phenyl-4H-1-benzopyran-7-yl)oxy]acetate; Flacethyle; Oxiflavil;Oxyflavil; Re 1-0185; Recordil
  • PSA 65.74000
  • LogP 3.40190

Ethyl-7-hydroxyflavone Chemical Properties

IUPAC Name:  ethyl 2-(4-oxo-2-phenylchromen-7-yl)oxyacetate 
Synonyms of  Ethyl-7-hydroxyflavone (CAS NO.119-41-5): Efloxate ; Efloxate [INN:JAN] ; ((4-Oxo-2-phenyl-4H-1-benzopyran-7-yl)oxy)acetic acid ethyl ester ; 4-18-00-00695 (Beilstein Handbook Reference) ; 7-Flavone ethyl hydroxyacetate ; 7-Flavonoxyacetic acid ethyl ester ; 7-alpha-(Acetoxyethane)-oxyflavone ; Angorlisin ; BRN 0313027 ; CCRIS 5253 ; Coril ; Corosanin ; Dilatan kore ; Domucor ; EINECS 204-321-9 ; Eflossato ; Eflossato [DCIT] ; Efloxate ; Efloxato ; Efloxato [INN-Spanish] ; Efloxatum ; Ethyl 7-flavonoxyacetate ; Ethyl 7-hydroxyflavone ; Ethyl flavon-7-yloxyacetate ; Ethyl flavone-7-oxyacetate ; Ethyl-((4-oxo-2-phenyl-4H-1-benzopyran-7-yl)oxy) acetate ; Flacethyle ; Flavone-7-ethyl-oxyacetate ; Oxiflavil ; Oxyflavil ; RE 1-0185 ; REC 1-0185 ; Recordil ; UNII-CZU6V3902K ; ((4-Oxo-2-phenyl-4H-1-benzopyran-7-yl)oxy)acetic acid ethyl ester ; Acetic acid, ((4-oxo-2-phenyl-4H-1-benzopyran-7-yl)oxy)-, ethyl ester ; Efloxate ; Ethyl-((4-oxo-2-phenyl-4H-1-benzopyran-7-yl)oxy) acetate ;
Molecular Formula: C19H16O5            
Molecular Weight: 324.35 
Index of Refraction: 1.59
Surface Tension: 49.5 dyne/cm
Density: 1.265 g/cm3
Flash Point: 269.1 °C
Enthalpy of Vaporization: 75.23 kJ/mol
Boiling Point: 486.5 °C at 760 mmHg
Vapour Pressure: 1.28E-09 mmHg at 25°C
Properties: Crystals from 50% ethanol.
Molecular Structure:

Ethyl-7-hydroxyflavone Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 intraperitoneal 2gm/kg (2000mg/kg)   Drugs in Japan Vol. 6, Pg. 125, 1982.
mouse LD50 intraperitoneal 3200mg/kg (3200mg/kg)   Farmaco, Edizione Scientifica. Vol. 13, Pg. 561, 1958.
mouse LD50 oral > 5gm/kg (5000mg/kg)   Drugs in Japan Vol. 6, Pg. 125, 1982.
rat LD50 oral > 5gm/kg (5000mg/kg)   Drugs in Japan Vol. 6, Pg. 125, 1982.

Ethyl-7-hydroxyflavone Safety Profile

Moderately toxic by intraperitoneal route. When heated to decomposition it emits acrid smoke and irritating fumes.

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